Publications List

Moiseeva EP, Straatman KR, Leyland ML, Bradding P (2014) CADM1 Controls Actin Cytoskeleton Assembly and Regulates Extracellular Matrix Adhesion in Human Mast Cells. PLoS ONE 9(1): e85980.doi:10.1371/journal.pone.0085980.

Moiseeva, E. P., Roach, K. M., Leyland, M. L., & Bradding, P. (2013). CADM1 is a key receptor mediating human mast cell adhesion to human lung fibroblasts and airway smooth muscle cells.. PLoS One, 8(4), e61579. doi:10.1371/journal.pone.0061579

Moiseeva, E. P., Leyland, M. L., & Bradding, P. (2013, April). CADM1 is expressed as multiple alternatively spliced functional and dysfunctional isoforms in human mast cells.. Mol Immunol, 53(4), 345-354. doi:10.1016/j.molimm.2012.08.024

Ashmole, I., Duffy, S. M., Leyland, M. L., Morrison, V. S., Begg, M., & Bradding, P. (2012, June). CRACM/Orai ion channel expression and function in human lung mast cells.. J Allergy Clin Immunol, 129(6), 1628-35.e2. doi:10.1016/j.jaci.2012.01.070

Moiseeva, E. P., Leyland, M. L., & Bradding, P. (2012). CADM1 isoforms differentially regulate human mast cell survival and homotypic adhesion. Cellular and Molecular Life Sciences, 69, 2751-2764. doi:10.1007/s00018-012-0948-y

Tully, M. D., Grossmann, J. G., Phelan, M., Pandelaneni, S., Leyland, M. & Lian, L. -Y. (2012, January 31). Conformational characterization of synapse-associated protein 97 by nuclear magnetic resonance and small-angle X-ray scattering shows compact and elongated forms. Biochemistry, 51(4), 899-908. doi:10.1021/bi201178v

Ashmole, I., Duffy, S. M., Bradding, P., Leyland, M. L., Morrison, V. S., & Begg, M. (2012, June). CRACM/Orai ion channel expression and function in human lung mast cells. Journal of Allergy and Clinical Immunology, 129(6), 1628-1635. doi:10.1016/j.jaci.2012.01.070

Fomina, S, Howard, T. D., Sleator, O. K., Golovanova, M., O'Ryan, L., Leyland, M. L., Grossmann, J. C., Collins, R. F. & Prince, S. M. (2011, October). Self-directed assembly and clustering of the cytoplasmic domains of inwardly rectifying Kir2.1 potassium channels on association with PSD-95. Biochimica et Biophysica Acta - Biomembranes, 1808(10), 2374-2389. doi:10.1016/j.bbamem.2011.06.021

Cruse, G., Kaur, D., Leyland, M., & Bradding, P. (2010, October 10). A novel Fc RI -chain truncation regulates human mast cell proliferation and survival.. FASEB Journal, 24(10), 4047-4057. doi:10.1096/fj.10-158378

Cruse, G., Yang, W., Duffy, S. M., Chachi, L., Leyland, M., Amrani, Y. & Bradding, P. (2010, January 1). Counterregulation of beta2-adrenoceptor function in human mast cells by stem cell factor. Journal of Allergy and Clinical Immunology, 125(1), 257-263. doi:10.1016/j.jaci.2009.08.020

Lee, Y. M., Thompson, G. A., Ashmole, I., Leyland, M., So, I., & Stanfield, P. R. (2009, February 2). Multiple residues in the P-region and M2 of murine Kir 2.1 regulate blockage by external Ba2+. Korean Journal of Physiology and Pharmacology, 13(1), 61-70. doi:10.4196/kjpp.2009.13.1.61

Goult, B. T., Rapley, J. D., Dart, C., Kitmitto, A., Grossmann, J. G., Leyland, M. L., .& Lian, L. Y. (2007). Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1.. Biochemistry, 46, 14117-14128.

Cao, J., Viholainen, J. I., Dart, C., Warwick, H. K., Leyland, M. L., & Courtney, M. J. (2005, January 1). The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 strss-activated protein kinase activation and cell death.. Journal of Cell Biology, 168, 117-126. doi:10.1083/jcb.200407024

Leyland, M. L., & Dart, C. (2004, August 8). An alternatively spliced isoform of PSD-93/Chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1. Journal of Biological Chemistry, 279, 43427-43436. doi:10.1074/jbc.M407575200

Sampson, L. J., Leyland, M. L., & Dart, C. (2003, October 10). Direct interaction between the actin-binding Protein filamin-A and the inwardly rectifying potassium channel, Kir2.1. Journal of Biological Chemistry, 278, 41988-41997. doi:10.1074/jbc.M307479200

So, I., Ashmole, I., Soh, H., Spencer, P. J., Leyland, M. L., & Stanfield, P. R. (2003). Intrinsic gating in inward rectifier potassium channels (Kir2.1) with low polyamine affinity generated by site-directed mutagenesis.. Korean Journal of Physiology and Pharmacology, (7), 131-142.

Duffy, S. M., Leyland, M. L., Conley, E. C., & Bradding, P. (2001, April 4). Voltage-dependent and calcium-activated ion channels in the human mast cell line HMC-1. Journal of Leukocyte Biology, 70, 233-240.

Dart, C., & Leyland, M. L. (2001). Targeting of an A Kinase-anchoring protein, AKAP-79, to an inwardly rectifying potassium channel, Kir2.1. Journal of Biological Chemistry, (276), 20499-20505. doi:10.1074/jbc.M101425200

Thompson, G. A., Leyland, M. L., Ashmole, I., Sutcliffe, M. J., & Stanfield, P. R. (2000, July 7). Residues beyond the selectivity filter of the K+ channel Kir2.1 regulate permeation and block by external Rb+ and Cs+. Journal of Physiology, 15(526 Pt 2), 231-240.

Thompson, G. A., Leyland, M. L., Ashmole, I., Stanfield, P. R., & Sutcliffe, M. J. (2000, July 15). Residues beyond the selectivity filter of the K channel Kir2.1 regulate permeation and block by external Rb and Cs. Journal of Physiology, 526(2), 231-240.

Leyland, M. L., Spencer, P. J., Sutcliffe, M. J., Dart, C., & Stanfield, P. R. (1999). The possible role of a disulphide bond in forming functional Kir2.1 potassium channels. Pflugers Archiv European Journal of Physiology, 438(6), 778-781. doi:10.1007/s004240051106

Dart, C., Leyland, M. L., Stanfield, P. R., Spencer, P. J., & Sutcliffe, M. J. (1999). Topology of the pore region of an inward rectifier K channel, Kir2.1. Annals of the New York Academy of Sciences, 868, 414-417. doi:10.1111/j.1749-6632.1999.tb11303.x

Dart, C., Leyland, M. L., Barrett-Jolley, R., Shelton, P. A., Stanfield, P. R., Spencer, P. J., . & Sutcliffe, M. J. (1998, August 15). The dependence of Ag block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter. Journal of Physiology, 511(1), 15-24. doi:10.1111/j.1469-7793.1998.015bi.x

Dart, C., Leyland, M. L., Stanfield, P. R., Spencer, P. J., & Sutcliffe, M. J. (1998, August 15). The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis. Journal of Physiology, 511(1), 25-32. doi:10.1111/j.1469-7793.1998.025bi.x

Chan, W. C., Leyland, M., Clark, J., Dodd, H. M., Lian, L. Y., Gasson, M. J. & Roberts, G. C. (1996, July 22). Structure-activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin.. FEBS Lett, 390(2), 129-132.

Hingamp, P. M., Leyland,  M. L., Webb, J., Twigger, S., Mayer, R. J. and Dixon, L. K. (1995) Characterisation of a ubiquitinated protein which is externally located in African swine fever virions. Journal of Virology 69, 1785-1793.

Chan, W. C., Bycroft, B. W., Leyland, M. L., Lian L.-Y., and Roberts, G. C. K. (1993) A novel post-translational modification of the peptide antibiotic subtilin: isolation and characterisation of a natural variant from Bacillus subtilis A.T.C.C. 6633. Biochemical Journal 291, 23-27.

Chan, W. C., Bycroft, B. W., Leyland, M. L., Lian L.-Y., Yang, J. C. and Roberts, G. C. K. (1992) Sequence specific resonance assignment and conformational analysis of subtilin by 2D NMR. FEBS Letters 300, 56-62.

Leyland, M. L. and  Kelly, D. J. (1991) Purification and characterisation of a monomeric isocitrate dehydrogenase with dual coenzyme specificity from the photosynthetic bacterium Rhodomicrobium vannielii. European Journal of Biochemistry 202, 85-93.

Leyland, M. L.,  Hamblin M. J.  and Kelly, D. J. (1989) Eubacterial isocitrate dehydrogenase with dual specificity for NAD and NADP from Rhodomicrobium vannielii. FEMS Microbiology Letters 58, 165-170.

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