Social and Epidemiological Psychiatry

Social and Epidemiological Psychiatry Overview

The Social & Epidemiological Psychiatry Research Group consists of two interrelated research areas in adult mental health and disability (Professor Brugha), and in the psychiatry of older people (Dr Velayudhan and Emeritus Professor Lindesay). The group conducts substantive, applied and methodological research. The Group is closely allied with other research groups within the Department of Health Sciences with growing links with the Department of Psychology. The group also makes a substantial contribution to survey Secondary Analysis Collaborations with strong links to other academic institutions throughout the world. Long-term collaborations are maintained with the following universities: Cambridge (England); the Institute of Psychiatry (London), Bristol, Sheffield, Groningen, Harvard.

The group has been able to lead on the solution to substantive research questions with its collaborations with external and world class expertise in survey methods and instrument development and evaluation, developmental psychopathology and social care, adult psychopathology and social influences on health, mental health promotion and mental disorder prevention, developmental psychology, criminology and the psychology of delinquency, drug misuse and crime, ageing and memory, suicide and deliberate self harm; and across the group long standing relationships and firsthand experience in policy information research in British and EU Government settings.

The group also offers a SCAN (Schedules for Clinical Assessment in Neuropsychiatry Version 2.1) Training Course twice a year in collaboration with local NHS partners.

Professor Terry Brugha is presently the lead investigator on the first ever-large scale epidemiological survey of autism spectrum disorders in adults, is chair of the WHO Advisory Committee of SCAN, and leads a programme of observational and experimental research into the prevention of depression in women in the context of child birth. He is associate editor of Psychological Medicine. Previous positions have included joint co-ordinator of the WHO World Mental Health Survey initiative in Europe (ESEMED) and Secretary General of the International Federation for Psychiatric Epidemiology.

Members of the group are currently carrying out research on the prevalence of autistic spectrum conditions (ASC) in adults living in communal care establishments and those with learning disabilities, funded by the NHS Information Centre for Health and Social Care. Results from this study will be combined with information from the 2007 Adult Psychiatric Morbidity Survey [1] to estimate the overall prevalence of ASC in adults living in England.  Please click here for a copy of the protocol and here for an easy read version

[1] Brugha, T., McManus, S., Meltzer, H. et al (2007) Autism Spectrum Disorders in adults living in households throughout England. Report from the adult psychiatric morbidity survey 2007. The NHS Information Centre for Health and Social Care, England.

Dr Latha Velayudhan’s current research involves establishing biomarkers for Alzheimer’s disease conversion, progression and treatment response using different approaches: clinical test using smell identification test and laboratory based tests for plasma protein markers. She is associate editor of Journal of Alzheimer’s Disease.

Further research activity is carried out in the psychopathological and psychosocial aspects of mental disorders in late life, particularly the dementias, depression and anxiety; suicide and self-harm; screening for depression in palliative care; assistive technologies for dementia (with the Trent Dementia Services Development Centre); and clinical trials of service developments in collaboration with the NHS, in particular Leicestershire Partnership NHS Trust

The group are also part of a collaboration of UK centres involved in the design and execution of large-scale independent clinical trials in dementia (MADE http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=14866, RADAR http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=15071, AFFECT http://www.alzheimers.org.uk/vasculartrial ).

Together with the Department of Genetics, and colleagues from Loughborough, Warwick and Aston, this research area forms part of the recently-established Midlands Centre of the Alzheimer’s Research Trust’s national Network of dementia research groups.

The Group’s staff includes two senior research fellows, two statisticians and is closely linked with a lecturer in the CLAHRC project and a clinical lecturer in psychiatry.

 

 

 

People

For general enquiries, please email hsenquiries@leicester.ac.uk or telephone +44 (0)116 252 5402.

