Professor Rob Sayers

Professor Robert D Sayers

Professor of Vascular Surgery, University of Leicester

Department of Cardiovascular Sciences
University of Leicester
Robert Kilpatrick Clinical Sciences Building
Leicester Royal Infirmary
Leicester, LE2 7LX

Tel: +44 (0)116 252 3141

Email: rs152@le.ac.uk

Personal details

Honorary Vascular/Endovascular Surgeon, University Hospitals of Leicester NHS Trust

  • MB ChB (Hons), Birmingham 1984
  • FRCS (Ed), 1988
  • FRCS (Eng), 1989
  • MD, Leicester 1993

External positions

  • Member of the Court of Examiners, Royal College of Surgeons of England
  • Royal College of Surgeons Surgical Tutor, Leicester Royal Infirmary
  • Member of the Critical Care Steering Group, Royal College of Surgeons of England

Website

Publications

Rayt HS, Sandford RM, Salem M, Bown MJ, London NJ, Sayers RD. Conservative Management of Type 2 Endoleaks is not Associated with Increased Risk of Aneurysm Rupture. Eur J Vasc Endovasc Surg. 2009 Sep 18 Epub

Salem MK, Rayt HS, Hussey G, Rafelt S, Nelson CP, Sayers RD, Naylor AR, Nasim A. Should Asian Men be Included in Abdominal Aortic Aneurysm Screening Programmes? Eur J Vasc Endovasc Surg. 2009 Aug 8 Epub

Middleton RK, Bown MJ, Lloyd GM, Jones JL, London NJ, Sayers RD. Characterisation of Interleukin-8 and Monocyte Chemoattractant Protein-1 Expression within the Abdominal Aortic Aneurysm and their Association with Mural InflammationEur J Vasc Endovasc Surg. 2009 Jan 37 1 46-55

Rayt HS, Sutton AJ, London NJ, Sayers RD, Bown MJ. A Systematic Review and Meta-analysis of Endovascular Repair (EVAR) for Ruptured Abdominal Aortic AneurysmEur J Vasc Endovasc Surg. 2008 Nov 36 5 536-44

Aneurysm Consortium. Bown MJ, Child AH, Cockerill G, Deloukas P, Golledge J, Hafez H, Humphries SE, Jones GT, Norman PE, Powell JT, van Rij AM, Sayers RD, Samani NJ, Scott DJ, Thompson JR, Thompson MM. Genome Wide Association Studies: identifying the genes that determine the risk of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2008 Oct 36 4 395-6

Bown MJ, Lloyd GM, Sandford RM, Thompson JR, London NJ, Samani NJ, Sayers RD. The interleukin-10-1082 'A' allele and abdominal aortic aneurysmsJ Vasc Surg. 2007 Oct 46 4 687-93

Middleton RK, Lloyd GM, Bown MJ, Cooper NJ, London NJ, Sayers RD. The pro-inflammatory and chemotactic cytokine microenvironment of the abdominal aortic aneurysm wall: a protein array studyJ Vasc Surg. 2007 Mar 45 3 574-80

Norwood MG, Bown MJ, Sutton AJ, Nicholson ML, Sayers RD. Interleukin 6 production during abdominal aortic aneurysm repair arises from the gastrointestinal tract and not the legsBr J Surg. 2004 Sep 91 9 1153-6

Bown MJ, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. Cytokines, their genetic polymorphisms, and outcome after abdominal aortic aneurysm repairEur J Vasc Endovasc Surg. 2004 Sep 28 3 274-80

Papers before 2010

Brown CN, Sangal S, Stevens S, Sayers RD, Fishwick G, Nasim A. The EVAR Trial 1: has it led to a change in practice? Surgeon. 2009 Dec 7 6 326-31

Rayt HS, Sandford RM, Salem M, Bown MJ, London NJ, Sayers RD. Conservative Management of Type 2 Endoleaks is not Associated with Increased Risk of Aneurysm Rupture. Eur J Vasc Endovasc Surg. 2009 Sep 18 Epub

Salem MK, Rayt HS, Hussey G, Rafelt S, Nelson CP, Sayers RD, Naylor AR, Nasim A. Should Asian Men be Included in Abdominal Aortic Aneurysm Screening Programmes? Eur J Vasc Endovasc Surg. 2009 Aug 8 Epub

Sandford B, Bown M, London N, Sayers R. The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms. Int J Immunogenet. 2009 Aug 36 4 199-205

Middleton RK, Bown MJ, Lloyd GM, Jones JL, London NJ, Sayers RD. Characterisation of Interleukin-8 and Monocyte Chemoattractant Protein-1 Expression within the Abdominal Aortic Aneurysm and their Association with Mural Inflammation. Eur J Vasc Endovasc Surg. 2009 Jan 37 1 46-55

