Breakthrough in search for neurodegenerative disease treatments

Posted by egg3 at Apr 26, 2013 10:46 AM |
University of Leicester geneticist among team investigating promising compound

A significant breakthrough has been made by scientists at the University of Leicester and the University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington’s, Alzheimer’s and Parkinson’s.

Researchers at the Manchester Institute of Biotechnology have detailed how an enzyme in the brain interacts with a drug-like lead compound for Huntington’s disease to inhibit its activity.

Dr Flaviano Giorgini (pictured) from the world-renowned Department of Genetics at the University of Leicester initiated the study and spearheaded the project along with Professor Scrutton, from the University of Manchester.

Their findings demonstrate that it can be developed as a potential treatment for neurodegenerative diseases. The research is published in the journal Nature.

Dr Giorgini's research is also featured in a video which forms part of a collection of resources on the use of model organisms in medical research. Watch Dr Giorgini's contribution below from 1:55.

Press release

 

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