Study highlights need for better treatment of heart failure patients

Posted by ap507 at Mar 28, 2018 09:12 AM |
Research highlights most predominant symptoms of cardiovascular morbidities

Issued by the University of Leicester on 26 March

A new study by researchers from the Universities of Leicester and Keele, has highlighted the need for better treatment of heart disease patients suffering from additional chronic conditions.

Guidelines currently advise clinicians to focus on the patient's cardiovascular status, ignoring their non-cardiovascular disorders and symptoms, despite these often having a bigger burden on their quality of life.

Heart failure is a common chronic and progressive condition, where the heart muscle is unable to pump enough blood through the body to meet the body’s needs. These patients often suffer with one or more additional chronic conditions, otherwise known as comorbidities.

Researchers at the University of Leicester and Keele University worked with Linkoping University and the Australian Catholic University, to develop a new healthcare model which considers both the patient's cardiovascular and non-cardiovascular comorbidities, using data from 10,575 heart failure patients in the Swedish Heart Failure Register. The study findings were published today in PLOS Medicine.

The study showed that the most predominant symptoms of cardiovascular comorbidities were pain and anxiety, whereas shortness of breath, leg swelling, and fatigue were common symptoms of non-cardiovascular comorbidities.

These non-cardiovascular conditions were found to have a much higher burden on the patients’ quality of life and more severe symptoms than the cardiovascular conditions.

Dr Claire Lawson, a Lecturer at the University of Leicester who carried out the research as a Lecturer at Keele University, commented: “This study highlights the lack of understanding about the relationship among different comorbidities, and the quality of life for patients with heart failure. It demonstrates the importance to develop guidance for the use of an individualised treatment approach for these patients.” 

Keele University Senior Lecturer, Dr Ivonne Solis-Trapala, added: “Although these findings are limited because of the cross-sectional nature of the study, they provide considerable evidence that targeting specific comorbidities and their associated symptoms could be an effective approach in treating patients with heart failure.

The paper will be available here after the embargo lifts: 


Notes to editors:

For enquiries, please contact Dr Claire Lawson on

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