Dr Sherif Gonem

E-mail: sg330@le.ac.ukSherif Gonem.jpg
Tel. 0116 2583486

Research interests:

- Effects of the environment on asthma

- Home monitoring and self-management of asthma using mobile technology

- Risk prediction algorithms for asthma

- Use of biomarkers to titrate asthma therapy



Original research articles

 Gonem S*, Berair R*, Singapuri A, Hartley R, Laurencin MF, Bacher G, Holzhauer B, Bourne M, Mistry V, Pavord ID, Mansur AH, Wardlaw AJ, Siddiqui SH, Kay RA, Brightling CE. Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial. Lancet Respir Med. 2016; 4(9): 699-707. *Joint first authors.

 Nanda CR, Singapuri A, Soares M, Monteiro W, Siddiqui S*, Gonem S*. Domiciliary exhaled nitric oxide and eosinophilic airway inflammation in adults with asthma. Eur Respir J. 2016; 48(1): 242-4. *Joint senior authors.

 Gonem S, Hardy S, Buhl N, Hartley R, Soares M, Kay R, Costanza R, Gustafsson P, Brightling CE, Owers-Bradley J, Siddiqui S. Characterization of acinar airspace involvement in asthmatic patients by using inert gas washout and hyperpolarized 3helium magnetic resonance. J Allergy Clin Immunol. 2016; 137(2): 417-25.

 Gonem S, Scadding S, Soares M, Singapuri A, Gustafsson P, Ohri C, Range S, Brightling CE, Pavord I, Horsley A, Siddiqui S. Lung clearance index in adults with non-cystic fibrosis bronchiectasis. Respir Res. 2014 May 18; 15:55.

 Gonem S, Corkill S, Singapuri A, Gustafsson P, Costanza R, Brightling CE, Siddiqui S. Between-visit variability of small airway obstruction markers in patients with asthma. Eur Respir J. 2014; 44(1): 242-4.

 Gonem S, Singer F, Corkill S, Singapuri A, Siddiqui S, Gustafsson P. Validation of a photoacoustic gas analyser for the measurement of functional residual capacity using multiple breath inert gas washout. Respiration. 2014; 87(6): 462-8.

 Gonem S, Natarajan S, Desai D, Corkill S, Singapuri A, Bradding P, Gustafsson P, Costanza R, Kajekar R, Parmar H, Brightling CE, Siddiqui S. Clinical significance of small airway obstruction markers in patients with asthma. Clin Exp Allergy. 2014; 44(4): 499-507.

 Gonem S*, Umar I*, Burke D, Desai D, Corkill S, Owers-Bradley J, Brightling CE, Siddiqui S. Airway impedance entropy and exacerbations in severe asthma. Eur Respir J. 2012; 40(5): 1156-63. *Joint first authors.

 Review articles

 Gonem S, Raj V, Wardlaw AJ, Pavord ID, Green R, Siddiqui S. Phenotyping airways disease: An A to E approach. Clin Exp Allergy. 2012; 42(12): 1664-83.

 Siddiqui S, Gonem S, Wardlaw AJ. Advances in the management of severe asthma. Semin Respir Crit Care Med. 2012; 33(6): 666-84.

 Brightling CE, Gupta S, Gonem S, Siddiqui S. Lung damage and airway remodelling in severe asthma. Clin Exp Allergy. 2012; 42(5): 638-49.

 Gonem S, Desai D, Siddiqui S, Brightling CE. Evidence for phenotype-driven treatment in asthmatic patients. Curr Opin Allergy Clin Immunol. 2011; 11(4): 381-5.


 Gonem S. Diagnosis in Acute Medicine. Oxford: Radcliffe Publishing; 2010.



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Institute of Lung Health

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Postal Address

Department of Infection, Immunity and Inflammation

Institute for Lung Health

Department of Respiratory Medicine
Glenfield Hospital

Groby Road


+44 (0)116 250 2787