Deprivation responsible for 450 breast cancer deaths each year

Posted by er134 at Nov 02, 2013 10:35 AM |
Researchers from Universities of Leicester and Cambridge present findings

Issued by University of Leicester Press Office on 2 November 2013

Deprivation could be responsible for around 450 deaths from breast cancer every year in England as women in lower income groups are likely to be diagnosed when the disease is more advanced, and treatment is less effective.

Research presented today at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool, and funded by Cancer Research UK, examined the effect deprivation has on the stage at which women are diagnosed with breast cancer, and how many lives are lost as a result.

The researchers, based at the Universities of Leicester and Cambridge, looked at the stage of breast cancer in over 20,000 women diagnosed between 2006-2010 using data from the National Cancer Registration Service (Public Health England). They then calculated the number of lives that would be saved within 5 years of diagnosis if the stage at diagnosis for all deprivation groups matched those of the most affluent women.

The study estimates that 40 lives would be saved every year in Eastern England if these socioeconomic differences were removed, equivalent to around 450 lives saved in the whole of England every year.

Dr Mark Rutherford, of the University of Leicester Department of Health Sciences, said: "Research has shown that diagnosing breast cancer at an earlier stage has a significant impact on the chances of survival. Our study highlights that we could make major improvements in terms of the number of early deaths that are seen for women living in more deprived areas by ensuring that these women are diagnosed earlier."

Dr Gary Abel, statistician at the University of Cambridge and study author, said: “These avoidable deaths are not due to differences in the response to treatment, or the type of breast cancer. Rather these are deaths that might be avoided if cancer was caught as early in women from deprived backgrounds as those from more affluent backgrounds.

“The reason for this inequality may be a combination of these women being less aware of breast cancer symptoms and a greater reluctance to see their GP.”

Dr Julie Sharp, head of health information at Cancer Research UK, said: “Other research shows that women from deprived backgrounds are more likely to feel embarrassed or worried about going to their GP – but it’s important for women to take that step as going to the GP promptly could make all the difference.

“All women should be aware of how their breasts normally look and feel because we know that early diagnosis is one of the most important factors in whether breast cancer treatment is effective.”

The researchers from the University of Leicester Department of Health Science are Dr Mark Rutherford, Dr Sally Hinchliffe, and Professor Paul Lambert.


Notes to Editors:

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View Conference abstract here -

To access the scientific paper related to this collaboration see:

Rutherford MJ, Hinchliffe SR, Abel GA, Lyratzopoulos G, Lambert PC, Greenberg DC. How much of the deprivation gap in cancer survival can be explained by variation in stage at diagnosis: an example from breast cancer in the East of England. Int J Cancer. 2013;133(9):2192-200.

About the NCRI Cancer Conference

The National Cancer Research Institute (NCRI) Cancer Conference is the UK’s major forum for showcasing the best British and international cancer research. The Conference offers unique opportunities for networking and sharing knowledge by bringing together world-leading experts from all cancer research disciplines. The ninth annual NCRI Cancer Conference is taking place from 3–6 November 2013 at the BT Convention Centre in Liverpool. Roche is the principal sponsor of the 2013 NCRI Cancer Conference.

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About the NCRI

The National Cancer Research Institute (NCRI) was established in 2001. It is a UK-wide partnership between the government, charity and industry which promotes cooperation in cancer research.
NCRI members are: the Association of the British Pharmaceutical Industry (ABPI); Association for International Cancer Research; Biotechnology and Biological Sciences Research Council; Breakthrough Breast Cancer; Breast Cancer Campaign; Cancer Research UK; Children with Cancer UK; Department of Health; Economic and Social Research Council; Leukaemia & Lymphoma Research; Ludwig Institute for Cancer Research; Macmillan Cancer Support; Marie Curie Cancer Care; Medical Research Council; Northern Ireland Health and Social Care (Research & Development Office); Prostate Cancer UK; Roy Castle Lung Cancer Foundation; Scottish Government Health Directorates (Chief Scientist Office); Tenovus; Welsh Government (National Institute for Social Care and Health Research); The Wellcome Trust; and Yorkshire Cancer Research.

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