Next-generation sequencing approaches to short-tandem repeat sequence variation

This BBSRC-funded CASE studentship uses next-generation sequencing (NGS) to study the internal structure of human short-tandem repeats. These markers are universally used in forensic analysis, but genotyping considers only allele length, and not allele sequence. The next few years promise to bring the power of NGS to bear on forensic identification, yet little is known about what new opportunities and problems sequence data will bring. The project is co-supervised by Mark Jobling and Jon Wetton, is partnered by the company Key Forensic Services Ltd, and supports Tunde Huszar as a PhD student. We are also collaborating with Prof Sir Walter Bodmer, leader of the People of the British Isles project, and with Promega.

Selected publications

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