Research Group Lead

Name E-mail Telephone (0116) Room
Prof Terry Brugha tsb@le.ac.uk 252 3202 CFM 3.42

Research Staff

Name E-mail Telephone (0116) Room
Zoe Morgan zlm2@le.ac.uk 252 6233 CFM 4.38

Administrative Staff

Name E-mail Telephone (0116) Room
Sabiha Akhanji saa74@le.ac.uk

Honorary Staff

Name Email Title
Mohammed Al-Uzri mmau1@le.ac.uk Hon. Professor
Prof Sab Bhaumik --- Hon Professor
Nandini Chakraborty --- Hon Senior Lecturer
Prof James Lindesay jebl1@le.ac.uk Emeritus Professor
Richard Prettyman richard.prettyman@leicspart.nhs.uk Hon Senior Lecturer
Sam Tromans sjt56@le.ac.uk

Hon Academic Clinical Lecturer

Research Group Associates

Name Email Organisation
Prof Alex Mitchell
ajm80@le.ac.uk
Department of Cancer Studies, University of Leicester

Publications

2008 onwards publications are available on individual staff pages from People link.

2007

  1. Alonso J; Codony M, Kovess V, Angermeyer MC Katz SJ, Haro JM, De Girolamo G, De Graaf R, Demyttenaere K, Vilagut G, Almansa J, Lepine JP, Brugha TS. Population level of un met need for mental healthcare in Europe. British Journal of Psychiatry 2007;190:299-306.
  2. Brugha T. Who should own Public Mental Health? International Journal of Public Health 2007;52:1-2.
  3. Coid J, Yang M Roberts A, Ullrich S, Moran P, Bebbington P, Brugha T, Jenkins R, Farrell M, Singleton R. Authors' reply British Journal of Psychiatry 2007;190:177-178.
  4. Cooke DD, Newman SP, Sacker A, Devellis B, Bebbington P, Meltzer H. The impact of physical illnesses on non-psychotic psychiatric morbidity: data from the household survey of psychiatric morbidity in Great Britain. British Journal of Health Psychology 2007;12:3:463-71. Social & Epidemiological Psychiatry 77
  5.  Dennis M, Baillon S, Brugha T, Lindesay J, Stewart R, Meltzer H. The spectrum of suicidal ideation in Great Britain: comparisons across a 16-74 years age range. Psychological Medicine 2007;37:6:795-805.
  6.  Fear NT, Iversen A, Meltzer H, Workman L, Hull L, Greenberg N, Barker C, Browne T, Earnshaw M, Horn O, Jones M, Murphy D, Rona R, Hotopf M, Wessely S. Patterns of drinking in the UK Armed Forces Addiction 2007;102:11:1749-59.
  7. Fernandez A, Haro JM, Martinez-Alonso M, Demyttenaere K, Brugha TS, Autonell J, de Girolamo G, Bernert S, Lepine JP, Alonso J. Treatment adequacy for anxiety and depressive disorder in six European countries, British Journal of Psychiatry 2007;190:172-173.
  8.  Ford T, Vostanis P, Meltzer H, Goodman R. Psychiatric disorder among British children looked after by local authorities: comparison with children living in private households. British Journal of Psychiatry 2007;190:4:319-325.
  9. Heider D, Angermeyer MC, Winkler I, Schomerus G, Bebbington PE, Brugha T, Azorin JM, Toumi A. A prospective study of Quality of Life in schizophrenia in three European countries. Schizophrenia Research 2007;93:1-3:194-202.
  10. Jordanova V, Stewart R, Goldberg D, Bebbington PE, Brugha T, Singleton N, Lindesay J, Jenkins R, Prince M, Meltzer H. Age variation in life events and their relationship with common mental disorders: An analysis of data from 16-74 year old participants in the 2000 National Survey of Psychiatric Morbidity in Great Britain. Social Psychiatry and Psychiatric Epidemiology 2007;42:611-616. Social & Epidemiological Psychiatry 78
  11. Kovess-Masfety V, Alonso J, Brugha TS, Angermeyer MC, Haro JM, Sevilla-Dedieu C. Differences in lifetime use of services for mental health problems in six European countries. Psychiatric Services: Journal of the American Psychiatric Association 2007;58:2:213-220.
  12. Meltzer H, Vostanis P, Goodman R, Ford T. Children‟s perceptions of neighbourhood trustworthiness and safety and their mental health. Journal of Child Psychology and Psychiatry 2007;48:12:1208-13.
  13. Meltzer H. Childhood mental disorders in Great Britain: an epidemiological perspective. Child Care in Practice 2007;13:4:313-26,
  14. Moran P, Stewart R, Brugha T, Bebbington P, Bhugra D, Jenkins R, Coid JW. Personality disorder and cardiovascular disease: results from a national household survey. Journal of Clinical Psychiatry 2007;68:1:69-74.

