Microbial Sciences PhD, MD, and MPhil Supervisors

Professor Peter Andrew

  • Molecular and cellular studies of host and bacterial responses in infection and disease and pathogen/environmental interactions especially involving Streptococcus pneumoniae and Listeria monocytogenes

Professor Mike Barer

  • Interface between bacterial physiology and human infections, principally those involving the gastrointestinal tract and tuberculosis

Professor Andrea Cooper

  • Definition of the factors impacting expression of immunity in the lung, particularly tuberculosis
  • The role of early innate events in driving coordinated immune responses
  • The role of cytokines and chemokines in initiation, expression and regulation of immunity
  • The role of lymphocyte priming, differentiation and migratory capacity in prolonged expression of immunity
  • The role of the inflamed environment in regulating the expression of immunity

Dr Primrose Freestone

  • Studies into microbial endocrinology
  • Relationship between stress and stress hormones and the progress of human and animal infection

Dr Natalie Garton - njg17@le.ac.uk

  • Lipid bodies of pathogenic bacteria, in particular Mycobacterium tuberculosis
  • Spectroscopic methods to monitor bacterial adaptation

Dr Galina Mukamolova

  • Molecular mechanisms of bacterial dormancy and resuscitation
  • Role of mycobacterial serine-threonine kinases in growth, cell wall remodelling and dormancy
  • Antimicrobial tolerance
  • Biomarkers of non-replicating persistence

Dr Helen O'Hare

  • Bacterial sensory perception and signal transduction
  • Regulation of bacterial metabolism (Mycobacterium tuberculosis)

Dr Cat Pashley - chp5@le.ac.uk

  • Understanding the role fungal allergy and/or colonisation plays in causing and exacerbating respiratory diseases such as asthma, COPD or cystic fibrosis
  • Investigating the interaction between the respiratory mycobiome and bacteriome
  • Understanding the effect antifungal or antibacterial drugs may have on the mycobiome and bacteriome
  • Developing approaches to identify and quantify fungal exposure in the environment
  • Understanding the relationship between fungal exposure and respiratory health
  • Investigating the role the environmental use of fungicides may have on the development of resistance to antifungal drugs used clinically

 

Professor Russell Wallis

  • Molecular changes that occur during initiation of the classical and lectin pathways of complement activation
  • Characterising the interactions between components that trigger complement activation

Dr Hasan Yesilkaya

  • Molecular analysis of bacterial virulence determinants of important human pathogens such as Klebsiella pneumoniae and Streptococcus pneumoniae.
  • Understanding in vivo survival mechanisms of microbes

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