Prof. Bob Norman

Academic Director, College of Medicine, Biological Sciences and Psychology Dr Bob Norman

University of Leicester

Dr Bob NormanB.Sc. (Biological Sciences), Leicester, 1978
Ph.D. (Biochemistry), Imperial College, 1981
Diploma of Imperial College, 1981
M.I.Biol 1975
C.Biol 1984
FHEA 2002

PFHEA 2016

Tel: 0116 252 3777

Email: rin1@le.ac.uk

Address: Department of Medical and Social Care Education, University of Leicester, Leicester Medical School, Centre for Medicine, Lancaster Road, Leicester, LE1 7RH

Profile

Bob graduated from the University of Leicester with a BSc in Biological Sciences in 1978. He was awarded a PhD from Imperial College, London, in 1981 for his work on the molecular characterisation of the nicotinic acetylcholine receptor. He then moved to the Université de Nice, France, as an EMBO Fellow, to work on the molecular characterisation of a variety of cation channel proteins. He returned to the University of Leicester in 1983 and joined the staff as a temporary lecturer in the Department of Biochemistry, before being appointed to a lectureship in Medical Biochemistry in the Department of Medicine in 1984. Bob was promoted to Senior Lecturer in 1995. From 2007 to 2011 he was Deputy Head of the Department of Cardiovascular Sciences. Throughout this time, Bob’s research focused on the structure and regulation of cation channels, in particular the ATP-sensitive potassium channels in ventricular myocytes and vascular smooth muscle, including their role in ischaemic preconditioning. Bob has also worked on mechanisms underlying the development of essential hypertension, signalling perturbations associated with the development of urinary incontinence, and mechanisms of action of general anaesthetic agents.

In 2011, Bob transferred to the Department of Medical and Social Care Education at Leicester, as Director of Medical Education Research and Development, to develop research interests in medical education, and where he also led on quality management of the MBChB courses. In February 2014, Bob was appointed as Academic Director for the College of Medicine, Biological Sciences and Psychology, where he leads on strategy on all matters relating to undergraduate and postgraduate students and the delivery of teaching across the three Schools in the College. In this role he works with colleagues in the other Colleges to advance learning and teaching throughout the University. Bob has longstanding recognition as an educator in higher education becoming a Registered Practitioner of the Institute for Learning and Teaching in Higher Education, now the Higher Education Academy (HEA), in 2002, a Fellow of the HEA in 2007 and being recognised as a Principal Fellow of the HEA in 2016. His other distinctions include a University Teaching Fellowship (2006), a Society of Authors/Royal Society of Medicine Richard Asher Prize for his textbook, ‘Flesh and Bones of Medical Cell Biology’ (2008), and two awards from the University of Leicester Students’ Union; Academic of the Year (2009) and Students' Union Superstar (2015).

Current Research Interests

Student and staff use of intended learning outcomes

Improving feedback to medical students

Medical curriculum delivery by tablet computer, evaluation and development

Critical incident and no-harm incident reporting to inform rapid medical curriculum change

Factors influencing choices in medical careers

Student mental health at medical school

Structure and function of cardiac ATP-sensitive potassium channels

External Positions

Editor, BioMolecular Concepts 2009 to date

Chair, Chaplaincy Council, Chaplaincy to the University of Leicester 2000 to date

Editor, Cellular and Molecular Life Sciences 2000-2009

Editorial Adviser to the Biochemical Journal 1989-2010

Key Publications

Guraya SY, Norman RI, Roff S. Exploring the climates of undergraduate professionalism in a Saudi and a UK medical school. Medical Teacher 2016; 38: 630-632

Brennan S, Jackson R, Patel M, Sims MW, Hudman D, Norman RI, Lodwick D, Rainbow RD. Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection. Journal of Molecular and Cellular Cardiology. 2015; 79: 42–53.

Norman RI, Dogra N. A survey of the practice and experience of clinical educators in UK secondary care. BMC Medical Education.2014, 14: 229. doi/10.1186/1472-6920-14-229

Lodwick D*, Rainbow RD*, Rubaiy HN, Al Johi M, Vuister GW, Norman RISulphonylurea receptors regulate ATP-sensitive potassium channel pores via an inter-subunit salt bridge. Biochemical Journal. 2014; 464: 343-354. http://www.biochemj.org/bj/imps/abs/BJ20140273.htm

Dobbins K, Brooks S, Scott JJA, Rawlinson M and Norman RI. Understanding and enacting learning outcomes: the academic’s perspective. Studies in Higher Education  (CSHE-2014-0055) 2014 in press http://dx.doi.org/10.1080/03075079.2014.966668

Brooks S, Dobbins K, Scott JJA, Rawlinson M and Norman RI.Learning about learning outcomes: the student perspective. Teaching in Higher Education. 2014: 19(6): 721-733. http://dx.doi.org/10.1080/13562517.2014.901964

Sims M, Winter J, Brennan S, Norman R, Ng GA, Squire I and Rainbow R. PKC-mediated toxicity of elevated glucose concentration on cardiomyocyte function. American Journal of Physiology-Heart and Circulatory Physiology. 2014; 307(4): H587-H597. http://dx.doi.org/10.1152/ajpheart.00894.2013

Elliott, RA, Tonnu A, Ghaffar N, Taylor AH, Tincello DG, Norman RIEnhanced Purinergic Contractile Responses and P2X1 Receptor Expression in Detrusor Muscle during Cycles of Hypoxia-Glucopenia and Reoxygenation. Exp Physiol December 1, 2013 98 (12) 1683-1695

Turrell HE, Rodrigo GC, Norman RI, Dickens M, Standen NB.  Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPK.  J Mol Cell Cardiol. 2011 Sep;51(3):370-80. Epub 2011 Jun 26.

Rainbow RD, Norman RI, Everitt DE, Brignell JL, Davies NW, Standen NB. Endothelin and angiotensin II inhibit arterial voltage-gated K+ channels through different PKC isozymesCardiovasc Res. 2009 Aug 1;83(3):493-500.

Kang Y, Ng B, Leung YM, He Y, Xie H, Lodwick D, Norman RI, Tinker A, Tsushima RG, Gaisano HY. Syntaxin-1A actions on sulfonylurea receptor 2A can block acidic pH-induced cardiac K(ATP) channel activation. J Biol Chem. 2006 Jul 14;281(28):19019-28.

Rainbow RD, Norman RI, Hudman D, Davies NW, Standen NB. Reduced effectiveness of HMR 1098 in blocking cardiac sarcolemmal K(ATP) channels during metabolic stress. J Mol Cell Cardiol. 2005 Oct;39(4):637-46.

Van Beever L, Poitry S, Faure C, Norman RI, Roatti A, Baertschi AJ. Pore loop-mutated rat KIR6.1 and KIR6.2 suppress KATP current in rat cardiomyocytes. Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H850-9.

R D Rainbow, D Lodwick, D Hudman, N W Davies, R I Norman, N B Standen. SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes. J. Physiol. 2004; 557:785-794.

Books

R.I. Norman and D. Lodwick. Medical Cell Biology Made Memorable. Churchill Livingstone (1999) 195 pages.

R.I. Norman and D. Lodwick. Flesh and Bones of Medical Cell Biology. Mosby (2007) 124 pages. Award winner at Royal Society of Medicine Book Awards, 2008

Flesh & Bones of Medical Cell Biology
Flesh and Bones of Medical Cell Biology. Winner at Royal Society of Medicine Book Awards, 2008.
Drs Lodwick & Norman
Drs Norman and Lodwick receiving their award from Alexander MacCall Smith. (Photo: Matt Crossick)

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Contact

University of Leicester Medical School
Centre for Medicine
Lancaster Road
Leicester
LE1 7HA

Admissions: 0116 252 2969/2966/2985/3015
Student Records: 0116 252 2969
Student Enquiries Desk: 0116 252 3021
Bequest Secretary: 0116 252 3082

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