Professor Timothy J Coats

Professor Tim Coats

Personal details

  • Professor of Emergency Medicine
  • +44 (0)116 258 6965
  • @tjcoats


For general enquiries, please email Elizabeth Cadman on (secretary) or telephone +44 (0)116 258 5965.


Tim Coats trained in Emergency Medicine in Leeds and London, developing a particular interest in pre-hospital trauma care, and completing an MD thesis on the incorporation of patterns of change in physiology in a predictive model of outcome following injury.

Following appointed as a Senior Lecturer in London in 1996 with the London HEMS service, he moved to the University of Leicester as Professor of Emergency Medicine in 2004. He is a past Chair of the College of Emergency Medicine Research Committee, past Chair of the NIHR National Specialist Group for Injuries and Emergencies, and Chairs the Trauma Audit and Research Network (TARN). His current research interests ( are changes in coagulation following injury (in particular the role of antifibrinolytics following injury), non-invasive monitoring in the diagnosis of sepsis in emergency care ( and quality improvement based on predictive outcome modelling.



  • BSc (Psychology) 1983, University of London
  • MB BS, 1986, University of London
  • FRCS (Eng), 1990
  • FFAEM 1996
  • MD, 1997, University of London


Selected Publications

Reed MJ, Grubb NR, Lang CC, et al. Multi-centre Randomised Controlled Trial of a Smartphone-based Event Recorder Alongside Standard Care Versus Standard Care for Patients Presenting to the Emergency Department with Palpitations and Pre-syncope: The IPED (Investigation of Palpitations in the ED) study. EClinicalMedicine 2019;8:37-46. doi:

Desborough M, Salman R-S, Stanworth S, et al. Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): rationale and design of a phase II double blind randomised controlled trial. 2019

Davies F, Coats TJ. ‘Stealth trauma’in the young and the old: the next challenge for major trauma networks? Emergency medicine journal 2019:emermed-2019-208694.

Coats TJ, Fragoso-Iñiguez M, Roberts I. Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study. Emerg Med J 2019;36(2):78-81.

Brenner A, Afolabi A, Ahmad SM, et al. Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Trials 2019;20(1):467.

Clinical evaluation of a prototype 'brain tv' (tissue velocimetry) ultrasound system for emergency assessment of suspected acquired brain injury. Journal of Cerebral Blood Flow and Metabolism; 2019. Sage Publications Inc 2455 Teller Rd, Thousand Oaks, Ca 91320 USA.

Implementation of tranexamic acid for bleeding trauma patients: a longitudinal and cross-sectional study. Coats TJ, Fragoso-Iñiguez M, Roberts I. Emerg Med J. 2019 Feb;36(2):78-81. doi: 10.1136/emermed-2018-207693. Epub 2018 Dec 8.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, and Rowan KM, for the ProMISe Trial Investigators. (2015). Trial of early, goal-directed resuscitation for septic shockN Engl J Med, 372(14), 1301-1311.

Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MP, Ahern A, Griggs K, Scott R, Hinds C, Rowan K; OPTIMISE Study Group. Inc Coats TJ. (2014) Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic reviewJAMA. June 4;311(21):2181-90

Goodacre S, Cohen J, Bradburn M, Gray A, Benger J, Coats T; 3Mg Research Team. Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial.Lancet Respir Med. 2013 Jun;1(4):293-300

Roberts I, Perel P, Prieto-Merino D, Shakur H, Coats T, Hunt BJ, Lecky F, Brohi K, Willett K; CRASH-2 Collaborators. Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trialBMJ. 2012 Sep 11;345:e5839

CRASH-2 collaborators, Roberts I, Shakur H, Afolabi A, Brohi K, Coats T, Dewan Y, Gando S, Guyatt G, Hunt BJ, Morales C, Perel P, Prieto-Merino D, Woolley T. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trialLancet. 2011 Mar 26 377 9771 1096-101

Roberts I, Shakur H, Ker K, Coats T; CRASH-2 Trial collaborators. Antifibrinolytic drugs for acute traumatic injuryCochrane Database Syst Rev. 2011 Jan 19 1

Goodacre SW, Bradburn M, Cross E, Collinson P, Gray A, Hall AS; RATPAC Research Team. The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency departmentHeart. 2011 Feb 97 3 190-6

CRASH-2 trial collaborators, Shakur H, Roberts R, Bautista R, Caballero J, Coats T, Dewan Y, El-Sayed H, Gogichaishvili T, Gupta S, Herrera J, Hunt B, Iribhogbe P, Izurieta M, Khamis H, Komolafe E, Marrero MA, Mejía-Mantilla J, Miranda J, Morales C, Olaomi O, Olldashi F, Perel P, Peto R, Ramana PV, Ravi RR, Yutthakasemsunt S.
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010 Jul 3;376(9734):23-32. Epub 2010 Jun 14

Shakur H, Roberts I, Barnetson L, Coats T. Clinical trials in emergency situationsBMJ. 2007 Jan 27 334 7586 165-6

Brohi K, Singh J, Heron M, Coats T. Acute traumatic coagulopathyJ Trauma. 2003 Jun 54 6 1127-30

Becalick DC, Coats TJ. Comparison of artificial intelligence techniques with UKTRISS for estimating probability of survival after trauma. UK Trauma and Injury Severity ScoreJ Trauma. 2001 Jul 51 1 123-33

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