Dr Clare Gillies, PhD, MSc (International HTA), MSc (Medical Statistics), BSc

Lecturer in Medical Statistics

Diabetes Research Centre
University of Leicester
Leicester General Hospital
Gwendolen Road
Leicester, LE5 4PW

Tel: +44 (0)116 258 8916

Email: clg13@le.ac.uk

 

Research Interests

  • Evidence synthesis
  • Decision models
  • Real World Evidence
  • Diabetes
  • Multimorbidity

 

Professional Activities

Regional advisory committee member for Research for Patient Benefit (East Midlands)

 

Postgraduate Supervision and Training

Elpida Vounzoulaki September 2018 -
University of Leicester, jointly with Professor Khunti, Dr Clare Gillies and Francesco Zaccardi, Diabetes Research Centre 
Type 2 diabetes in women after a diagnosis of gestational diabetes: Understanding uptake to screening, progression rates and costs

Yogini Chudasama January 2017 –
University of Leicester, jointly with Professor Khunti, Dr Clare Gillies and Francesco Zaccardi, Diabetes Research Centre
Epidemiology and health care costs of multimorbidity in the UK

Usman Muhammad September 2016 –
University of Leicester, jointly with Professor Khunti and Dr Clare Gillies, Diabetes Research Centre
Effectiveness of intensive interventions compared to standard care in individuals with type 2 diabetes mellitus and microalbuminuria

Zoe Morgan (part-time) April 2016-
University of Leicester, jointly with Professor Terry Brugha and Dr Clare Gillies
The association between attention deficit hyperactivity disorder (ADHD) with autism spectrum disorder (ASD) and other psychiatric conditions, in the adult general population.


Selected Publicatons

43. Levene LS, Coles BD, Gillies CL, Shabnam S, Zaccardi F, Khunti K. Predictors of hypertension detection in English general practices : a cross sectional  study. J Public Health (Oxf) 2021 Jan 13. Doi: 10.1093/pubmed/fdaa224. [Online ahead of print] .PMID: 33434926

42. Rowlands AV, Kloecker DE, Chudasama Y, Davies MJ, Dawkins NP, Edwardson CL, Gillies C, Khunti K, Razieh C, Islam N, Zaccardi F, Yates T. Association of Timing and Balance of Physical Activity and Rest/Sleep with risk of COVID-19: A UK Biobank study. Mayo clinical Proceedings 2021 Jan .96(1):156-164.Doi: 10.1016/j.mayocp.2020.10.032. [Epub 2020 Oct 31]. PMID:33413813

41. Seidu S, Gillies C, Farooqi A, Trivedi H, Brady E, Davies MJ, Khunti K. A cost comparison of an enhanced primary care diabetes service and standard care. Primary care Diabetes 2020 Dec. Doi: 10.1016/j.pcd.2020.10.011. [Online ahead of print]. PMID: 33279438

40.Patel V, Gillies C, Patel P, Davies T, Hansdot S, Lee V, Lakhani M, Khunti K, Gupta P. Reducing vitamin D requests in a primary care cohort: a quality improvement study. BJGP Open 2020 Nov 3. Doi: 10.3399/bjgpopen20X101090. [Online ahead of print].PMID: 33144362

39. Chudasama YV, Gillies CL, Zaccardi F, Coles B, Davies MJ, Seidu S, Khunti K. Impact of COVID-19 on routine care for chronic diseases : A global survey of views from healthcare professionals. Diabetes and Metabolic Syndrome 2020 Sep-Oct.14 (5): 965-967. DOI: 10.1016/j.dsx.2020.06.042.[Epub 2020 June 23]. PMID: 32604016

38. Seidu S, Gillies C, Zaccardi F, Kunutsor SK,Hartmann-Boyce J, Yates T, Singh AK, Davies MJ,  Khunti K. The impact of obesity on severe disease and mortality in people with SARS-CoV-2: A systematic review and meta-analysis. Endocrinology, Diabetes and metabolism 2020 Aug. DOI: 10.1002/edm2.176. [Online ahead of print]. PMID: 32904932

