Institute for Lung Health

The work of the Leicester Institute for Lung Health

Investigating Lung Cells

The Leicester Institute for Lung Health (ILH) was established by the Senate of the University of Leicester in 2000 to act as an umbrella for all those engaged in respiratory research and clinical development in Leicester.

Its members are senior academics, clinicians and para-clinical staff involved in respiratory medicine in Leicester. It encompasses research done within the University's Respiratory Science Dept and the NIHR Leicester Respiratory Biomedical Research Centre (BRC). Most of its members are within the university Department of Infection Immunity and Inflammation and the University Hospitals of Leicester NHS Trust.

It includes research done within the adult respiratory medicine group based at Glenfield Hospital, paediatric researchers based at the Leicester Royal Infirmary site and respiratory infections scientists based on the main university campus. Research undertaken under the auspices of the ILH ranges from health services research involving changes in NHS practice to clinical trials of new therapeutic entities, experimental medicine, genetics of lung function, microbial pathogenesis and animal models of lung infections.

A key role for the ILH has been to foster a seamless interaction between researchers employed by the University and the NHS the success of which was a major factor in the award of the respiratory BRC to Leicester in 2011.

Members of the ILH have attracted over £60 million in research funding since 2006 and have published over 200 papers affiliated to the ILH including six papers in the New England Journal of Medicine since 2002:

And two of the ten most highly cited original papers in asthma over the last decade; Green et al Lancet 2002 Nov 30;360(9347):1715-21 and Brightling et al, NEJM 2002 May 30;346(22):1699-705.

A key focus of the ILH is its annual research day.

 

Success at inaugral Research Impact Awards

The team with their award

Congratulations to our Respiratory colleagues who were successful at the inaugural Research Impact awards ceremony held at Stanford Court on 27 June 2017. The award was Best Societal Impact (achieved) and was awarded to Professor Andy Wardlaw and colleagues (pictured).

A close, collaborative relationship with GlaxoSmithKline led to the study of new drug mepolizumab in severe, exacerbation prone, eosinophilic asthma. This study was successful in demonstrating about a 50% reduction in severe exacerbations, eventually leading GSK to obtain a global licence for mepolizumab (as NucalaTM), in late 2015. In December 2016, NICE approved the treatment for severe eosinophilic asthma.

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Institute of Lung Health

Contact Us

Postal Address

Department of Infection, Immunity and Inflammation

Institute for Lung Health

Department of Respiratory Medicine
Glenfield Hospital

Groby Road
Leicester
LE3 9QP
UK

Fax

+44 (0)116 250 2787

Email

ilh@le.ac.uk