Festival of Postgraduate Research - Preview no.6

Posted by mjs76 at Jun 15, 2011 10:00 AM |
Postgraduate posters from the Department of Cardiovascular Sciences.

Tomorrow is our annual Festival of Postgraduate Research. A chance for some of our best postgrads to present posters of their work. In the run-up to the Festival, we’re summarising the presentations on Newsblog, grouped into slightly arbitrary bundles. Today we’re taking a look at research in the Department of Cardiovascular Sciences.

Dissecting Mechanisms of Information Transfer within a Cardiac Potassium Channel

Hussein N Rubaiy (Department of Cardiovascular Sciences)

Hussein’s research examines ion channels, proteins which allow transfer of materials across cell membranes. In particular, Hussein is studying ‘KATP channels’ which have important functions in tissue protection and are a major drug target for Type 2 diabetes. A greater understanding of precisely how these channels interact with other proteins could lead to better targeted drugs for diabetes and other cardiovascular conditions. Earlier this year Hussein presented a paper at the Annual Symposium on Recent Advances in Membrane Biochemistry and was lead author on a paper about this topic published in the Biophysical Journal.

Quest for new therapeutic targets in the treatment of Coronary Heart Disease - Scanning the Human Genome for novel genetic markers

Peter Braund (Department of Cardiovascular Sciences)

Peter is researching ‘snips’, properly known as SNPs or single nucleotide polymorphisms. These are DNA sequences which can be useful genetic markers for common diseases. His particular interest in is Coronary Artery Disease (CAD), the leading single cause of death in the UK. Although some CAD risk factors are lifestyle-related, there is also a genetic element. Identifying SNPs in patients with and without Coronary Artery Disease can provide new ideas for drugs and other treatments.

Squeeze an Arm, Protect the Heart - Improving Outcomes After Heart Attack

Sadat Ali Edroos (Department of Cardiovascular Sciences)

Sadat’s research sounds deceptively simple. Temporarily stopping the blood supply to a muscle can makes it resistant to further damage – and this protection can be transferred from one muscle to another. Sadat is examining how this process, called ‘conditioning’, could be applied to a practical system where protection can be transferred from accessible muscles, such as those in the arm, to the body’s most important muscle, the heart.

The 'lego-isation' of biology using systems and synthetic biology

alawo.jpg
Deborah Alawo

Deborah Alawo (Department of Cardiovascular Sciences)

Deborah is using ‘systems biology’ techniques to develop a computer model of a chemical pathway involved in the growth of blood vessels. This model can then be used to create a ‘Biobrick’ of DNA which can be combined with other Biobricks in a process called ‘synthetic biology’. Ultimately this has potential for new understanding of, and treatment for, serious conditions such as stroke and cancer.

Chemical Safety: Getting to the Heart of the Problem

William Dott (Department of Cardiovascular Sciences)

Heart disease is the most common cause of death in Western culture and there are many possible contributing factors including chemicals such as pharmaceutical drugs or environmental agents. Identifying the effect of these chemicals on the heart is a challenging process and currently involves, among other tests, animal experimentation. William’s research examines the possibility of developing a surrogate cell model which could replace these experiments.

Visit the Festival of Postgraduate Research

The Festival of Postgraduate Research 2011 will be held in the Belvoir Suite on the Second Floor of the Charles Wilson Building between 11.00am and 1.00pm on Thursday 16 June. Entry is free so come along, browse the posters and talk with some of Britain’s brightest young postgrads.

See also:

  • Preview no.1: Physics and Astronomy, Engineering, Mathematics and Computer Science
  • Preview no.2: English, Archaeology and Ancient History, Education, Economics and Sociology
  • Preview no.3: Psychology, Medical and Social Care Education, Cancer Studies and Molecular Medicine and Health Sciences
  • Preview no.4: Geography, Geology and Chemistry
  • Preview no.5: Cell Physiology and Pharmacology, Infection Immunity and Inflammation, Biology and Biochemistry