37. Gillies C; Alexander Research Committee, Farmer A, Maximova K, Willows ND. Alexander First Nations Parents' Perceptions of a School Nutrition Policy. Can J Diet Pract Res. 2020 Jun 1;81(2):66-71. Doi: 10.3148/cjdpr-2019-026. [Epub 2019 Sep 12].PMID: 31512509

36. Vounzoulaki E, Khunti K, Abner SC, Tan BK, Davies MJ, Gillies CL. Progression to  type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis. BMJ 2020 May.13; 369:m1361. DOI: 10.1136/bmj.m1361. PMID: 32404325

35. Adan M, Gillies C, Tyrer F, Khunti K.The multimorbidity epidemic: challenges for real world research. Primary Health Care Research and Development 2020 Mar 6; 21: e6. DOI: 10.1017/S146342361900094X. PMID: 32138803

34 Sathanapally H, Sidhu M, Fahami R, Gillies C, Kadam U, Davies MJ, Khunti K, Seidu S. Priorities of patients with multimorbidity and of clinicians regarding treatment and health outcomes: a systematic mixed studies review. BMJ Open 2020 Feb.10 (2):e033445. DOI: 10.1136/bmjopen-2019-033445. PMID: 32051314

33. Chudasama YV, Zaccardi F, Gillies CL, Dhalwani NN, Yates T, Rowlands AV, Davies MJ, Khunti K. Leisure-time physical activity and life expectancy in people with cardiometabolic multimorbidity and depression. Journal of Internal Medicine 2020 Jan. 287(1):87-99.DOI: 10.1111/joim.12987. [Epub 2019 Nov 6]. PMID: 31602698

32.Yogini V. Chudasama, Kamlesh K. Khunti, Francesco Zaccardi, Alex V. Rowlands, Thomas Yates, Clare L. Gillies, Melanie J. Davies and Nafeesa N. Dhalwani. Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study BMC Medicine 2019 17:108

31. Clague-Baker N, Robinson T, Hagenberg A, Drewry S, Gillies C, Singh S. Physiotherapy. The validity and reliability of the Incremental Shuttle Walk Test and Six-minute Walk Test compared to an Incremental Cycle Test for people who have had a mild-to-moderate stroke. 2019 Jun;105(2):275-282. doi: 10.1016/j.physio.2018.12.005.

30. Gillies CL, Farrukh A, Abrams KR, Mayberry JF. Risk of esophageal cancer in achalasia cardia: A meta‐analysis. Journal of gastroenterology and hepatology. 2019 Feb.  doi.org/10.1002/jgh3.12132

29. Kar D, Gillies C, Nath M, Khunti K, Davies MJ, Seidu S. Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis. Acta Diabetologica. 2019 Feb; 1-12. doi.org/10.1007/s00592-019-01293-x

28. Usman M, Gillies CL, Khunti K, Davies MJ. Effects of intensive interventions compared to standard care in people with type 2 diabetes and microalbuminuria on risk factors control and cardiovascular outcomes: A systematic review and meta-analysis of randomised controlled trials. Diabetes Res Clin Pract. 2018 Dec; 146:76-84. doi: 10.1016/j.diabres.2018.10.002

27. Dallosso H, Yates T, Mani H, Gray LJ, Dhalwani N, Baldry E, Gillies C, Cradock S, Batt M, Davies MJ, Khunti K. Movement through Active Personalised engagement (MAP) - a self-management programme designed to promote physical activity in people with multimorbidity: study protocol for a randomised controlled trial. Trials. 2018 Oct 20; 19(1) :576. doi: 10.1186/s13063-018-2939-2

26. Jadawji C, Crasto W, Gillies C, Kar D, Davies MJ, Khunti K, Seidu S. Prevalence and progression of diabetic nephropathy in South Asian, white European and African Caribbean people with type 2 diabetes: A systematic review and meta-analysis. Diabetes Obes Metab. 2018 Nov 8. doi: 10.1111/dom.13569

