LCBRU News, Media and Events

Leicester daredevil to set pulse racing in charitable sky dive

Posted by kg198 at Feb 23, 2017 02:00 PM |

A Leicester daredevil is set to make her pulse race by jumping out of a plane to raise money for the British Heart Foundation (BHF).

Kel GreenKelley Green, who is a senior administrator from the NIHR Leicester Cardiovascular Biomedical Research Unit (BRU) at Glenfield Hospital, will embark upon her “heart-stopping challenge” in March.

The 37-year-old thrill seeker said: “My sky dive will raise money for the British Heart Foundation, which fund many of the research studies within the unit.

“It’s a hugely important charity because it’s helped halve the number of people dying from heart and circulatory disease in the UK.”

Kelley’s own family have been affected by heart problems with her father receiving stent treatment and her father-in-law having passed from a condition involving blocked arteries.

She added: “He passed away years ago, which was very sad. However, he would probably have survived the condition had he become ill now, because treatment has moved on so much.

“Sadly every day hundreds of people are still losing their lives. BHF research can help create new treatments and discover new cures.”

The NIHR Leicester Cardiovascular Biomedical Research Unit at Glenfield Hospital is a partnership between the University of Leicester and University Hospitals of Leicester NHS Trust.

Unit Manager Dr Martin Batty said: “We are hugely proud of Kelley and we’re all getting behind her. We felt it was rather fitting that someone who works for a heart research centre has chosen to be part of such a heart-stopping challenge.

“We wish her lots of luck and hope she manages to raise lots of money for the British Heart Foundation.

The NIHR BRUs are focused on translational clinical research, taking new ideas from the laboratory bench to the patient’s bedside to improve health.

The NIHR Leicester Cardiovascular BRU at Glenfield Hospital harnesses the power of experimental science to explore and develop ways to help prevent and treat cardiovascular conditions.

The BRU is one of 20 units around England funded by the NIHR, the research arm of the NHS.

The BHF was founded in 1961 with the aim to fund pioneering research that paved
the way for life-saving treatments.

Kelley will complete her sky dive on Saturday, 25 March in Nottingham. She can be sponsored here:

Controversial test could be leading to unnecessary open heart operations

Posted by mb543 at Feb 15, 2017 02:30 PM |

An approved international test to check whether people need open heart surgery could be sending twice as many people under the knife unnecessarily, according to new research.

It is thought the unnecessary operations could be costing as much as £75 million.

The study was carried out as part of a NIHR Fellowship for Professor Gerry McCann, who is NIHR Fellowship, who is a cardiologist from the NIHR Leicester Cardiovascular Biomedical Research Unit (BRU).

Since 2012 doctors have been using exercise testing on people with a condition called aortic stenosis (AS) to determine whether they need an operation to save their life.

Professor McCann

Professor McCann, who is also Professor of Cardiac Imaging and Honorary Consultant Cardiologist from the University of Leicester Department of Cardiovascular Sciences, has shown the current approach is “hugely inaccurate” and if followed may send thousands of patients to surgery before it is needed.

The exercise test, which involves cycling on a stationary bike, is used to determine whether surgery is needed for people with the condition – but it only has a 60 per cent accuracy rate, the study found.

AS, which is the narrowing of the aortic heart valve, affects predominantly older people and affects up to three per cent of people over 75 years of age. Symptoms, such as chest pain, breathlessness and feeling faint, can take years to develop. However, when they do it means the person is seriously ill and could die from heart failure or sudden death.

If exercise test participants become breathless, they are recommended to have valve replacement therapy. About 10,000 aortic valve replacements are performed every year at a cost of up to £15,000. Hospital recuperation then takes between seven and 10 days.

Professor McCann said: “There is no doubt that valve replacement therapy is highly effective for patients with symptoms, however there are risks involved. It’s a major operation and there’s a one per cent chance of people dying or having a stroke during or after. There’s also the chance they could develop an infection.

“It can often take six months to recover, but if they survive they tend to do very well afterwards. However, if we know a patient has AS and no symptoms and we do nothing there’s also a one per cent chance they will die so there’s a fine line between whether we should intervene or not.

“Our findings showed that this exercise test, which has been approved by the American Heart Association/American College of Cardiology and the European Society of Cardiology, was highly inaccurate as almost twice the number of people who became breathless during the test did not develop symptoms within a year.”

The findings have been published in the world-leading European Heart Journal, which showcases work often considered in future guidelines.

Professor McCann now wants to conduct further research to find a more accurate way to determine whether doctors should wait for symptoms to develop or to intervene beforehand. Ultimately a clinical study comparing early surgery versus waiting for symptoms to develop is needed.

The study was funded by the NIHR and most of the research was carried out at the NIHR Leicester Cardiovascular BRU.

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NIHR Leicester Cardiovascular Biomedical Research Unit
BHF Cardiovascular Research Centre
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