Rayt HS, Sutton AJ, London NJ, Sayers RD, Bown MJ. A Systematic Review and Meta-analysis of Endovascular Repair (EVAR) for Ruptured Abdominal Aortic Aneurysm. Eur J Vasc Endovasc Surg. 2008 Nov 36 5 536-44

Aneurysm Consortium. Bown MJ, Child AH, Cockerill G, Deloukas P, Golledge J, Hafez H, Humphries SE, Jones GT, Norman PE, Powell JT, van Rij AM, Sayers RD, Samani NJ, Scott DJ, Thompson JR, Thompson MM. Genome Wide Association Studies: identifying the genes that determine the risk of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2008 Oct 36 4 395-6

Sandford RM, Bown MJ, Sayers RD, Fishwick G, London NJ, Nasim A. Endovascular abdominal aortic aneurysm repair: 5-year follow-up results. Ann Vasc Surg. 2008 May-Jun 22 3 372-8

Rayt H, Lambert K, Bown M, Fishwick G, Morgan R, McCarthy M, London N, Sayers R. Can Surgeons Assess CT Suitability for Endovascular Repair (EVAR) in Ruptured Abdominal Aortic Aneurysm? Implications for a Ruptured EVAR Trial. Cardiovasc Intervent Radiol. 2008 Sep-Oct 31 5 865-9

Rayt HS, Bown MJ, Lambert KV, Fishwick NG, McCarthy MJ, London NJ, Sayers RD. Buttock Claudication and Erectile Dysfunction After Internal Iliac Artery Embolization in Patients Prior to Endovascular Aortic Aneurysm Repair. Cardiovasc Intervent Radiol. 2008 Jul-Aug 31 4 728-34

Franks S, Sutton A, Bown MJ, Sayers RD. Systematic review and meta-analysis of 12 years of endovascular abdominal aortic aneurysm repair. EJVES 2007;33:154-71.

Sandford R, Bown MJ, Sayers RD. Scoring systems do not accurately predict outcome following abdominal aortic aneurysm repair. A NZ J Surg 2007;77:275-82.

Norwood M, Lloyd G, Bown MJ, Fishwick G, London NJ, Sayers RD. Endovascular aneurysm repair. Postgraduate Med J 2007;83:21-7.

Karkos CD, McMahon GS, Markose G, Sayers RD, Naylor AR. Axillo-mesenteric bypass: An unusual solution to a difficult problem. J Vasc Surg 2007;45:404-7.

Sandford RM, Bown MJ, London NJ, Sayers RD. The genetic basis of abdominal aortic aneurysms: a review. Eur J Vasc Endovasc Surg 2007;33:381-90.

Middleton RK, Lloyd GM, Bown MJ, Cooper NJ, Sayers RD. The pro-inflammatory and chemotactic cytokine microenvironment of the AAA wall: A protein array study. J Vasc Surg 2007;45:574-80.

Karkos CD, McMahon G, McCarthy MJ, Dennis MJ, Sayers RD, London NJ, Naylor AR. The value of urgent carotid surgery for crescendo transient ischemic attacks. J Vasc Surg 2007;45:1148-54.

Sandford RM, Bown MJ, Sayers RD, London JN, Naylor AR, McCarthy MJ. Is infrainguinal bypass grafting successful following failed angioplasty? Eur J Vasc Endovasc Surg 2007;34:29-34.

Dunkley AJ, Stone M, Sayers R, Farooqi A, Khunti K. A cross sectional survey of secondary prevention measures in patients with peripheral arterial disease in primary care. Postgrad Med J 2007;83: 602-605.

Lloyd G, Bown MJ, Burton P, Thompson J, Samani NJ, Sayers RD. The interleukin-10 -1082 gene polymorphism and its relationship to pathogenesis and growth of abdominal aortic aneurysms. J Vasc Surg 2007;46:687-93.

Bown MJ, Fishwick G, Sayers RD, Bell PRF. Repair of ruptured abdominal aortic aneurysms by endovascular techniques. Adv Surg 2007;41:63-80.

Norwood MG, Sayers RD, Roscher S, Lynch NJ, Sutton AJ, Schwaeble WJ. Consumption of mannan-binding lectin during abdominal aortic aneurysm repair. Eur J Vasc Surg 2006;31:239-43.

Franks S, Lloyd G, Fishwick G, Bown M, Sayers RD. Endovascular treatment of ruptured and symptomatic abdominal aortic aneurysms. EJVES 2006;31:345-50.

Volodos S, Sayers RD, Bell PRF, Gostelow P. Impact of the volume of aneurysm contents on intra-aneurysm pressure after endovascular grafting. Angiol Sosud Khir 2006;11:64-71.

Sandford RM, Bown MJ, Fishwick G, Murphy F, Naylor M, Sensier Y, Sharpe R, Walker J, Hartshorn T, London NJ. Duplex ultrasound scanning is reliable in the detection of endoleak following endovascular aneurysm repair. European Journal of Vascular and Endovascular Surgery 2006; 32:5.

Norwood MG, Sayers RD, Roscher S, Lynch NJ, Sutton AJ. Consumption of mannan-binding lectin during abdominal aortic aneurysm repair. European Journal of Vascular and Endovascular Surgery 2006; 31:3.

Volodos SM, Sayers RD, Gostelow JP, Bell PRF. An investigation into the cause of distal endoleaks: Role of displacement force on the distal end of a stent-graft. Journal of Endovascular Therapy 2005; 12:1.

Bown MJ, Norwood MG, Sayers RD. The management of abdominal aortic aneurysms in patients with concurrent renal impairment. European Journal of Vascular & Endovascular Surgery 2005; 30:1-11.

Bown MJ, Weston S, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. A comparison of methods for determining genotypes at the tumour necrosis factor-alpha-308, interleukin (IL)-1beta+3953, IL-6 -174 and IL-10 -1082/-819/-592 polymorphic loci. International Journal of Immunogenetics 2005; 32:83-90.

Volodos SM, Sayers RD, Gostelow JP, Bell PR. An investigation into the cause of distal endoleaks: role of displacement force on the distal end of a stent-graft. Journal of Endovascular Therapy: Official Journal of the International Society of Endovascular Specialists 2005; 12:115-20.

Norwood MG, Horsburgh T, Bown MJ, Sayers RD. Neutrophil activation occurs in the lower-limbs of patients undergoing elective repair of abdominal aortic aneurysm. European Journal of Vascular & Endovascular Surgery 2005; 29:390-4.

Lazaris A, Sayers RD, Thompson M, Bell PR, Naylor AR. Patch corrugation on duplex ultrasonography may be an early warning of prosthetic patch infection. European Journal of Vascular & Endovascular Surgery 2005; 29:91-2.

Bown MJ, Norwood MG, Loftus IM, Spiers P, Sayers RD. The Surgical Acute Care Unit (SACU): effects on surgical workload and mortality. ANZ Journal of Surgery 2004; 74:881-4.

Bown MJ, Fishwick G, Sayers RD. The post-operative complications of endovascular aortic aneurysm repair. [Review] [116 refs] [Journal Article. Review. Review, Tutorial] Journal of Cardiovascular Surgery. 45(4):335-47, 2004 Aug.

Bown MJ, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. Cytokines, their genetic polymorphisms, and outcome after abdominal aortic aneurysm repair. European Journal of Vascular & Endovascular Surgery 2004; 28:274-80.

Norwood MG, Bown MJ, Sayers RD. Ischaemia-reperfusion injury and regional inflammatory responses in abdominal aortic aneurysm repair. European Journal of Vascular & Endovascular Surgery 2004; 28:234-45.

Lloyd GM, Newton JD, Norwood MG, Franks SC, Bown MJ, Sayers RD. Patients with abdominal aortic aneurysm: are we missing the opportunity for cardiovascular risk reduction? Journal of Vascular Surgery 2004; 40:691-7.

Norwood MG, Bown MJ, Sutton AJ, Nicholson ML, Sayers RD. Interleukin 6 production during abdominal aortic aneurysm repair arises from the gastrointestinal tract and not the legs. British Journal of Surgery 2004; 91:1153-6.

Norwood MG, Spiers P, Bailiss J, Sayers RD. Evaluation of the role of a specialist tracheostomy service. From critical care to outreach and beyond. Postgraduate Medical Journal 2004; 80(946):478-80.

Norwood MG, Bown MJ, Bell PR, Spiers P, Leslie A, Sayers RD. Evaluation of level 1 care facilities for vascular patients. ANZ Journal of Surgery 2004; 74:346-9.

