David R Jones

Emeritus Professor of Medical Statistics

David Jones

 

CONTACT DETAILS

Email: drj@le.ac.uk

Please use the above email address to contact me in the first instance as I no longer visit the Department regularly and frequently.

 

 

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Research Interests

Research Projects

Selected Publications

 

RESEARCH INTERESTS:

Several aspects of the methodology of health services and public health research and clinical trials, including

  • Extensions of systematic review and meta-analysis methods to include diverse sources of evidence,
  • Methods for monitoring professional performance, and
  • Application of Bayesian methods

 

RESEARCH PROJECTS

My current projects include i) investigation of methods for combining epidemiological and toxicological data, ii) methodological aspects of risk assessment, iii) meta-analyses in various areas, and iv) value of information methods in public health and other application areas.

 

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SELECTED PUBLICATIONS

For access to supplementary materials please click here.

For a note on the ORACLE Children Study data sharing policy, please click here

 

  • Achana F, Sutton AJ, Kendrick D,Hayes M, Jones DR, Hubbard SJ, Cooper NJ. A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health 2016; in press.

  • Marlow N, Bower H, Jones DR, Brocklehurst P, Kenyon S, Pike K, Taylor D, Salt A. The ORACLE Children Study: Educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. Arch Dis Childhood 2016; in press.

  • Baker R , Honeyford K , Levene LS , Mainous AG 3rd, Jones DR, Bankart MJ, Stokes T.  Population characteristics, mechanisms of primary care and premature mortality in England: A cross-sectional study. BMJ Open 2016; 6: e009981. doi: 10.1136/bmjopen-2015-009981.
  • Achana F, Sutton AJ, Kendrick D, Wynn P, Young B, Jones DR, Hubbard SJ, Cooper NJ. The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis. PLOS One 2015;10.1371/journal.pone.0121122

  • Honeyford C, Baker R, Bankart MJG, Jones DR. Estimating smoking prevalence in general practice using data from the Quality and Outcomes Framework (QOF) BMJ Open 2014;4:e005217 doi:10.1136/bmjopen-2014-005217

  • Hubbard SJ, Cooper NJ, Kendrick D, Young B Wynn PM, He Z, Miller P, Jones DR, Achana FA, Sutton AJ. Network meta-analysis to evaluate the effectiveness of interventions to prevent falls in children under age 5 years. Injury Prevention 2014 doi:10.1136/injuryprev-2013-041135

  • Achana FA, Cooper NJ, Bujkiewicz S, Hubbard SJ, Kendrick D, Jones DR, Sutton AJ. Network meta-analysis of multiple outcome measures accounting for borrowing of information across outcomes. BMC Medical Research Methodology 2014, 14:92. doi: 10.1186/1471-2288-14-92. See http://www.biomedcentral.com/1471-2288/14/92

  • Honeyford C, Baker R, Bankart MJG, Jones DR.  Modelling factors in primary care quality improvement: a cross-sectional study of premature CHD mortality.  BMJ Open 2013; 3.  doi: 10.1136/bmjopen-2013-003391.

  • Pike K, Brocklehurst P, Jones DR, Kenyon S, Salt A, Taylor D, Marlow N. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: The ORACLE Children Study. Arch Dis Childhood 2013; available online at http://fn.bmj.com/content/early/2012/01/20/archdischild-2011-300244.full.html

  • Marlow N, Pike K, Bower E, Brocklehurst P, Jones D, Kenyon S,  Kurinczuk JJ, Taylor D, Salt A.  Characteristics of children with cerebral palsy in the ORACLE Children Study. Developmental Medicine & Child Neurology 2012; 54:640-646.

  • Brugha TS, Matthews R, Morgan Z, Hill T, Alonso J, Jones DR. Methodology and reporting of systematic reviews and meta-analyses of observational studies in psychiatric epidemiology. A systematic review. Br J Psych 2012; 200: 446-453.

  • Sterne JAC, Sutton AJ, Ioannidis JPA, Terrin N, Jones DR et al. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials.  Br Med J 2011;343 d4002. Online at http://bmj.com/cgi/content/full/bmj.d4002
  • Dixon-Woods M, Tarrant C, Jackson CJ, Jones DR,  Kenyon S. Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach.  Clin Trials 2011;8(3):330-341.

  • Petticrew M, Chalabi  Z, Jones DR. To RCT or not to RCT: deciding when “more evidence is needed” for public health policy and practice.  J Epidem Comm Hlth 2012;66:391-396.

