Dr Gerrit Woltmann MD, FRCP (London)

Honorary Senior Lecturer

Contact details

Department of Respiratory Medicine, Glenfield Hospital

Telephone: (+44) (0)116 223 1415

E-mail: gerrit.woltmann@uhl-tr.nhs.uk or gw20@le.ac.uk

Research

Dr Woltmann is a consultant respiratory physician at Glenfield Hospital and clinical TB Lead. The Leicester TB services have over the past 10 years achieved a sustained reduction of TB incidence in the region despite opposite national trends. He has a strong scientific interest in the prevention of tuberculosis through rapid access to services and through systematic screening for latent TB infection (LTBI) of risk groups and preventative treatment strategies. He has a strong interest in clinical database development and deep clinical phenotyping of chronic disease. He is the IT Lead of the Respiratory BRU.

Specific interests include:

  • Determinants of TB progression from LTBI
  • Cost effective screening strategies for LTBI
  • Safe preventative treatment for LTBI
  • Effective prevention of LTBI
  • Specialty led / database based electronic medical records including TB database development and airway disease database development (ADD platform)

He also has an interest in upper and lower airway diseases including sputum analysis using laser scanning cytometry.

Selected Recent Publications

  1. Panchal RK, Browne I, Monk P, Woltmann G, Haldar P. The effectiveness of
    primary care based risk stratification for targeted latent tuberculosis infection
    screening in recent immigrants to the UK: a retrospective cohort study. Thorax. 2014 Apr;69(4):354-62. doi: 10.1136/thoraxjnl-2013-203805. Epub 2013 Nov 19. PubMed PMID: 24253833.
  2. Bakali E, Brown L, Woltmann G, Tincello DG. Solitary vaginal sarcoidosis
    without other manifestations of systemic disease. J Obstet Gynaecol. 2012
    Nov;32(8):814-6. doi: 10.3109/01443615.2012.710665. PubMed PMID: 23075368.
  3. Haldar P, Thuraisingam H, Patel H, Pereira N, Free RC, Entwisle J, Wiselka M, Hoskyns EW, Monk P, Barer MR, Woltmann G. Single-step QuantiFERON screening of adult contacts: a prospective cohort study of tuberculosis risk. Thorax. 2013 Mar;68(3):240-6. doi: 10.1136/thoraxjnl-2011-200956. Epub 2012 Sep 6. PubMed PMID: 22956558.
  4. Bothamley GH, Kruijshaar ME, Kunst H, Woltmann G, Cotton M, Saralaya D, Woodhead MA, Watson JP, Chapman AL. Tuberculosis in UK cities: workload and effectiveness of tuberculosis control programmes. BMC Public Health. 2011 Nov 28;11:896. doi: 10.1186/1471-2458-11-896. PubMed PMID: 22122757; PubMed Central PMCID: PMC3235177.
  5. Thomas B, Pugalenthi A, Patel H, Woltmann G, Bankart J, Hoskyns W. Concordance between tuberculin skin test and interferon-γ assay and interferon-γ response to mitogen in pediatric tuberculosis contacts. Pediatr Pulmonol. 2011 Dec;46(12):1225-32. doi: 10.1002/ppul.21494. Epub 2011 Jun 16. PubMed PMID: 21681979.
  6. Karia S, Woltmann G, Raj V. Old cavity, new cancer - is it time to re-think?
    JRSM Short Rep. 2011 Mar 21;2(3):18. doi: 10.1258/shorts.2011.010135. PubMed PMID: 21541086; PubMed Central PMCID: PMC3086330.
  7. Pareek M, Watson JP, Ormerod LP, Kon OM, Woltmann G, White PJ, Abubakar I, Lalvani A. Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis. Lancet Infect Dis. 2011 Jun;11(6):435-44. doi: 10.1016/S1473-3099(11)70069-X. Epub 2011 Apr 20. PubMed PMID: 21514236; PubMed Central PMCID: PMC3108102.
  8. Cheah ES, Malkin J, Free RC, Lee SM, Perera N, Woltmann G, Patel H, Kimmitt PT, Smith RJ, Rajakumar K, Barer MR. A two-tube combined TaqMan/SYBR Green assay to identify mycobacteria and detect single global lineage-defining polymorphisms in Mycobacterium tuberculosis. J Mol Diagn. 2010 Mar;12(2):250-6. doi:10.2353/jmoldx.2010.090030. Epub 2010 Jan 21. PubMed PMID: 20093392; PubMed Central PMCID: PMC2871733.