  15. Lee, D, Morgan, K., & Lindesay, J. (2007)  Impact of institutional respite care on the sleep quality of people with dementia and their primary caregivers.  Journal of the American Geriatrics Society, 55, 252-258.
  16. Dennis M, Baillon S, Brugha T, Lindesay J, Stewart R, & Meltzer H.  (2007) The spectrum of suicidal ideation in Great Britain: comparisons across a 16-74 age range.  Psychological Medicine. 37; 795-806. Doi:10.1017/S0033291707000013
  17. Malone, D., & Lindesay, J.  (2007)  Cholinesterase inhibitors and cardiovascular disease: a survey of psychiatrists’ practice.  Age & Ageing , 36, 331-333
  18.  Jordanova, V., Stewart, R., Goldberg, D., Bebbington, P.E., Brugha, T., Singleton, N., Lindesay, J., Jenkins, R., Prince, M., & Meltzer, H.  (2007)  Age variation in life events and their relationship with common mental disorders: An analysis of data from 16-74 year old participants in the 2000 National Survey of Psychiatric Morbidity in Great Britain.  Social Psychiatry and Psychiatric Epidemiology, 42, 8, 611-616. 

  19. Dennis M, Wakefield P, Molloy C, Andrews H, & Friedman T. A study of self-harm in older people: mental disorder, social factors and motives. Aging & Mental Health, 11, 5, 520-525

  20. Subramanian H, Dennis M, & Byrne J. The role of vascular risk factors in late onset bipolar disorder.  In press International Journal of Geriatric Psychiatry, Doi:10.1002/gps.1730.

 

