'Mesolimbic Dopamine: Reward Prediction in Action?'

Series Name Department of Neuroscience, Psychology & Behaviour
Speaker Mark Walton, University of Oxford
Type Lectures & Talks
When 05 Nov 2015, 03:00PM - 04:00PM
Venue Frank & Katherine May Lecture Theatre, Henry Wellcome
Open To University staff and students
For Bookings Contact Emma Gisborn egg3@le.ac.uk

Speaker: Mark Walton, University of Oxford

When: 3pm on Thursday 5th November 2015

Where: Frank & Katherine May Lecture Theatre, Henry Wellcome

Mesolimbic Dopamine: Reward Prediction in Action?

It is widely held that the activity of many dopamine neurons encodes a quantitative reward prediction error, which can act as a teaching signal to represent and update predictions of future rewards. A largely separate literature has also implicated striatal dopamine transmission as critical for driving behavioural responses and action initiation. However, to date, the precise relationship between dopamine release, reward prediction, movement and economic choice remains ambiguous. I will discuss a series of ongoing electrochemistry studies in rats where we monitor sub-second dopamine release dynamics directly in the striatum as they make or withhold responses to attempt to understand the relationship between rapid changes in dopamine, net value and movement.

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