Connection between low blood glucose and cardiovascular events revealed

Posted by ap507 at Dec 12, 2014 02:42 PM |
International team led by University of Leicester publish new findings

A study involving scientists Professors Kamlesh Khunti (pictured) and Melanie Davies from the Diabetes Research Centre has established a link between hypoglycaemia and increased risk of cardiovascular events and mortality in patients with diabetes, which could lead to changes in the way some patients’ treatment is managed.

The study, which has been published in the academic journal Diabetes Care, demonstrated that, following hypoglycaemia, insulin-treated patients with diabetes had an ~60% higher risk of cardiovascular events, and were between 2–2.5 times more likely to die over the same period as patients who did not experience hypoglycaemia.

The research was supported by the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care East Midlands (NIHR CLAHRC EM), and the NIHR Leicester–Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit.

Patients with diabetes are at higher risk of cardiovascular disease due to the formation of atherosclerotic plaques in blood vessels; this is a major cause of early death in these patients. The results of the study show that hypoglycaemia, which occurs when a patient’s blood glucose becomes dangerously low, can trigger potentially fatal cardiovascular events.

The findings of this investigation are a stark reminder of the challenges facing patients with diabetes and could lead to changes in the management of insulin-treated patients, particularly those at high risk of cardiovascular events.

Share this page: