Return to Profile page

Publications for last 10 years only 

2013  2012  2011  2010  2009 2003-2008 




Muangman S, Korbsrisate S, Muangsombut V, Srinon V, Adler NL, Schroeder GN, Frankel G, Galyov EE. BopC is a type III secreted effector protein of Burkholderia pseudomallei. FEMS Microbiol Lett 2011;323(1):75-82

Lazar Adler NR, Stevens JM, Stevens MP, Galyov EE. Autotransporters and their role in the virulence of Burkholderia pseudomallei and Burkholderia mallei. Front Microbiol 2011;2:151

Gatedee J, Kritsiriwuthinan K, Galyov EE, Shan J, Dubinina E, Intarak N, Clokie MR, Korbsrisate S. Isolation and characterization of a novel podovirus which infects Burkholderia pseudomallei. Virol J 2011;8:366

Tippayawat P, Pinsiri M, Rinchai D, Riyapa D, Romphruk A, Gan YH, Houghton RL, Feigner PL, Titball RW, Stevens MP, Galyov EE, Bancroft GJ, Lertmemonkolchai G. Burkholderia pseudomallei proteins presented by monocyte-derived dendritic cells stimulate human memory T cells in vitro Infect Immun 2011;79(1):305-13


Galyov EE, Brett PJ, Deshazer D. Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis. Annu Rev Microbiol 2010;64:495-517

Layton AN, Hudson DL, Thompson A, Hinton JC, Stevens JM, Galyov EE, Stevens MP. Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in Salmonella enterica serovar Typhimurium is associated with iron restriction and can be reversed by free iron. FEMS Microbiol Lett 2010;302(2):114-22



Field TR, Layton AN, Bispham J, Stevens MP, Galyov EE. Identification of novel genes and pathways affecting Salmonella T3SS-1 using a contact-dependent haemolysis assay. J Bacteriol 2008;190(9):3393-8

Upadhyay A, Wu HL, Williams C, Field T, Galyov EE, van den Elsen JM, Bagby S. Guanine nucleotide exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42. Biochem J 2008;411(3):485-93

Wall DM, Nadeau WJ, Pazos MA, Shi HN, Galyov EE, McCormick BA. Identification of the Salmonella enterica serotype Typhimurium SipA domain responsible for inducing neutrophil recruitment across the intestinal epithelium. Cell Microbiol 2007;9(9):2299-313.

Layton AN, Galyov EE. Salmonella-induced enteritis: molecular pathogenesis and therapeutic implications. Expert Rev Mol Med 2007;9(18):1-17. Review.

Hudson DL, Layton AN, Field TR, Bowen AJ, Wolf-Watz H, Elofsson M, Stevens MP, Galyov EE. Inhibition of type III secretion in Salmonella enterica serovar Typhimurium by small-molecule inhibitors. Antimicrob Agents Chemother 2007;51(7):2631-5.

Johnson S, Roversi P, Espina M, Olive A, Deane JE, Birket S, Field T, Picking WD, Blocker AJ, Galyov EE, Picking WL, Lea SM. Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J Biol Chem 2007;282(6):4035-44.

Zhao C, Wood MW, Galyov EE, Höpken UE, Lipp M, Bodmer HC, Tough DF, Carter RW. Salmonella typhimurium infection triggers dendritic cells and macrophages to adopt distinct migration patterns in vivo. Eur J Immunol 2006;36(11):2939-50.

Haque A, Chu K, Easton A, Stevens MP, Galyov EE, Atkins T, Titball R, Bancroft GJ. A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins. J Infect Dis 2006;194(9):1241-8.

Roversi P, Johnson S, Field T, Deane JE, Galyov EE, Lea SM. Expression, purification, crystallization and preliminary crystallographic analysis of BipD, a component of the Burkholderia pseudomallei type III secretion system. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006;62(9):861-4.

Stevens JM, Galyov EE, Stevens MP. Actin-dependent movement of bacterial pathogens. Nat Rev Microbiol 2006;4(2):91-101. Review.

Dukes JD, Lee H, Hagen R, Reaves BJ, Layton AN, Galyov EE, Whitley P. The secreted Salmonella dublin phosphoinositide phosphatase, SopB, localizes to PtdIns(3)P-containing endosomes and perturbs normal endosome to lysosome trafficking. Biochem J 2006;395(2):239-47.

Ungewickell A, Hugge C, Kisseleva M, Chang SC, Zou J, Feng Y, Galyov EE, Wilson M, Majerus PW. The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases. Proc Natl Acad Sci USA 2005;102(52):18854-9.

Stevens JM, Ulrich RL, Taylor LA, Wood MW, Deshazer D, Stevens MP, Galyov EE. Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutant. J Bacteriol 2005;187(22):7857-62.

Layton AN, Brown PJ, Galyov EE. The Salmonella translocated effector SopA is targeted to the mitochondria of infected cells. J Bacteriol 2005;187(10):3565-71.

Stevens MP, Stevens JM, Jeng RL, Taylor LA, Wood MW, Hawes P, Monaghan P, Welch MD, Galyov EE. Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei. Mol Microbiol 2005;56(1):40-53.

Williams C, Galyov EE, Bagby S. Solution structure, backbone dynamics, and interaction with Cdc42 of Salmonella guanine nucleotide exchange factor SopE2. Biochemistry 2004;43(38):11998-2008.

Huang FC, Werne A, Li Q, Galyov EE, Walker WA, Cherayil BJ. Cooperative interactions between flagellin and SopE2 in the epithelial interleukin-8 response to Salmonella enterica serovar typhimurium infection. Infect Immun 2004;72(9):5052-62.

Stevens MP, Haque A, Atkins T, Hill J, Wood MW, Easton A, Nelson M, Underwood-Fowler C, Titball RW, Bancroft GJ, Galyov EE. Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology 2004;150:2669-76.

Stevens MP, Galyov EE. Exploitation of host cells by Burkholderia pseudomallei. Int J Med Microbiol 2004;293:549-55. Review.

Upadhyay A, Williams C, Gill AC, Philippe DL, Davis K, Taylor LA, Stevens MP, Galyov EE, Bagby S. Biophysical characterization of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. Biochim Biophys Acta 2004;1698:111-9.

Wu HL, Williams C, Upadhyay A, Galyov EE, Bagby S. Assignment of the 1H, 13C and 15N resonances of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei. J Biomol NMR 2004;29:215-6.

Stevens MP, Friebel A, Taylor LA, Wood MW, Brown PJ, Hardt WD, Galyov EE. A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J Bacteriol 2003;185:4992-6.

Williams C, Galyov EE, Bagby S. Assignment of the 1H, 13C and 15N resonances of the catalytic domain of guanine nucleotide exchange factor SopE2 from Salmonella dublin. J Biomol NMR 2003;26:379-80

Share this page:

Contact Details

Department of Respiratory Sciences
Maurice Shock Medical Sciences Building
University Road
Leicester LE1 9HN

Head of Department: Professor Mike Barer

PA: Alison Brown

General enquiries

T:+44 (0)116 252 2951