Olivia Leavy

Postdoctoral Research Associate in Genetic Epidemiology

CONTACT DETAILS

Department of Health Sciences
University of Leicester
George Davies Centre
University Road
Leicester LE1 7RH

Tel: 00 44 116 229 7208

Email: ocl3@leicester.ac.uk

Personal Details

I have a BSc in Mathematics and Statistics (Oxford Brookes University) and an MSc in Medical Statistics (Oxford Brookes University).

I undertook a PhD in Genetic Epidemiology at the London School of Hygiene and Tropical Medicine (LSHTM), under the supervision of Prof Frank Dudbridge. My PhD focussed on better understanding the genetic architecture of breast cancer and was funded by Breast Cancer Now.

I then worked as a research assistant at LSHTM as part of the FORECEE project, which focussed on developing a risk prediction tool for breast, ovarian, cervical and endometrial cancer.

Research

I am a postdoctoral researcher and my research focusses on better understanding the genetic basis of susceptibility to idiopathic pulmonary fibrosis (IPF), a chronic lung disease that results in scarring of the lungs. There is currently no cure for IPF and the median survival time after diagnosis is 3 years. My research aim is to undertake research that will improve our knowledge of IPF and aid in the development of new treatments for the disease.

I have experience analysing large scale genetic data, epigenetic data (DNA methylation data) and Capture Hi-C data.

ORCHID ID: https://orcid.org/0000-0002-1503-5535

Publications

Leavy OC, et al. Proportion of idiopathic pulmonary fibrosis risk explained by known genetic loci. medRxiv: https://www.medrxiv.org/content/10.1101/2020.08.14.20172528v1. 2020.  

Tang W, Saratzis A, Pattee J, Smith J, Pankratz N, Leavy OC, et al. Replication of newly identified genetic associations of abdominal aortic aneurysm with SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG. European Journal of Vascular and Endovascular Surgery. 2020.

Baxter J.*, Leavy OC*, Dryden NH*, et al. Capture Hi-C analysis of 63 breast cancer loci identifies putative target genes and causal variants. Nature Communications. 2018.     * joint first authors

Rydén AS, Leavy OC, Halling K, Stone AA. Comparison of daily vs. weekly recording of gastroesophageal reflux disease (GERD) symptoms in patients with a partial response to proton pump inhibitor (PPI) therapy. Value in Health. 2016.

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