Biomolecular Kinetics

Biomolecuar Kinetics: a step-by-step guide ISBN 9781498727235 CRC Press


  • Introduces the analytical rate equations for basic one and two-step reactions relevant to the interactions of macromolecules with ligands.
  • Extends the analysis using the step-by-step approach of numerical integration and the "dice-rolling" approach of stochastic simulations.
  • Discusses the theory and practice of elucidating biomolecular mechanisms, including enzyme action, protein folding, protein-nucleic acid interactions and molecular motors.
  • Provides a comprehensive description of instruments and techniques for following transient reactions on a sub-second time scale and at the single-molecule level.
  • Illustrates the analysis of reaction records using computer simulation and fitting, using commercial software and freeware.
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