2006

  1. Coid J, Yang M, Roberts A, Ullrich S, Moran P, Bebbington P, Brugha T, Jenkins R, Farrell M, Lewis G and Singleton N. Violence and psychiatric morbidity in the national household population of Britain: public health implications . Br J Psychiatry. 2006;189 12-19.
  2. Coid J, Yang M, Roberts A, Ullrich S, Moran P, Bebbington P, Brugha T, Jenkins R, Farrell M, Lewis G and Singleton N. Violence and psychiatric morbidity in a national household population – A report from the British Household Survey. Br J Psychiatry. 2006 Oct 10. ( EPub)
  3. Farrell M, Boys A, Singleton N, Meltzer H, Brugha T, Bebbington P, Jenkins R, Coid J, Lewis G, Marsden J. Predictors of mental health service utilization in the 12 months before imprisonment: analysis of results from a national prisons survey, (2006) Aust N Z J Psychiatry Jun-Jul;40(6-7):548-53.
  4. Lindesay J, Baillon S, Brugha T, Dennis M, Stewart R, Araya R and Meltzer H. Worry content across the lifespan: An analysis of 16-74 year old participants in the British National Survey of Psychiatric Morbidity 2000. Psychological Medicine. 2006;36:11:1625-1634.
  5. Messer J, Goodman R, Rowe R, Meltzer H, Maugham B. Pre-adolescent conduct problems in girls and boys. Journal of the American Academy of Child and Adolescent Psychiatry, 2006;45:2:184-191.
  6. Torres, AR, Moran P, Bebbington P, Brugha T, Bhugra D, Coid J, Farrell M, Jenkins R, Lewis G, Meltzer H and Prince M. Obsessive-compulsive disorder and Personality Disorder. Evidence from the British National Survey of Psychiatric Morbidity 2000. Social Psychiatry and Psychiatric Epidemiology. 2006 (Epub Sep15)
  7. Torres, A.R., Prince, M.J. Bebbington, P.E., Bhugra, D., Brugha, T.S., Farrell, M., Jenkins, R., Lewis, G., Meltzer, H. & Singleton, N. (2005). Obsessive-compulsive disorder: prevalence, comorbidity, impact and help-seeking in the UK National Psychiatric Morbidity Survey of 2000. American Journal of Psychiatry, 163:11, 1978-85
  8. Wiles NJ, Zammit S, Bebbington P, Singleton N, Meltzer H, Lewis G. Self-reported psychotic symptoms in the general population: results from the longitudinal study of the British National Psychiatric Morbidity Survey. Br J Psychiatr,. 2006;188:519-26.
  9. Simpson, R., Wakefield, P., Spiers, N., Jagger, C. & Lindesay, J.  (2006)  Carer held records for dementia: a controlled trial.  International Psychogeriatrics, 18, 259-68. 
  10. Lindesay, J., Baillon, S., Dennis, M., Brugha, T., Stewart, R., Araya, R., & Meltzer, H.  (2006)  Worry content across the lifespan: An analysis of 16-74 year old participants in the United Kingdom 2000 National Survey of Psychiatric Morbidity.  Psychological Medicine 36, 1625-1634.  
  11. Parker, S.G., Bechinger-English, D., Jagger, C., Spiers, N. & Lindesay, J. (2006)  Factors affecting completion of the SF-36 in older people.  Age and Ageing , 35, 376-81. 
  12. Stewart, R., Besset, A., Bebbington, P., Brugha, T., Lindesay, J., Jenkins, R., Singleton, N, & Meltzer, H. (2006)  Age and insomnia: risk factors, impact and hypnotic use in 16-74 year olds from a national survey population.  Sleep, 29, 1391-7. 
  13. Mitchell A, & Dennis M.  (2006) Self-harm and attempted suicide in adults: 10 practical questions and answers for emergency department staff.  Emergency Medicine Journal. 23: 251-255.

 

2005

  1. Antonioli C, Reveley MA. Randomised controlled trial of animal facilitated therapy with dolphins in the treatment of depression. BMJ 2005;331:7527:1231-34.
  2. Brugha TS, Jenkins R, Bebbington PE, Lewis G, Fryers T, Farrell M, Coid J, Melzer D, Singleton N, Meltzer H. Psychosis in the community and in prison: a report from the National Survey of Psychiatric Morbidity. Am. J. of Psychiatry.2005;162(4):774-780.
  3. Brugha TS, Meltzer H, Jenkins R, Bebbington PE, Taub NA.Comparison of the CIS- R and CIDI Lay diagnostic interviews for anxiety and depression disorders. Psychol Med. 2005;07-Jul:35:7:1089-1091.
  4. Brugha TS, Weich S, Singleton N, Lewis G, Bebbington PE,Jenkins R, Meltzer H. Primary group size, social support, gender and future mental health status in a prospective study of people living in private households throughout Great Britain. Psychological Medicine. 2005;35:705-714.
  5. Dunkley MJ, Reveley MA. Successful treatment of refractory schizophrenia with combined olanzapine and quetiapine in a patient with a prolactin secreting pituitary microadenoma.Journal of Psychopharmacology. 2005;19:97-101.
  6. Jenkins R, Bhugra D, Meltzer H, Singleton N, Bebbington P, Brugha T, Coid J, Farrell M, Lewis G, Paton J. Psychiatric and social aspects of suicidal behaviour in prisons. Psychological Medicine. 2005;35:257-270.
  7.  Moran PM, Owen L, Al-Uzri MM, Reveley MA Dissociable effects of typical and atypical antipsychotic drugs on a salience attribution strategy that mediates slower visuospatial associative learning in schizophrenia. International Journal of Neuropsychopharmacology 2005;7:S396:Suppl. 1.
  8. Moran PM, Owen L, Al-Uzri MM, Reveley MA. An association between kamin blocking and negative and depression-related symptoms in schizophrenia. Journal of Psychopharmacology. 2005;19:5:Suppl.A14.
  9. Roberts EO, Proudlock FA, Gottlob I, Reveley MA. Eye movements in schizophrenia and reading. Investigative Opthalmology and Visual Science 2005;46:2942:Suppl. S.
  10. Taub NA, Morgan Z, Brugha TS, Lambert PC, Bebbington PE, Jenkins R, Kessler RC, Zaslavsky AM, Hotz T. Recalibration  methods to enhance information on prevalence rates from large mental health surveys. International J. of Methods in Psychiatric Research. 2005;14(1):3-13
  11. Baillon, S., van Diepen, E., Prettyman, R., Rooke, N., Redman, J. & Campbell, R. (2005) Variability in response of older people with dementia to both Snoezelen and reminiscence. British Journal of Occupational Therapy. 68(8), 367-374.