  • Bakali E, Pitchforth E, Tincello DG, Kenyon S, Slack M, Toozs-Hobson P, Mayne C, Jones DR, Taylor DJ.  Clinicians’ views on the feasibility of surgical randomized trials in urogynaecology: results of a questionnaire survey.  Neurourology and Urodynamics 2011;  30:69-74.
  • Jones DR, Pike K, Kenyon S, Pike L, Henderson B, Brocklehurst P, Marlow N, Salt A, Taylor DJ. Routine educational outcome measures in health studies: Key Stage 1 in the ORACLE Children Study follow-up of randomized trial cohorts. Arch Dis Childhood 2011; 96:25-29.     Supplementary materials are available (see above).  (For ORACLE Children Study data sharing policy, please click here)

  • Squire IS, Nelson C, Lambert PC, Jones DR, Ng L, Woods KL. Prognostic value of admission blood glucose concentration and diabetes diagnosis on survival after acute myocardial infarction; Results from 4702 index cases in routine practice.  Clinical Science 2010; 118: 527-535.

  • Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, Taylor DJ.  Has publication of the results of the ORACLE Children Study changed practice in the UK?  Br J Obs Gynae 2010; 117: 1344-9. (For ORACLE Children Study data sharing policy, please click here)

  • Goudie AC, Sutton AJ, Jones DR, Donald A. Empirical assessment suggests existing evidence could be used more fully in designing RCTs. J Clin Epidemiol 2010; 63: 983-91.
  • Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L, Moreno SG. Assessing publication bias in the presence of heterogeneity. J Roy Statist Soc A 2010; 173:575-591.

  • Hart A, Gosling JP, Boobis A, Coggon D, Craig P, Jones DR. Development of a framework for evaluation and expression of uncertainties in hazard and risk assessment. Research Report to Food Standards Agency, Project No. T01056. 2010 http://www.food.gov.uk/science/research/foodcomponentsresearch/riskassessment/t01programme/t01projlist/t01056/

  • Tincello DG, Kenyon SK, Slack M, Toozs-Hobson P, Mayne C, Jones DR, Taylor DJ. Colposuspension or TVT with anterior repair for urinary incontinence and prolapse: results of and lessons from a pilot randomised patient preference study (CARPET 1) .  Br J Obs Gynae 2009;116:1809-1814.

  • Sutton AJ, Cooper NJ, Jones DR. Evidence synthesis as the key to more coherent and efficient research. BMC Medical Research Methodology 2009, 9:29.

  • Jones DR, Peters JL, Rushton L, Sutton AJ, Abrams KR. Interspecies extrapolation in environmental exposure standard setting: a Bayesian synthesis approach. Regul Tox Pharm 2009; 53:217-225.  Available online at http://dx.doi.org/10.1016/j.yrtph.2009.01.011

  • Jones DR, Sutton AJ, Abrams K, Fenty J, Warren F, Rushton L. Systematic review and meta-analysis of mortality in crop protection product manufacturing workers. Occup Env Med 2009; 66:7-15.

  • Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, Taylor DJ. Childhood outcomes following prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7 year follow-up of the ORACLE I trial. Lancet 2008; 372:1310-18.  Available on line at http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61202-7/fulltext#article_upsell Supplementary tables are available. For ORACLE Children Study data sharing policy, please click here

  • Kenyon S, Pike K, Jones DR, Brocklehurst P, Marlow N, Salt A, Taylor DJ.  Childhood outcomes following prescription of antibiotics to pregnant women with spontaneous preterm labour: 7 year follow-up of the ORACLE II trial. Lancet 2008; 372: 1319-27.  Available on line at  http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61203-9/fulltext#article_upsell Supplementary tables are available. ORACLE Children Study data sharing policy, please click here

  • Nelson CP, Lambert PC, Squire I, Jones DR. Relative survival: what can cardiovascular disease learn from cancer? Eur Heart J 2008; 29: 941-947. See http://eurheartj.oxfordjournals.org/cgi/reprint/ehn079?
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  • Peters JL, Rushton L, Sutton AJ, Jones DR, Abrams KR.  The contribution of systematic review and meta-analysis methods to human health risk assessment: neurobehavioural effects of manganese. Journal of Human and Ecological Risk Assessment 2008; 14:1250-1272.

  • Jones DR, Sutton AJ, Peters JL. Meta-analysis in non-clinical risk assessment     In: Encyclopedia of Quantitative Risk Assessment. Melnick E, Everitt B (eds).  Wiley, Chichester, 2008; pp 1075-1084.

  • Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry. J Clin Epidemiol 2008; 61:991-996.  

  • Nelson CP, Lambert PC, Squire IS, Jones DR. Flexible Parametric Models for Relative Survival with Application in Coronary Heart Disease. Stat Med 2007; 26: 5486-5498.

  • Cooper NJ, Sutton AJ, Ades AE, Paisley S, Jones DR. on behalf of the working group on the use of evidence in economic decision models .   Use of evidence in economic decision models: practical issues and methodological challenges. Health Economics 2007;16:1277-1286.

  • Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L.  Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity. Stat Med 2007; 26: 4544-4562.   Supplementary materials available.

