The laboratory has diversified away from Alzheimer’s disease, and now has interest in a range of medical conditions, with a focus on translational applications of genetics.

A central project is to find the genetic determinants of adverse reactions to radiotherapy in breast cancer. For this purpose we have recruited a large cohort of patients scored for toxicity and are carrying out genetic studies to find the genetic polymorphisms that influence risk. Genetic variants found will contribute to a future genetic test allowing oncologists to treat patients in a personalised fashion according to their genetic make-up.

We are extending this work into cervical and lung cancer, together with combined analyses of chemo- and radiotherapy.
Dr Paul Symonds is the clinical lead on the breast cancer project, Claire Esler on lung cancer.

Other projects include a collaboration with Indonesian researchers working on bone mineral density, with Irene Gottlob on nystagmus and Cristina Tufarelli on DNA methylation in radiation response.


Research Links

Search PubMed at the US National Library of Medicine for this author: Dr C. Talbot
Search Leicester Research ArchiveDr C. Talbot
Search Google ScholarDr C. Talbot




Share this page:

Contact Details

Department of Genetics
University of Leicester

Adrian Building
University Road
United Kingdom

Tel: +44 (0)116 252 3374
E Mail:

Head of Department
Professor Jacqui Shaw

Student complaints procedure


AccessAble logo

The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Adrian Building.