All Microbial Sciences Resources

All resources for teaching microbial sciences in higher education

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Microbial genomes

Microbial Genomes - Lecture

A lecture written by Professor Julian Ketley highlighting key areas of bacterial genomics and the techniques used in this field.


Microbial Genomes
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Power Point presentation of lecture slides.
The lecture is aimed at second year undergraduate students. You can find information on this lecture, and also view it online here.

Open Helix Bioinformatics Tutorials

This site gives an introduction to genomics and bioinformatics with a wealth of resources for using programs to study genomics.


Resource: Open Helix
Approach: Interactive tutorials and webinars

Comparative Bacterial Genome Analysis using NGS

This review article is a beginners guide to using bacterial genome analysis and includes topics such as: assembly, ordering of contigs, annotation of genomes etc.


Resource: Edwards and Holt (2013)
Approach: Topic material

Comparison of Prokaryotic and Eukaryotic Genomes

This narrated video outlines the basic differences between prokaryotic/eukaryotic genes and genomes. This is a relatively basic analysis of genomics and would be best suited to first year undergraduates.


Resource: Genome comparison
Approach: Video

WGS in the Undergraduate Classroom

This paper outlines the use of a hands on sequencing project integrated into an undergraduate genomics module.


Resource: NCBI PMC
Approach: Lectures and practicals

An Introduction to Bioinformatics

This site contains tutorials for learning and teaching bioinformatics to beginners. Topics include an introduction to NCBI's BLAST program and linking genetic information to disease.


Resource: Bioinformatics in the classroom
Approach: Tutorials

Horizontal gene transfer

Bacterial Conjugation

This video demonstrates bacterial conjugation via a generic sex pilus in E. coli. This video highlights the molecular mechanisms and genetic elements involved in conjugal transfer and rolling circle replication.


Resource: Bacterial Conjugation
Approach: video

Rolling Circle Replication

This animation and accompanying quiz explains and reflects on rolling circle replication at the DNA level, as opposed to the mechanistic approach taken by the 'bacterial conjugation' resource above.


Resource: Rolling circle replication
Approach: animation and reflective quiz

Generalised Phage Transduction

This animation and accompanying quiz explains and reflects on the role phage transduction in horizontal DNA transfer.


Resource: phage transduction
Approach: animation and reflective quiz

Infection

Simulating Phase Variation in Campylobacter jejuni

This is an online tutorial visualising phase variation and expanding on concepts outlines in the phase variation part of the site. This tutorial should help students to understand the link between phase variation and disease in this pathogen. You can download the simulator, introductory sheet and answers below.


Simulating phase variationDownload 1Download 2
Introduction to phase variation PowerPoint
The simulator

Java applet

The introduction sheet

Word

pdf

The question sheet Word

pdf

The answer sheet Word

pdf

All Zip file
Resource: Simulating Phase variation
Approach: interactive simulation

Simulating Phase Variation in Neisseria meningitidis

This is an online tutorial visualising phase variation and expanding on concepts outlines in the phase variation part of the site. This tutorial should help students to understand the link between phase variation and disease in this pathogen. You can download the simulator, introductory sheet and answers below.


Simulating phase variationDownload 1Download 2
Introduction to phase variation

PowerPoint

The simulator

Java applet

The introduction sheet

Word

pdf
The question sheet

Word

pdf

The answer sheet

Word

pdf

All

Zip file

Resource: Simulating Phase variation
Approach: interactive simulation

Campylobacter Chemotaxis

This is an interactive PowerPoint containing videos outlining the molecular mechanisms underlying C.jejuni motility and chemotaxis. We recommend that you download the zip file below, as the videos embedded within the PowerPoint may not work unless they are grouped. Note: to access all files together you should use the GoogleDrive link. The PowerPoint link under download one does not have the videos (also downloadable below) embedded.


Understanding chemotaxisDownload 1Download 2
Content PowerPoint

PowerPoint

Chemotaxis in real time

MP4

Chemotactic signal transduction

MP4

Notes

Word

pdf

All GoogleDrive
Approach: Interactive ppt.

Virulence Factors of Bacterial Pathogens

A comprehensive overview of the virulence determinants of 30 common bacterial pathogens. Includes links to genome sequences, recent publications and overviews of all reported virulence determinants.


Resource: Virulence factors
Approach: Informative database

Immunity and vaccination

CDC- Vaccine preventable diseases

A database of vaccine preventable diseases and their details provided by the Centre for Disease Control and Prevention. Use of this resource with undergraduate fundamental biosciences students aims to encourage a multidisciplinary mind set to vaccination.


Resource: Centre for Disease Control and Prevention
Approach: Topic material

Overview of the immune system

This section of the Khan Academy website gives a comprehensive overview of the immune system to an undergraduate level through the use of narrated videos. Topics covered include: phagocytes, leukocyte function and antigen presentation.


Resources: Khan Academy
Approach: video

Bacteriophage

ViralZone - Bacteriophage

The ViralZone website is an accessible database of information about viruses at degree and postgraduate level. Within the site you can find pages on the life cycles and molecular biology of nearly all characterised bacteriophage.


Resource: ViralZone
Approach: content material

Killer Cure

This video produced by the Giorgi Eliava Institute of Bacteriophage, Microbiology and Virology highlights the use of phage therapy as a potential therapeutic option for the treatment of bacterial disease.


Resource: Killer cure
Approach: video

Bacteriophage Specificity

This laboratory based activity published by Allen, M and Gyure, R (2013) is intended for use with undergraduate microbiologists/virologists. The activity highlights the basic molecular biology of phage and phage specificity whilst also developing practical and critical thinking skills.


Resource: Allen, M and Gyure, R (2013)
Approach: lab activity
Citation: Allen, Mary E., and Ruth A. Gyure. "An Undergraduate Laboratory Activity Demonstrating Bacteriophage Specificity." Journal of Microbiology & Biology Education: JMBE 14.1 (2013): 84.

MicrobiologyBytes

MicrobiologyBytes is a blog featuring the latest microbiology news and research written by Dr Alan Cann of the University of Leicester. Dr Cann has a background in virological research and education. Whilst the subject matter of his blog is general microbiology, Dr Cann's background in virology make this an excellent resource for any under/postgraduate virologist.


Resource: MicrobiologyBytes
Approach: Subject material

Phage - an Undergraduate Overview

A collection of resources (including problem sets) outlining the molecular biology of phage and also their use in microbial biotechnology.


Resource: microbial genetics and phage
Approach: resource database

Antibiotic resistance

Antibiotic Action (AA) Resources

Antibiotic Action are a global initiative aimed at education around antibiotic resistance. Their site is regularly updated to include the latest advancements in antibiotic resistance research.


Resources: AA
Approach: topic material

Antibiotic Resistance in Veterinary Medicine

An online pool of teaching modules regarding antimicrobial resistance in veterinary medicine.


Resource: AMR for vets
Approach: topic material

AMR Infographics

A series of inforgraphics highlighting the effect of antimicrobial resistance on human health and the economy.


Resource: review on antimicrobial resistance
Approach: visual aids

Resistance Map

An interactive tool visualising the change in antibiotic resistance observed in clinical isolates in countries of the world compared to their use.


Resource: resistance map
Approach: visual aids

Antibiotic Resistance Database

This online tutorial allows users to learn the basics of antibiotic resistance gene annotation, and how to derive AMR relevant information from genome sequences.


Resource: ARDB tutorial
Approach: online tutorial

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