  • Sullivan E, Baker R, Jones DR, Blackledge H, Rashid A, Farooqi A, Allen J.  Primary healthcare teams' views on using mortality data to review clinical policies. Qual Saf Health Care 2007;16: 359-362.

  • Dixon-Woods M, Sutton AJ, Shaw RL, Miller T, Smith J, Young B, Bonas S, Booth A, Jones DR. Appraising qualitative research for inclusion in systematic reviews: a quantitative and qualitative comparison of three methods. Journal of Health Services Research and Policy 2007;12:42-47.

  • Sutton AJ, Cooper NJ, Jones DR, Lambert PC, Thompson JR, Abrams KR. Evidence-based sample size calculations based upon updated meta-analysis. Stat Med 2007;26:2479-2500.

  • Dixon-Woods M, Bonas S, Booth A, Jones DR, Millar T, Sutton AJ, Shaw RL, Smith JA, Young B. How can systematic reviews incorporate qualitative research? A critical perspective. Qual Res 2006;6:27-44.

  • Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Comparison of two methods to detect publication bias in meta-analysis. JAMA 2006; 295:676-680. Supplementary materials available.

  • Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. A systematic review of systematic reviews and meta-analyses of animal experiments with guidelines for reporting. J Environ Sci Health B 2006; B41(7) 1245-1258. Supplementary materials are available.

  • Alder N, Fenty J, Warren F, Sutton AJ, Jones DR, Abrams KR, Rushton L. Meta-analysis of mortality and cancer incidence among workers in the synthetic rubber producing industry. Am J Epidem 2006; 164: 405-420.

  • Boaz A, Ashby D, Denyer D, Egan M, Harden A, Jones DR, Pawson R, Tranfield D. A multitude of syntheses: a comparison of five approaches from diverse policy fields. Evidence and Policy 2006; 2:479-502.

  • An earlier paper (Moser, Fox and Jones: Unemployment and mortality in the OPCS longitudinal study. Lancet 1984;2:1324-29.) has been included in Richardson R (ed). Vintage papers from the Lancet. Edinburgh: Elsevier, 2006.

  • Dixon-Woods M, Bonas S, Booth A, Jones DR, Millar T, Sutton AJ, Shaw RL, Smith JA, Young B. How can systematic reviews incorporate qualitative research? A critical perspective. Qual Res 2006;6:27-44.

  • Peters JL, Jones DR, Rushton L, Sutton AJ, Abrams KR, Mugglestone MA. Bayesian methods for cross-design synthesis of epidemiological and toxicological evidence. J Roy Statist Soc C 2005;54:159-172. Supplementary materials are available.

  • Dixon-Woods M, Agarwal S, Jones DR, Young B, Sutton AJ.   Synthesising qualitative and quantitative evidence: a review of possible methods   J Health Serv Res Policy 2005; 10: 45-53.

  • Sutton AJ, Cooper NJ, Abrams KR, Lambert PC, Jones DR. A Bayesian approach to evaluating net clinical benefit allowed for parameter uncertainty. J Clin Epidem 2005; 58: 26-40.

  • Pritchard J, Cotterill SJ, Germond SM, Imeson J, de Kraker J, Jones DR. High dose Melphalan in the treatment of advanced neuroblastoma.: results of a randomised trial (ENSG-1) by the European Neuroblastoma Study group. Paed  Blood Cancer 2005; 44:348-357.

  • Lambert PC, Sutton AJ, Burton PR, Abrams KR, Jones DR.  How vague is vague? A simulation study of the impact of the use of vague prior distributions in MCMC using WinBUGS.  Stat Med 2005; 24:2401-2428.

  • Cooper NJ, Jones DR, Sutton AJ. The use of systematic reviews when designing studies. Clin Trials 2005; 2:260-264.

  • Lambert PC, Smith LK, Jones DR, Botha JL. Additive and multiplicative covariate regression models for relative survival incorporating fractional polynomials for time-dependent effects. Stat Med 2005; 24:3871-3886.

  • Kenyon S, Pike K, Jones DR , Taylor DJ, Salt A, Marlow N, Brocklehurst P. The effect of a monetary financial incentive on return of a postal health and development questionnaire: a randomised trial [ISRCTN 52995660]. BMC Health Services Research 2005; 5:55.  Copy available on Leicester Research Archive.

  • Dixon-Woods M, Agarwal S, Young B, Jones DR, Sutton AJ.  Integrative Approaches to Qualitative and Quantitative Evidence.  London: Health Development Agency, 2004.

  • Smith LK, Lambert PC, Botha JL, Jones DR.  Providing more up-to-date estimates of patient survival: a comparison of standard survival analysis with period analysis using life-table methods and proportional hazard models.  J Clin Epidem 2004;57:14-20.

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