Members of the LILR family of immunological receptors activate and inhibit innate immune responses. Although LILRB3 is predicted to be an inhibitory receptor based on intracellular domain sequence motifs, the lack of a known ligand means that its functions in the normal immune system and any role in disease are not clear.

Following a period of study leave with Prof John Trowsdale’s and Dr Des Jones in the Department of Pathology at the University of Cambridge, Colin continues to work on a project to characterise the identity of the ligand for LILRB3 and determine how its ligation affects macrophage function.

Research Links

Search PubMed at the US National Library of Medicine for this author: Dr C. Hewitt
Search Leicester Research ArchiveDr C. Hewitt
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