Dr Bharat Sidhu

Cardiology Research Fellow, University of Leicester

 

MBChB 2010 University of Leicester

MRCP UK 2015 Royal College Physicians London

BSE Accreditation 2018, British Society of Echocardiography

 

Tel: 0116 258 3643

Email: bs283@le.ac.uk

Address: Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP

 

Research Interest

Atrial fibrillation (AF) is the most common type of chronic heart rhythm disease worldwide, with significant associated co-morbidities. Although there have been advances in understanding the mechanisms of AF, the underlying cause of AF and factors which perpetuate it remain poorly understood. This is particularly the case for persistent AF (persAF). Drug treatments for persAF have a role but can have undesirable side effects with relatively limited efficacy. Furthermore, current invasive therapies for persAF remain suboptimal, requiring significant resources, and with potentially serious complications for patients.

 

Catheter ablation is an effective treatment for paroxysmal AF. For persistent AF (persAF), however, catheter ablation does not provide similar results. This is because there remains a poor understanding of the electrophysiological mechanisms driving persAF.

 

My research aims to further explore the specific locations that represent important substrates which would guide more effective catheter ablation.

 

I will be using electromechanical mapping techniques in patients with persistent atrial fibrillation to identify targets for ablation in real time using an in-house graphical user interface (GUI) created by our own engineering team, and then go on to ablate these targets.

 

Our overall aim is to better understand the electrophysiological mechanisms underlying persistent AF so that we can have a guided approach to ablation in persistent AF.

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