Dr Emma Watson

I am a Kidney Research UK Post-doctoral Research Fellow. My research interests focus around the improvement of physical function and quality of life through exercise interventions or nutrients. In particular I am interested in the mechanisms that drive muscle wasting and cause fatigue, which are common in CKD, but are under-researched. They important clinical problems as they are strongly associated with increased morbidity and mortality and are modifiable risk factors to help prevent CVD, the most common cause of premature death in this population.

Research Interests

The focus of my research interests are on:

  • Signalling to protein synthesis and protein degradation
  • Muscle satellite cell activation and muscle repair
  • Intramuscular inflammation
  • MicroRNA expression in skeletal muscle
    Iron therapy and mitochondrial function
  • Development of intramuscular fibrosis
  • The role of exercise in the management of CKD and as potential therapy to slow or reverse muscle wasting.

Techniques and skills:

    • Muscle biopsy processing and handling
    • Western Blotting
    • PCR
    • HPLC
    • Immunohistochemistry
    • Flow cytometry
    • Cell culture
    • Isotope work

Contact: ec174@leicester.ac.uk

Award

  • 2018 Early Career Award
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