  9. Mukamolova GV, Turapov O, Malkin J, Woltmann G, Barer MR.
    Resuscitation-promoting factors reveal an occult population of tubercle Bacilli
    in Sputum. Am J Respir Crit Care Med. 2010 Jan 15;181(2):174-80. doi:
    10.1164/rccm.200905-0661OC. Epub 2009 Oct 29. PubMed PMID: 19875686; PubMed Central PMCID: PMC2809243.
  10. Rew DA, Woltmann G, Kaur D. Near-clinical applications of laser scanning
    cytometry. Methods Mol Biol. 2006;319:193-212. PubMed PMID: 16719356.
  11. Bunn HJ, Woltmann G, Grigg J. Applicability of laser scanning cytometry to
    study paediatric alveolar macrophages. Eur Respir J. 2002 Dec;20(6):1437-43. PubMed PMID: 12503701.
  12. Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID.
    Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax. 2002 Oct;57(10):875-9. PubMed PMID: 12324674; PubMed Central PMCID: PMC1746199.
  13. Wardlaw AJ, Brightling CE, Green R, Woltmann G, Bradding P, Pavord ID. New insights into the relationship between airway inflammation and asthma. Clin Sci (Lond). 2002 Aug;103(2):201-11. Review. PubMed PMID: 12149112.
  14. Hunter CJ, Brightling CE, Woltmann G, Wardlaw AJ, Pavord ID. A comparison of the validity of different diagnostic tests in adults with asthma. Chest. 2002 pr;121(4):1051-7. PubMed PMID: 11948032.
  15. Wardlaw AJ, Brightling C, Green R, Woltmann G, Pavord I. Eosinophils in
    asthma and other allergic diseases. Br Med Bull. 2000;56(4):985-1003. Review. PubMed PMID: 11359633.
  16. Brightling CE, Ward R, Woltmann G, Bradding P, Sheller JR, Dworski R, Pavord ID. Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma. Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 1):878-82. PubMed PMID: 10988099.
  17. Woltmann G, McNulty CA, Dewson G, Symon FA, Wardlaw AJ. Interleukin-13 induces PSGL-1/P-selectin-dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow. Blood. 2000 May 15;95(10):3146-52. PubMed PMID: 10807781.
  18. Brightling CE, Woltmann G, Wardlaw AJ, Pavord ID. Development of irreversible airflow obstruction in a patient with eosinophilic bronchitis without asthma. Eur Respir J. 1999 Nov;14(5):1228-30. PubMed PMID: 10596716.
  19. Pavord ID, Ward R, Woltmann G, Wardlaw AJ, Sheller JR, Dworski R. Induced sputum eicosanoid concentrations in asthma. Am J Respir Crit Care Med. 1999 Dec;160(6):1905-9. PubMed PMID: 10588604.
  20. Hunter CJ, Ward R, Woltmann G, Wardlaw AJ, Pavord ID. The safety and success rate of sputum induction using a low output ultrasonic nebuliser. Respir Med.1999 May;93(5):345-8. PubMed PMID: 10464902.
  21. Pavord ID, Brightling CE, Woltmann G, Wardlaw AJ. Non-eosinophilic
    corticosteroid unresponsive asthma. Lancet. 1999 Jun 26;353(9171):2213-4. PubMed PMID: 10392993.
  22. Woltmann G, Ward RJ, Symon FA, Rew DA, Pavord ID, Wardlaw AJ. Objective quantitative analysis of eosinophils and bronchial epithelial cells in induced sputum by laser scanning cytometry. Thorax. 1999 Feb;54(2):124-30. PubMed PMID: 10325916; PubMed Central PMCID: PMC1745427.
  23. Ward R, Woltmann G, Wardlaw AJ, Pavord ID. Between-observer repeatability of sputum differential cell counts. Influence of cell viability and squamous cell contamination. Clin Exp Allergy. 1999 Feb;29(2):248-52. PubMed PMID: 10051730.
  24. Rew DA, Woltmann G, Wardlaw AJ. Laser-scanning cytometry. Lancet. 1999 Jan 23;353(9149):255-6. PubMed PMID: 9929014.
  25. Woltmann G, Wardlaw AJ, Rew DA. Image analysis enhancement of the laser scanning cytometer. Cytometry. 1998 Nov 1;33(3):362-5. PubMed PMID: 9822348.

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Contact Details

College of Life Sciences
University of Leicester
Maurice Shock Building
University Road
Leicester
LE1 7RH