25. Seewoodharry MD, Maconachie GDE, Gillies CL, Gottlob I, McLean RJ. The effects of feedback on adherence to medication and treatment: A systematic review and meta-analysis of randomised controlled trials. Am J Prev Med. 2017 Apr 26. pii: S0749-3797(17)30182-4. PMID: 28456347

24. Kar D, Gillies CL, Zaccardi F, Webb D, Seidu S, Tesfaye S, Davies MJ, Khunti K. Relationship of cardiometabolic parameters in non-smokers, current smokers, and quitters in diabetes: a systematic review and meta-analysis. Cardiovasc Diabetol. 2016 Nov 24;15(1):158. PMID: 27881170

23. Khunti K, Gillies CL, Dallosso H, Brady EM, Gray LJ, Kilgallen G, Willis A, Zafar A., Davies MJ. Assessment of response rates and yields for Two opportunistic Tools for Early detection of Non-diabetic hyperglycaemia and Diabetes (ATTEND). A randomised controlled trial and cost-effectiveness analysis. Diabetes Res Clin Pract. 2016 Aug; 118:12-20. PMID: 27485852

22.Gillies CL, Freemantle N, Grieve R, Sekhon J, Forder J. Advancing quantitative methods for the evaluation of complex interventions. In Raine R, Fitzpatrick R, Barratt H, Bevan G, Black N, Boaden R, et al. Challenges, solutions and future directions in the evaluation of service innovations in health care and public health. Health Serv Deliv Res2016;4(16):37–54. doi: 10.3310/hsdr04160-37

21. Fouweather T, Gillies CL, Wohland P, Van Oyen H, Nusselder W, Robine JM, Cambois E, Jagger C; JA: EHLEIS Team. Comparison of socio-economic indicators explaining inequalities in Healthy Life Years at age 50 in Europe: 2005 and 2010. Eur J Public Health. 2015 Dec; 25(6):978-83. PMID: 25876883

20. Baker R, Camosso-Stefinovic J, Gillies CL, Shaw EJ, Cheater F, Flottorp S, Robertson N, Wensing M, Fiander M, Eccles MP, Godycki-Cwirko M, van Lieshout J, Jäger C. Tailored interventions to address determinants of practice. Cochrane Database Syst Rev. 2015 Apr 29; 4: CD005470. PMID: 25923419

19. Evans RA, Kaplovitch E, Beauchamp MK, Dolmage TE, Goldstein RS, Gillies CL, Brooks D, Mathur S. Is quadriceps endurance reduced in COPD? A systematic review. Chest. 2015 Mar; 147 (3):673-84. doi: 10.1378/chest.14-1079. PMID: 25340989

18. Ashra NB, Spong R, Carter P, Davies MJ, Dunkley A, Gillies CL, Greaves C, Khunti K, Sutton S, Yates T, Youssef D, Gray LJ. Systematic review and meta-analysis assessing the effectiveness of pragmatic lifestyle interventions for the prevention of type 2 diabetes mellitus in routine practice. Public Health England, 2015.

17. Wohland P, Rees P, Gillies CL, Alvanides S, Matthews FE, O'Neill V, Jagger C. Drivers of inequality in disability-free expectancy at birth and age 85 across space and time in Great Britain. Journal of Epidemiology & Community Health. 2014 Sep; 68(9): 826-833. PMID: 24907279

16. Khunti K, Gillies CL, Taub NA, Mostafa SA, Hiles SL, Abrams KR, Davies MJ. A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: Modelling study. Diabetes Res Clin Pract. 2012; 97(3):505-13. PMID: 22554999

15. Jones R, Freeman C, Johnson M, Stevens J, Woods HB, Guillaume L, Gillies CL, Goyder E, Chilcott J, Payne N. Preventing the progression of pre-diabetes to type 2 diabetes in adults. Systematic review and meta-analysis of lifestyle, pharmacological and surgical interventions. Report commissioned by NICE and produced by ScHARR (2012).