  12. van Diepen, H., Baillon, S., Prettyman, R., Redman, J., Scarborough, C. & Kamm, T. (2005) (Abstract) Pilot study of the effects of multi-sensory treatment therapy on elderly patients suffering from depression. International Psychogeriatrics, 17 Supp 2, S362.

  13. Dennis, M., Baillon, S., Brugha, T., Lindesay, J. & Meltzer, H. (2005) (Abstract) The spectrum of suicidal ideation in later life.  A population survey of Great Britain.  International Psychogeriatrics, 17 (Supp 2), S380.

  14. Dennis M.  (2005) Other causes of dementia.  Psychiatry,4:1, 62-64

  15. Suribhatla S, Dennis M, & Potter J.  (2005) A study of statin use in the prevention of cognitive impairment of vascular origin in the UK.  Journal of the Neurological Sciences, 229-230, 147-150.

  16. Dennis M, Wakefield P, Molloy C, Andrews H, & Freidman, T.  (2005) Self-harm in older people with depression: a comparison of social factors, life events and symptoms. British Journal of Psychiatry, 186, 538-9.

  17. Malone D, & Dennis M.  (2005) Multiple system atrophy and hallucinations – a short report.  International Journal of Geriatric Psychiatry, 20, 699-700.

  18. Owens D, Wood C, Greenwood D, Hughes T, & Dennis M.  (2005) Mortality and suicide after non-fatal self-poisoning: a 16-year outcome study of patients attending accident and emergency.  British Journal of Psychiatry, 187, 470-475.

 

Research Projects

Research Overview

Members of the group are currently carrying out research on the prevalence of autistic Psychiatry - Projects Imagespectrum conditions (ASC) in adults living in communal care establishments and those with learning disabilities, funded by the NHS Information Centre for Health and Social Care. Results from this study will be combined with information from the 2007 Adult Psychiatric Morbidity Survey [1] to estimate the overall prevalence of ASC in adults living in England.

[1] Brugha, T., McManus, S., Meltzer, H. et al (2007) Autism Spectrum Disorders in adults living in households throughout England. Report from the adult psychiatric morbidity survey 2007. The NHS Information Centre for Health and Social Care, England.

Please click here for a copy of the protocol and here for an easy read version

Further research activity is carried out in the psychopathological and psychosocial aspects of mental disorders in late life, particularly the dementias, depression and anxiety; suicide and self-harm; screening for depression in palliative care; assistive technologies for dementia (with the Trent Dementia Services Development Centre); and clinical trials of service developments in collaboration with the NHS, in particular Leicestershire Partnership NHS Trust

The group are also part of a collaboration of UK centres involved in the design and execution of large-scale independent clinical trials in dementia (MADE http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=14866, RADAR http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=15071, AFFECT http://www.alzheimers.org.uk/vasculartrial ).

