Publications

Human recombination hot spots hidden within regions of strong marker association.
Jeffreys AJ, Neumann R, Panayi M, Myers S & Donnelly P. Nature Genet. 37 601-606 (2005).

Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot.
Jeffreys AJ & Neumann R. Hum. Mol. Genet. 14 2277-2287 (2005).

Allelic recombination and de novo deletions in sperm in the human β-globin gene region.
Holloway K, Lawson VE & Jeffreys AJ. Hum. Mol. Genet. 15, 1099-1111 (2006).

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.
Neumann R. & Jeffreys AJ. Hum. Mol. Genet. 15 1401-1411 (2006).

Processes of de novo duplication of human α-globin genes.
Lam KWG & Jeffreys AJ. Proc. Natl. Acad. Sci. USA. 104 10950-10955 (2007).

Species-wide distribution of highly polymorphic minisatellite markers suggests past and present genetic exchanges among house mouse subspecies.
Bonhomme F, Rivals E, Orth A, Grant GR, Jeffreys AJ & Bois PR. Genome Biol. 8 R80 (2007).

Sperm crossover activity in regions of the human genome showing extreme breakdown of marker association.
Webb AJ, Berg IL, & Jeffreys AJ. Proc. Natl. Acad. Sci.USA. 105 10271-10632 (2008).

The rise and fall of a human recombination hot spot.
Jeffreys AJ & Neumann R. Nature Genet. 41 625-629 (2009).

Dynamics and processes of copy number instability in human γ-globin genes.
Neumann R, Lawson VE & Jeffreys AJ. Proc. Natl. Acad. Sci. USA, 107, 8304-8309 (2010).

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans.
Berg IL, Neumann R, Lam KWG, Sarbajna S, Odenthal-Hesse L, May CA & Jeffreys AJ.
Nature Genet. 42, 859-863 (2010).

 

 

Share this page:

Contact Details

Department of Genetics
University of Leicester

Adrian Building
University Road
Leicester
LE1 7RH
United Kingdom

Tel: +44 (0)116 252 3374
E Mail: genetics@le.ac.uk

Head of Department
Professor Jacqui Shaw

Student complaints procedure

Accessibility

AccessAble logo

The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Adrian Building.