14.Jagger C, Gillies CL, Cambois E, Van Oyen H, Nusselder WJ, Robine J. Trends in disability-free life expectancy at age 16 and age 65 in the European union 1995-2001: a comparison of 13 EU countries. Gerontologist. 2011; 51:250-250 01.

13. Jagger C, Gillies CL, Robine J. Similarities and differences in health expectancies across the lifecourse in Europe. Gerontologist. 2010; 50:196-196 01.

12. Jagger C, Gillies CL, Cambois E, Van OH, Nusselder, W, Robine J, the EHLEIS team. The Global Activity Limitation Index measured function and disability similarly across European countries. Journal of Clinical Epidemiology. 2010 Aug; 63(8):892-899. PMID: 20171842

11. Baker R, Camosso Stefinovic J, Gillies CL, Shaw EJ, Cheater F, Flottorp S, Robertson N. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database of Systematic Reviews. 2010 Mar 17;(3):CD005470. PMID: 20238340

10. Jagger C, Gillies CL, Moscone F, Cambois E, Van Oyen H, Nusselder W, Robine J and the EHLEIS team. Inequalities in healthy life years in the 25 countries of the European Union in 2005: a cross-national meta-regression analysis. The Lancet. 2008; 372(9656): 2124-2131. PMID: 19010526

9. Gillies CL, Lambert PC, Abrams KR, Sutton AJ, Cooper NJ, Hsu R, Davies MJ, Khunti K. A cost-effectiveness analysis for different strategies for the screening and prevention of type 2 diabetes mellitus. British Medical Journal. 2008, 336: 1180-1185. doi: https://doi.org/10.1136/bmj.39545.585289.25

8 Cheater FM, Baker R, Gillies CL, Wailoo A, Spiers N, Reddish S, Robertson N, Cawood C. The nature and impact of urinary incontinence experienced by patients receiving community nursing services: A cross-sectional cohort study. International Journal of Nursing Studies. 2008; 45(3): 339-351. PMID: 17178120

7. Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu R, Khunti K. Pharmacological and Lifestyle Interventions to Prevent or Delay Type 2 Diabetes Mellitus in Individuals with Impaired Glucose Tolerance: A Systematic Review and Meta-analysis. British Medical Journal. 2007; 334(7588):299. PMID: 17237299

6. Williams KS, Assassa RP, Gillies CL, Abrams KR, Turner DA, Shaw C, Haslam J, Mayne C, McGrother CW, and the Leicestershire MRC Incontinence Study Team. A randomised controlled trial of the effectiveness of pelvic floor therapies for urodynamic stress and mixed incontinence. BJU International. 2006; 98(5): 1043-1050. PMID: 17034605

5. Cheater FM, Baker R, Reddish S, Spiers N, Wailoo A, Gillies CL, Robertson N, Cawood C. Cluster Randomised Controlled Trial Of The Effectiveness Of Audit And Feedback And Educational Outreach On Improving Nursing Practice And Patient Outcomes. Medical Care. 2006; 44(6): 542-51. PMID: 16708003

4. Middleton JF, Mckinley RB, Gillies CL. A randomised controlled trial of patient completed agenda forms and physician education about the patient’s agenda on the outcome of general practice consultations. British Medical Journal. 2006; 332: 1238-1242.

3. Abrams KR, Gillies CL, Lambert PC. Meta-Analysis of Heterogeneously Reported Trials Assessing Change from Baseline. Statistics in Medicine. 2005; 24(24): 3823-3844. PMID: 16320285

2. Baker R, Sanderson-Mann J, Longworth S, Cox R, Gillies CL. Randomised controlled trial to compare general practitioner run orthopaedic clinics based in hospital outpatient departments and general practices. British Journal of General Practice. 2005; 55(521): 912-917. PMID: 16378559

1. Shaw B, Cheater F, Baker R, Gillies CL, Hearnshaw H, Flottorp S, Robertson N. Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. The Cochrane Database of Systematic Reviews. 2005; (3):CD005470. PMID: 16034980

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