Lisa Emmens

Name

Email ID

le69@le.ac.uk

Qualifications

Research Area

Research Aim

Heart failure
Biomarker studies
Mass Spectrometry
Proteomics
Liquid chromatography

Investigating differences in biomarker profiles between responders and non-responders to therapy in heart failure

Overview

During the last decades, major improvements were made in the treatment of heart failure, leading to better outcomes. As a consequence, it becomes increasingly difficult to further improve outcome in these patients. However, mortality and morbidity in heart failure remain unacceptably high, so further improvements are required. Current research aims at identifying differences in biomarker profiles between responders and non-responders to currently recommended therapy in heart failure in order to identify patients with a poor prognosis. My current study is in proteomics, with the focus on discovering differences in lipoprotein profiles.
Previous research involved investigating the applicability of plasma KIM-1, a tubular damage marker, in daily cardiology practice as opposed to urinary KIM-1

Publications

Emmens JE, Ter Maaten JM, Matsue Y, Metra M, O'Connor CM, Ponikowski P, Teerlink JR, Cotter G, Davison B, Cleland JG, Givertz MM, Bloomfield DM, Dittrich HC, Todd J, van Veldhuisen DJ, Hillege HL, Damman K, van der Meer P, Voors AA. Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome. Eur J Heart Fail 2015; doi: 10.1002/ejhf.426. [Epub ahead of print]

Links

https://www.linkedin.com/in/lisa-emmens-30149663