Professor Toru Suzuki

Professor Toru SuzukiProfessor of Cardiovascular Medicine, Associate Dean, University of Leicester
Director, Leicester Life Sciences Accelerator
Honorary Consultant Cardiologist, University Hospitals of Leicester NHS Trust


Tel: +44 (0)116 204 4741


Address: Cardiovascular Research Centre, Glenfield Hospital, Leicester LE3 9QP.

Personal details



My research interests are centred on understanding the mechanistic basis of cardiovascular diseases with a special interest in translational aspects. Notably:

  • Gut microbiome and heart disease
  • Cardiovascular biomarkers/proteomics/phenomics  -- Leicester PI for the UK Consortium on MetAbolic Phenotyping (MAPUK)
  • Clinical/healthcare data science



Key publications

  • Israr MZ, Bernieh D, Salzano A, Cassambai S, Yazaki Y, Heaney LM, Jones DJ, Ng LL, Suzuki T. Association of gut-related metabolites with outcome in acute heart failure. Am Heart J. 2021;234:71-80.
  • Braverman AC, Mittauer E, Harris KM, Evangelista A, Pyeritz RE, Brinster D, Conklin L, Suzuki T, Fanola C, Ouzounian M, Chen E, Myrmel T, Bekeredjian R, Hutchison S, Coselli J, Gilon D, O'Gara P, Davis M, Isselbacher E, Eagle K. Clinical Features and Outcomes of Pregnancy-Related Acute Aortic Dissection. JAMA Cardiol. 2021;6:58-66.
  • Israr MZ, Salzano A, Yazaki Y, Voors AA, Ouwerkerk W, Anker SD, Cleland JG, Dickstein K, Metra M, Samani NJ, Ng LL, Suzuki T; BIOSTAT-CHF consortium.  Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT-CHF. Eur J Heart Fail. 2020;22:1486-1490.
  • Yazaki Y, Aizawa K, Israr MZ, Negishi K, Salzano A, Saitoh Y, Kimura N, Kono K, Heaney L, Cassambai S, Bernieh D, Lai F, Imai Y, Kario K, Nagai R, Ng LL, Suzuki T. Ethnic differences in association of outcomes with trimethylamine N-oxide in acute heart failure patients. ESC Heart Fail. 2020;7:2373-2378.
  • Salzano A, Israr MZ, Garcia DF, Middleton L, D’Assante R, Marra AM, Arcopinto M, Yazaki Y, Bernieh D, Cassambai S, Page K, Rengo G, Bossone E, Cittadini A, Shaw JA, Suzuki T.  Circulating cell-free DNA levels are associated with adverse outcomes in heart failure; testing liquid biopsy in heart failure.  Eur J Prev Cardiol. 2020:2047487320912375.
  • Salzano A, Israr MZ, Yazaki Y, Heaney LM, Kanagala P, Singh A, Arnold JR, Gulsin GS, Squire IB, McCann GP, Ng LL, Suzuki T. Combined use of trimethylamine N-oxide with BNP for risk stratification in heart failure with preserved ejection fraction: findings from the DIAMONDHFpEF study. Eur J Prev Cardiol. 2019:2047487319870355.
  • Yazaki Y, Salzano A, Nelson CP, Voors AA, Anker SD, Cleland JG, Lang CC, Metra M, Samani NJ, Ng LL, Suzuki T.  Geographical location affects the levels and association of trimethylamine N‐oxide with heart failure mortality in BIOSTAT‐CHF: a post-hoc analysis. Eur J Heart Fail. 2019 Jul 28. doi: 10.1002/ejhf.1550.
  • Cassambai S, Salzano A, Yazaki Y, Bernieh D, Wong M, Israr MZ, Heaney LM, Suzuki T.  Impact of acute choline loading on circulating trimethylamine N-oxide levels. Eur J Prev Cardiol. 2019 18:2047487319831372.
  • Suzuki T, Yazaki Y, Voors AA, Jones DJL, Chan DCS, Anker SD, Cleland JG, Dickstein K, Filippatos G, Hillege HL, Lang CC, Ponikowski P, Samani NJ, Van Veldhuisen DJ, Zannad F, Zwinderman AH, Metra M, Ng LL.  Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF).  Eur J Heart Fail. 2019;21:877-886.
  • Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators. Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research. Circulation. 2018;137:1846-60.
  • Israr MZ, Heaney LM, Ng LL, Suzuki T.  B-type Natriuretic Peptide Molecular Forms for Risk Stratification and Prediction of Outcome after Acute Myocardial Infarction.   Am Heart J. 2018;200 37-43.
  • Bossone E, Gorla R, LaBounty TM, Suzuki T, Gilon D, Strauss C, Ballotta A, Patel HJ, Evangelista A, Ehrlich MP, Hutchison S, Kline-Rogers E, Montgomery DG, Nienaber CA, Isselbacher EM, Eagle KA.  Presenting Systolic Blood Pressure and Outcomes in Patients With Acute Aortic Dissection.   J Am Coll Cardiol. 2018;71:1432-1440.
  • Suzuki T, Israr Z, Heaney LM, Takaoka M, Squire IB, Ng LL.  Prognostic role of molecular forms of B-type natriuretic peptide in acute heart failure.  Clin Chem. 2017;63:880-6.
  • Suzuki T, Heaney LM, Jones DJL, Ng LL.  T.  Trimethylamine N-oxide and risk stratification after acute myocardial infarction.  Clin Chem. 2017;63:420-428.
  • Nienaber C, Clough R, Sakalihasan N, Suzuki T, Gibbs R, Mussa F, Jenkins M, Thompson M, Evangelista A, Cheshire N, Rosendahl U, Pepper J.   Aortic dissection.   Nat Rev Dis Primers. 2016;2:16053.
  • Suzuki T, Lyon A, Saggar R, Heaney LM, Aizawa K, Cittadini A, Mauro C, Citro R, Limongelli G, Ferrara F, Vriz O, Morley-Smith A, Calabro P, Bossone E. Biomarkers of acute cardiovascular and pulmonary diseases. Eur Heart J Acute Cardiovasc Care. 2016;5:416-33.
  • Suzuki T, Heaney LM, Bhandari SS, Jones DJ, Ng LL.  Trimethylamine N-oxide and prognosis in acute heart failure. Heart. 2016;102:841-8
  • Sawaki D, Hou L, Tomida S, Sun J, Zhan H, Aizawa K, Son BK, Kariya T, Takimoto E, Otsu K, Conway SJ, Manabe I, Komuro I, Friedman SL, Nagai R, Suzuki T. Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes. Cardiovasc Res. 2015;107:420-430.
  • Son BK, Sawaki D, Tomida S, Fujita D, Aizawa K, Aoki H, Akishita M, Manabe I, Komuro I, Friedman SL, Nagai R, Suzuki T. Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma. Nat Commun. 2015 Apr 29;6:6994


View a full list of recent papers.

View a full list of book chapters.

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