Together with the Department of Genetics, and colleagues from Loughborough, Warwick and Aston, this research area forms part of the recently-established Midlands Centre of the Alzheimer’s Research Trust’s national Network of dementia research groups.

Current Research

  • Observational study of resource use and cost of Alzheimer's disease in Europe (GERAS) - a multi-centre project funded by Eli Lilly
  • Smell identification function as a treatment response marker and progression marker in Alzheimer's disease.
  • Clinical imaging markers in Alzheimer's disease (in collaboration with Institute of Psychiatry, London and Nottingham University).
  • Longitudinal outcome in people assessed in Younger Person's Memory Service.
  • Screening for depression using the Edinburgh Depression Rating Scale in older adults in an acute general hospital setting.

Past Postgraduate Research Projects

  • Sarah Baillon - The performance of the Edinburgh Depression Rating Scale as a screening tool for depression in Parkinson’s disease.

Recent Research

  • Secondary analysis of ONS Psychiatric Morbidity Survey Data from 2000:
    • the relationship between age, worry content, common mental disorders and functional limitation.
    • the relationship between age, suicidal ideation and common mental disorder, and the influence of limitation in activities of daily living on suicidal ideation.
  • An evaluation of nurse-led computer-assisted patient assessment and diagnosis in the memory clinic (a collaboration with Loughborough University).
  • A multi-centre MRC funded project - Donepezil and Memantine in moderate to severe Alzheimer’s disease (DOMINO-AD).
  • A survey of all in-patient admissions in Mental Health Services for Older People over a six month period.
  • Personality disturbance in older adults with depression and self harm: a case control study.
  • A definitive multi-centre pragmatic randomised controlled trial of clinical and cost effectiveness of mirtazipine and sertraline versus placebo for the treatment of depression in dementia presenting in secondary care (HTA-SADD).
  • A systematic review of the outcome of deliberate self harm in older people (a collaboration with Leeds University).
  • A caseload weighting scale for use by community psychiatric nurses in community mental health teams (CMHTs) for older people.
  • A randomised controlled trail of a cholinesterase inhibitor in the management of agitation in dementia that is unresponsive to psychological intervention (CALM-AD Trial).

Social & Epidemiological Psychiatry

The Social & Epidemiological Psychiatry Research Group consists of two interrelated research areas in adult mental health and disability (Professor Brugha), and in the psychiatry of older people (Dr Velayudhan and Emeritus Professor Lindesay). The group conducts substantive, applied and methodological research. The Group is closely allied with other research groups within the Department of Health Sciences with growing links with the Department of Psychology. The group also makes a substantial contribution to survey Secondary Analysis Collaborations with strong links to other academic institutions throughout the world. Long-term collaborations are maintained with the following universities: Cambridge (England); the Institute of Psychiatry (London), Bristol, Sheffield, Groningen, Harvard.

The group has been able to lead on the solution to substantive research questions with its collaborations with external and world class expertise in survey methods and instrument development and evaluation, developmental psychopathology and social care, adult psychopathology and social influences on health, mental health promotion and mental disorder prevention, developmental psychology, criminology and the psychology of delinquency, drug misuse and crime, ageing and memory, suicide and deliberate self harm; and across the group long standing relationships and firsthand experience in policy information research in British and EU Government settings.

The group also offers a Schedules for Clinical Assessment in Neuropsychiatry (SCAN) Version 2.1 Training Course twice a year in collaboration with local NHS partners.

Button - People
Button - Projects
Button - Grants & Awards
Button - SCAN

Share this page:

Group Lead

Prof. Terry Brugha
+44(0) 116 252 3211
tsb@le.ac.uk

Contact Us

Department of Health Sciences
University of Leicester
George Davies Centre
University Road
Leicester
LE1 7RH
United Kingdom

Tel: +44 (0) 116 252 3211

Head of Department:
Prof. Graham Martin

Other Key People

Twitter

Accessibility

DisabledGo logo

The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Centre for Medicine.