Rhiannon K Owen

BSc(Hons) MSc PHD FHEA

Lecturer in Biostatistics
Biostatistics Research Group  Rhiannon Owen

CONTACT DETAILS

Department of Health Sciences
University of Leicester
George Davies Centre
University Road
Leicester LE1 7RH

Tel: 00 44 116 2297295

Email:   rhiannon.owen@le.ac.uk

Personal Details

  • Principal Investigator: NIHR Doctoral Research Fellowship: 2013-2017. “Evaluation of interventions for Overactive Bladder and Detrusor Overactivity: Development and application of evidence synthesis methods for extensive treatment networks” (DRF-2013-06-062).
  • Principal Investigator: NIHR Research Methods Fellowship: 2011-2013. “NIHR Methodology Programme” (MET-11-01-101).

Publications

Published:

  • Owen R.K., Bradbury N, Xin Y, Cooper N, Sutton A. MetaInsight: An interactive web‐based tool for analyzing, interrogating, and visualizing network meta‐analyses using R‐shiny and netmeta. Res Syn Meth. 2019; 1‐ 13. https://doi.org/10.1002/jrsm.1373
  • Owen R.K., Cooper N.J, Quinn T.J, Lees R., Sutton A.J. Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making. Journal of Clinical Epidemiology, 99, 64-74.
  • Owen R.K., Tincello D.G, Abrams K.R. 2015. Network meta-analysis: development of a 3-level hierarchical modelling approach incorporating dose-related constraints. Value in Health, 18: 116-126.
  • Owen, R.K., Abrams, K.R., Mayne, C., Slack, M. and Tincello, D.G., 2016. Patient factors associated with onabotulinum toxin A treatment outcome in women with detrusor overactivity. Neurourology and urodynamics, 36(2), 426-431.
  • Owen, R.K., Abrams, K.R., Mayne, C., Slack, M. and Tincello, D.G., 2016. Comparison of the effectiveness of repeated injections of onabotulinum toxin A for refractory idiopathic detrusor overactivity: analysis of an open label extension of a randomized trial (the RELAX study). Neurourology and Urodynamics, 36(4), 1201-1207.
  • Tincello D.G, Owen R.K., Slack M.C, Abrams K.R. 2012. Validation of the Patient Global Impression scales for use in detrusor overactivity: secondary analysis of the RELAX study. BJOG. 120(2): 212-216.

Under review:

  • Owen R.K., Abrams K.R, Jordan C.F, Bujkiewicz S.I, Tincello D.G. Comparative efficacy and safety of interventions for idiopathic detrusor overactivity and overactive bladder in adults: a systematic review and network meta-analysis. (Submitted to Annals of Internal Medicine)Rhiannon K Owen

Working papers:

  • Owen R.K., Sutton A.J. Bayesian evidence-based assurance calculations: Designing the next study.
  • Lensen, S., Owen R.K., Sutton A.J. Evidence-based sample size calculations: a case study in endometrial scratching.

Selected presentations:

  • MetaInsight: An interactive web-based tool for analyzing, interrogating and visualizing network meta-analyses. Cochrane Colloquium, Edinburgh, September 2018.
  • Network meta-analysis of diagnostic test accuracy studies allowing for multiple tests at multiple thresholds. International Society for Clinical Biostatistics, Australia, August 2018.
  • Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for health care policy and decision-making. Methods for Evaluation of medical prediction Models, Tests And Biomarkers (MEMTAB), Utrecht, July 2018.
  • MetaInsight: An interactive web-based tool for network meta-analyses. Methods in Meta-analysis, Imperial College London, December 2017.
  • Meta-analysis of diagnostic test accuracy studies for healthcare policy and decision making. Contributed workshop at the Global Evidence Summit (GES), Cape Town 2017.
  • Bivariate network meta-analysis of diagnostic test accuracy studies synthesizing multiple tests and multiple thresholds. Global evidence summit (GES), Cape Town, Sep 2017.
  • Meta-analysis of diagnostic test accuracy data as part of a workshop entitled Examples of collaborations with Cochrane Review Groups: Assessment of complex interventions, test accuracy and network meta-analyses. Cochrane UK annual meeting, Oxford, March 2017.
  • Comparative efficacy, safety and tolerability of interventions for idiopathic detrusor overactivity and overactive bladder syndrome: a systematic review and network meta-analysis. International Continence Society (ICS), Tokyo, Sep 2016.
  • Comparative efficacy, safety and tolerability of interventions for idiopathic detrusor overactivity and overactive bladder syndrome: a systematic review and network meta-analysis. (Awarded best oral presentation). United Kingdom Continence Society (UKCS), Belfast, April 2016.
  • Network meta-analysis for dose-response and class effects in decision making. Contributed workshop at the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), Milan, Nov 2015.
  • NIHR successful fellowship applications. Invited speaker at the NIHR Research Festival, Leicester, Feb 2015.
  • Network meta-analysis of interventions for overactive bladder and detrusor overactivity – a hierarchical modelling approach. Methods in Meta-analysis, RSS, London, July 2013.
  • Network meta-analysis of multiple outcomes: a simulated study and application. Methods in Meta-analysis, RSS London, December 2013.
  • Network meta-analysis and use of Bayesian methods for evaluating diminishing effects in overactive bladder syndrome. Invited seminar, Allergan UK, Marlow, 2013.

Research

  • Evidence synthesis methods for health technology assessment (including Network Meta-analysis and meta-analysis of diagnostic test accuracy data)
  • Bayesian statistical methods in healthcare evaluation
  • Evaluation of diagnostic test accuracy
  • Evidence-based research
  • Economic evaluation and analysis of value of information
  • Multimorbidity
  • Interactive web-based tools for analysing, interrogating and visualising complex statistical analyses

Teaching

Teaching interests include fundamental methods, epidemiology, clinical trials, evidence synthesis and decision modelling, for both statistical and non-statistical audiences. I have previously taught on the MSc in Medical Statistics including supervision of MSc dissertation projects, Bachelor of Medicine, Bachelor of Surgery undergraduate (MBChB) and MRes in Applied Health Research.

I have developed and delivered a number of short courses in collaboration with colleagues from the University of Bristol, including:

  • Evidence synthesis of diagnostic test accuracy for decision making: a 2-day WinBUGS course, NICE, London.
  • Systematic reviews and meta-analysis of diagnostic test accuracy, NICE, London.

Media

https://www.youtube.com/watch?v=euzcCngu-KQ&list=PLk9aEIq1hxPYCfyFem-eR089SJg9UbINd

https://www.youtube.com/watch?v=nIca0XQjBsA&index=3&list=PLk9aEIq1hxPYCfyFem-eR089SJg9UbINd

 

 

https://www.youtube.com/watch?v=chFMYXzkSGU&list=PLk9aEIq1hxPYCfyFem-eR089SJg9UbINd&index=2

 

 

Web-based tools

MetaInsight: An interactive web-based tool for analysing, interrogating and exploring network meta-analyses.

https://crsu.shinyapps.io/metainsightc/

https://crsu.shinyapps.io/metainsightb/

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