Dr Amit Mistri

Brief profile for Dr Amit Mistri

Consultant in Stroke Medicine, University Hospitals of Leicester NHS Trust
Honorary Senior Lecturer - Cardiovascular Sciences

Email: amit.mistri@uhl-tr.nhs.uk

Acute Stroke Unit, Level 3, Windsor Building, Leicester Royal Infirmary LE1 5WW

Personal Details

  • Consultant Physician in Stroke Medicine - University Hospitals of Leicester NHS Trust - Aug 2008 to date
  • Deputy Clinical Director, Emergency & Specialty Medicine, UHL NHS Trust - Aug 2018 to date


Chair - UHL Anti-Coagulation Committee - Sep 2016 to Aug 2020
Clinical Senate,
UHL NHS Trust - Member April 2016 to Mar 2017; Vice Chair Mar 2017 to Aug 2018
Coordinator - East Midlands Stroke Group - Nov 2010 to Nov 2017
Governance Advisor for Electronic Prescribing, UHL NHS Trust - Aug 2014 to Aug 2018
Lead for Clinical Research - Stroke Medicine, UHL NHS Trust - Aug 2010 to Aug 2018
Lead for Clinical Audit - Stroke Medicine, UHL NHS Trust - Jan 2011 to Mar 2017
Lead for Clinical Governance - Stroke Medicine, UHL NHS Trust - Jan 2011 to Mar 2015
Clinical Lead – Trent Stroke Research Network (South) - August 2010 to April 2014
Lead for VLE Pilot (UHL Education Improvement Group) - Sept 2013 to Feb 2014


  • MB BS Christian Medical College, Vellore, India, 1995
  • MRCP (UK) Royal College of Physicians, London 2001
  • MD University of Leicester, Leicester 2009
  • FRCP (UK) Royal College of Physicians, London 2018



  • Special Senses Block - Secondary Prevention of Stroke
  • MSc Diabetes - Stroke and Diabetes Interface
  • CMT Teaching - Critical Appraisal of Research
  • Simulation teaching: Stroke & TIA scenarios


  • Vascular Biology Module - Physiological Control of BP; Blood Pressure Variability; Clinical Trial Interpretation
  • People and Diseases course - Clinical Teaching
  • Consultation Skills Foundation Course - Clinical Teaching
  • Nervous System Module - Blood Supply to the Brain & Spinal Cord
  • MSc Lectures: Biochemistry - Cerebrovascular Disease; Pain Module - Post-stroke Pain


Law ZK, Dineen R, Cala L, England TJ, Mistri AK, Appleton JP, Ozturk, S, Bereczki D, Ciccone A, Bath PM, Sprigg N, on behalf of the TICH-2 investigators. Predictors and outcomes of neurological deterioration in intracerebral haemorrhage: results form the TICH-2 trial.
Translational Stroke Research 2020 in press

Minhas J, Coles B, Mistri AK, Eveson D, Hussain ST, Potter JF, Khunti K, Robinson TG. What is the optimal blood pressure for patients with atrial fibrillation treated with direct oral anticoagulants?
Journal of Hypertension 2020 online publication ahead of print

Highton P, Mistri A, Seidu S. The East Midlands Atrial Fibrillation ADVANCE Program: A service evaluation
Australian Journal of General Practice 2020 submitted

Mankoo AS, Minhas JS, Coles B, Hussain ST,,Khunti K, Robinson TG, Mistri AK, Eveson DJ;  on behalf of the LeiSTAR Steering Committee. Clinical relevance of orthostatic hypotension  in patients with atrial fibrillation and suspected transient ischaemic attack.
High Blood Pressure and Cardiovascular Prevention 2020; 27 (1): 93-101 (alternative pdf link)

Minhas JS, Rook W, Panerai RB, Hoiland RL, Ainslie PN, Thompson JP, Mistri AK, Robinson TG. Pathophysiological and clinical considerations in the perioperative care of patients with a previous ischaemic stroke: a multidisciplinary narrative review
British Journal of Anaesthesia 2020; 124(2): 183-196 (alternative pdf link)

Law ZK, England TJ, Mistri AK, Woodhouse LJ, Cala L, Dineen R, Ozturk S, Beridze M, Collins R, Bath PM, Sprigg, N; on behalf of TICH-2 investigators. Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid. 
European Stroke Journal 2020; 0(0): 1-7 https://doi.org/10.1177/2396987320901391

Bhat Y, Dixit A, Mistri A, Patel B, Quoraishi SH, Uprichard J. A mixed methodology, non-interventional study to evaluate the use of direct oral anticoagulants in UK clinical practice for patients with a first stroke associated with non-valvular atrial fibrillation: study protocol.
BMC Neurology 2019; 19 (306)