Lloyd G, Bown M, Norwood M, Deb R, Fishwick G, Bell PRF, Sayers RD. The feasibility of pre-operative CT imaging in patients with ruptured aortic aneurysm: a time to death study in patients treated without operation. J Vasc Surg 2004;39:788-91

Norwood MGA, Lloyd G, Patel N, Panditi S, Moore S, Sayers RD. The changing face of femoral artery false aneurysms. EJVES 2004;27:385-8

Chorbadjian M, Bown M, Graham C, Sayers RD. Laparostomy healing by secondary intention after ruptured abdominal aortic aneurysm. Journal of Tissue Viability 2004;14:74-76

Norwood MGA, Bown MJ, Lloyd G, Bell PRF, Sayers RD. The clinical value of the systemic inflammatory response syndrome (SIRS) in abdominal aortic aneurysm repair. EJVES 2004;27:292-8

Norwood MGA, Polimenovi NM, Sutton AJ, Bown MJ, Sayers RD. Abdominal aortic aneurysm repair in patients with chronic renal disease. EJVES 2004;27:287-91

Bown MJ, Cooper NJ, Sutton AJ, Prytherch D, Nicholson ML, Bell PRF, Sayers RD. The post-operative mortality of ruptured abdominal aortic aneurysm repair. EJVES 2004;27:65-74

Volodos SM, Sayers RD, Gostelow JP, Bell PRF. Factors affecting the displacement force exerted on a stent graft after AAA repair-an in vitro study. EJVES 2003;26:596-601

Chorbadjian M, Bown M, Graham C, Sayers RD. Laparostomy healing by secondary intention after ruptured abdominal aortic aneurysm paper. Journal of Tissue Viability 2004;14:74-76

Shaw MBK, Cutress M, Papavassiliou V, White S, Thompson MM, Sayers RD. Duplicated inferior vena cava and crossed renal ectopia with abdominal aortic aneurysm. Pre-operative anatomic studies facilitate surgery. Clinical Anatomy 2003;16:355-7

Bown MJ, Burton PR, Horsburgh T, Nicholson ML, Bell PRF, Sayers RD. The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: a case control study. J Vasc Surg 2003;37:999-1005

Bown MJ, Horsburgh T, Nicholson ML, Bell PRF, Sayers RD. Cytokine gene polymorphisms and the inflammatory response to abdominal aortic aneurysm repair. Br J Surg 2003;90:1085-92

Bown MJ, Nicholson ML, Bell PRF, Sayers RD. The systemic inflammatory response syndrome (SIRS), organ failure and mortality after abdominal aortic aneurysm repair. J Vasc Surg 2003;37:600-6

Bown MJ, McCarthy M, Bell PRF, Sayers RD. Low atmospheric pressure is associated with rupture of abdominal aortic aneurysms. EJVES 2003;25:68-71

Bown MJ, Blanshard KS, Cutress ML, Sayers RD. Off-licence use of the Angio-Seal arterial puncture closure device. EJVES 2002;24:372-3

Cutress ML, Bown M, Warwick R, White S, Sayers RD. Spontaneous recanalisation of a ligated common carotid artery-a rare presentation of stroke. EJVES Extra 2002;4:20-1

Sayers RD. Aortic aneurysms, inflammatory pathways and nitric oxide (a Hunterian Lecture). Ann R Coll Surg Eng 2002;84:239-46

Murphy GJ, Sutton C, Kipgen D, Court F, Dennis MJ, Sayers RD. An aggressive policy of bilateral saphenous vein harvest for infragenicular revascularisation in the era of multi-drug resistant bacteria. Postgraduate Medical Journal 2002;78:339-43

Bown MJ, Sutton AJ, Bell PRF, Sayers RD. A meta-analysis of 50 years of ruptured abdominal aortic aneurysm repair. BJS 2002 89:714-730

Cutress ML, Blanshard K, Shaw M, Bown M, White S, Sayers RD. Endovascular repair of multiple peripheral aneurysms via a dual approach involving a venous conduit. EJVES 2002;23:365-6

Cutress ML, Blanshard K, Shaw M, Bown M, White S, Sayers RD. Retrograde subintimal angioplasty via a popliteal artery approach. EJVES 2002;23:275-6

Naylor A, Payne D, London N, Thompson MM, Dennis M, Sayers RD, Bell PRF. Prosthetic patch infection after carotid endarterectomy. EJVES 2002;23:11-16

Book chapters

Care of the Critically Ill Surgical Patient (2nd edition) faculty handbook. Anderson IA, Sayers RD (editors). 2003

Renal failure. Sayers RD. Care of the Critically Ill Surgical Patient (2nd edition). Arnold 2003

Acute compartment syndromes. Bown MJ, Sayers RD. Mechanisms of vascular disease: A textbook for vascular surgeons. Thompson MM, Fitridge R. Greenwich Medical Media 2003

Arterial aneurysms. Thompson MM, Sayers RD. Vascular and endovascular surgery 2nd edition. Beard JD, Gaines PA. WB Saunders Co Ltd 2000

Research

  • Pathogenesis and outcome of abdominal aortic aneurysms

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