Bridgwood  B, Lager  KE, Mistri  AK, Khunti  K, Wilson  AD, Modi  P. Interventions for improving modifiable risk factor control in the secondary prevention of stroke.
Cochrane Database of Systematic Reviews 2018, Issue 5. Art. No.: CD009103.  DOI: 10.1002/14651858.CD009103.pub3.
Stroke. 2018;49:e301-e302. DOI: 10.1161/STROKEAHA.118.022213

Bose P, Tarrant C, Mistri A, Wilson A. Managing uncertainty: A qualitative study of GPs’ views on the diagnosis and immediate management of Transient Ischaemic Attack and the potential of a diagnostic tool.
Family Practice 2018; 35(6): 738-743

Hawkins L, Lincoln NB, Sprigg N, Ward NS, Mistri A, Tyrell P, Worthington E, & Drummond A.  The Nottingham Fatigue After Stroke (NotFAST) Study: Results from follow-up six months after stroke.
Topics in Stroke Rehabilitation 2017 DOI: 10.1080/10749357.2017.1368912

Bose P, Wilson A, Mistri AK. The Diagnosis and Management of Transient Ischemic Attack (TIA) in Primary Care:A Systematic Review.
The Journal of Primary Health Care 2017; 9 (2): 114-130

Hawkins L, Lincoln NB, Sprigg N, Ward N, Mistri A, Tyrell P, Worthington E, Drummond A. The Nottingham Fatigue After Stroke (NotFAST) study: Factors associated with severity of fatigue in stroke patients without depression. 
Clinical Rehabilitation 2017; 1-10 (DOI 10.1177/0269215517695857)

Katbamna S,  Manning L, Mistri A, Johnson S, Robinson TG. Balancing Satisfaction and Stress: Carer Burden among White and British Asian Indian carers of stroke survivors. 
Ethnicity & Health 2017; 22: 425-41.

Minhas JS; Syed NF; Haunton VJ; Panerai RB; Robinson TG; Mistri AK. Is dynamic cerebral autoregulation measurement using transcranial Doppler ultrasound reproducible in the presence of high concentration oxygen and carbon dioxide? 
Physiol. Meas. 2016; 37: 673-82. doi:10.1088/0967-3334/37/5/673

Manning LS, Mistri AK, Rothwell PM, Potter JF, Robinson TG. Prognostic significance of blood pressure variability in acute stroke: observational analysis of the CHHIPS and COSSACS trials. 
Stroke 2015; 46: 1518-1524.

Manning L, Katbamna S, Johnson M, Mistri A, Robinson T.  British Indian carers of stroke survivors experience higher levels of anxiety and depression than White British carers: findings of a prospective observational study.
Diversity and Equality in Health and Care 2014; 11 (3-4): 187-200.

Lager KE, Wilson AD, Mistri AK, Khunti K.  Stroke services for risk reduction in the secondary prevention of stroke.
Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD009103.
DOI: 10.1002/14651858.CD009103.pub2.

Lager K, Wilson A, Khunti K, Mistri AK. Secondary prevention measures in TIA patients: a cross-sectional study.
Postgraduate Medical Journal 2012; 88: 305-311. doi:10.1136/postgradmedj-2011-130484

Banahan C, Patel R, Jeyagopal V, Mistri A, Hague JP, Evans DH, Chung EML. Microbubble signal properties from PFO tests using transcranial Doppler ultrasound.
Perspectives in Medicine 2012, 1: 232-235 .

Huq R, Philbey CE, Mistri AK, Panerai RB, Robinson, TG. Dynamic cerebral autoregulation assessed by respiratory manoeuvres in non-insulin-treated Type 2 diabetes mellitus.
Diabetic Medicine 2012; 29(5): 609-613

Saeed NP, Horsfield MA, Panerai RP, Mistri AK, Robinson TG.  Measurement of cerebral blood flow responses to the thigh cuff maneuver: a comparison of TCD with a novel MRI method.
Journal of Cerebral Blood Flow and Metabolism 2011, 31 (5): 1302-1310

Robinson TG, Potter JF, Ford GA, Bulpitt CJ, Chernova J, Jagger C, James MA, Knight J, Markus HS, Mistri AK, Poulter NR; COSSACS Investigators. Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial. 
Lancet Neurology 2010 Aug 9 8 767-75

Wilson EC, Ford GA, Robinson T, Mistri A, Jagger C, Potter JF. Controlling hypertension immediately post stroke: a cost utility analysis of a pilot randomised controlled trial. 
Cost Effectiveness and Resource Allocation 2010 Mar; 23 (8):  3


Designated Medical Practitioner for Non-Medical Prescribing Course - Poonam Varu 2017-18; Habibab Hafeji 2018-19; Barry Fogarty 2018-19
PhD - Priyanka Bose - 2015 - 2020; Kate Lager PhD - 2010-13
MD - Lisa Manning 2013-16; Victoria Haunton - 2010-13
BSc - Ravinthu Thilakawardhana & Shamilah Rahman - 2013-14; Peter Connell - 2012-13; Nazia Syed & Sara Al-Ansari - 2011-12

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