Dr Charlotte Edwardson, Bsc, MSc,PhD

Associate Professor in Physical Activity, Sedentary Behaviour and Health


Diabetes Research Centre

University of Leicester

Leicester General Hospital

Gwendolen road, Leicester, LE5 4PW

Email: ce95@le.ac.uk

Tel : 0116 258 8577

Personal Details

Charlotte completed a BSc in Applied Sports Science (2004) and MSc (2005) and PhD (part time, 2010) in Physical Activity and Health, all from Loughborough University. Alongside her PhD she worked as a Research Associate (2005-2010) for the Institute of Youth Sport, Loughborough University where she specialised in the evaluation of physical activity and health initiatives in young people. Following this she moved into the area of diabetes prevention and worked as a Research Associate, University Hospitals of Leicester (2010-2013), on several large randomised controlled trials focused on increasing physical activity and reducing sedentary behaviour in people with a high risk of type 2 diabetes.

In 2013 she was appointed Lecturer, and subsequently Associate Professor in early 2016, in Physical Activity, Sedentary Behaviour and Health in the Diabetes Research Centre, University of Leicester. Her research focuses on understanding the role of physical activity and sedentary behaviour in the prevention and management of chronic diseases, particularly type 2 diabetes. This encompasses experimental, epidemiological and behaviour change intervention studies. She has published over 115 research articles and currently holds research grants (totalling ~£9 million) from prestigious funding bodies such as the Medical Research Council, National Institute for Health Research, Department of Health and the European Commission.


Research Interest

  • The patterning and profiling of physical activity and sedentary behaviour in different populations
  • The relationship between characteristics of physical activity and sedentary behaviour and health
  • Interventions to increase physical activity and reduce sedentary behaviour
  • Objectively measuring and processing physical activity and sedentary behaviour (activPAL, ActiGraph, GENEActiv)

Current Research Projects

  • Stand Out in Class: Restructuring the classroom environment to reduce sedentary behaviour - a pilot cluster randomised controlled trial (funded by the NIHR PHR)
  • Development of open source software to process activPAL data
  • A three arm cluster randomised controlled trial to test the effectiveness and cost-effectiveness of the SMART Work & Life programme for reducing daily sitting time in office workers (funded by the NIHR PHR)
  • SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation – The SEESAW Study (funded by Boehringer Ingelheim)
  • Promoting lifestyle change and self-management through structured education in people with multi-morbidity: A randomised controlled trial(funded by CLAHRC East Midlands)
  • Chronotype of Patients with Type 2 Diabetes and Effect on Glycaemic Control: The CODEC study (funded by the NIHR BRC)
  • A cluster randomised controlled trial to investigate the effectiveness and cost-effectiveness of a Structured Health Intervention For Truckers (The SHIFT Study) (funded by the NIHR PHR)
  • The effects of reducing prolonged sitting bouts with regular light upright movement breaks on glucose regulation in individuals at high risk of or with type 2 diabetes (funded by the NIHR BRC)


Peer reviewer for international journals and conference societies including:

  1. PLoS One
  2. International Journal for Behavioural Nutrition and Physical Activity
  3. Preventive Medicine
  4. Medicine and Science in Sports and Exercise
  5. Journal of Physical Activity & Health
  6. BMC Public Health
  7. Journal of Science and Medicine in Sport
  8. International Society for Behavioural Nutrition and Physical Activity
  9. Associate Editor for BMC public Health and Frontiers in Sports and Active Learning
  10. Guest Editor for International Congress of Ambulatory Monitoring and Physical Activity Measurement  2015 : Focus issue in Physiological Measurement
  11. Grant Reviewer for NIHR Public Health Research programme




Phil McBride, October 2019 to September 2022
University of Leicester, jointly with Dr Tom Yates , Diabetes Research Centre. Sedentary Behaviour and physical function

Publications(MOST RECENT)

For full list of publications please visit : https://scholar.google.com/citations?user=9kEB7rcAAAAJ&hl=en

1. Deirdre M Harrington, Emer M Brady, Susann Weihrauch-Blüher, Charlotte L Edwardson, Laura J Gray, Michelle Hadjiconstantinou, Janet Jarvis, Kamlesh Khunti, Itziar Vergara, Irati Erregerena, Rogerio T Ribeiro, Jacqui Troughton, Andriani Vazeou and Melanie J Davies. Development of an interactive lifestyle programme for adolescents at risk of developing type 2 diabetes: PRE-STARt. Children. 20218(2), 69.

2. Lorraine Harper, Catherine A Hewitt, Ian Litchfield, Matthew D Morgan, Dimitrios Chanouzas, Hollie K Caulfield, Linda Coughlan, Caroline Dean, Kate Fletcher, Fiona Cramp, Sheila Greenfield, Natalie J Ives, Sue Jowett, Shalela Kodabuckus, Sarah Tearne, Sukhwant Sehmi, Charlotte Edwardson, Nathan Dawkins, Amanda Daley. Management of fatigue with physical activity and behavioural change support in vasculitis: an open label randomised controlled feasibility study. Rheumatology. 2020 Dec 28;keaa890.

3. Plekhanova T, Edwardson CL, Rowlands AV, Davies MJ, Hall A, Khunti K, Yates T. Associations between accelerometer determined physical activity and sleep behaviours in obese men. Medicine and Science in Sports and Exercise. In press.

4. Argyridou S, Bernieh D, Henson J, Edwardson CL, Davies MJ, Khunti K, Suzuki T, Yates T. Associations between physical activity and Trimethylamine N-oxide (TMAO) in those at risk of Type 2 Diabetes. BMJ Open Diabetes Research and Care 2020;8:e001359.

5. Rowlands A, David E Kloecker, Yogini Chudasama, Melanie J Davies, Nathan P Dawkins, Charlotte L Edwardson, Clare Gillies, Kamlesh Khunti, Cameron Razieh, Nazrul Islam, Francesco Zaccardi, Tom Yates. Association of timing and balance of activity and sleep/rest and risk of COVID-19 in UK Biobank. Mayo Clinic Procedings. 2021 Jan; 96(1): 156–164.

6. Abigail S. Morris, Rebecca C. Murphy, Nicola D. Hopkins, Paula M. Watson, David Low, Genevieve N. Healy, Charlotte L. Edwardson, Brendan Collins, Hannah Timpson, Sam O. Shepherd, Madeleine Cochrane, David Gavin, Lee E. F. Graves. Sit Less and Move More - A multi-component intervention with and without height-adjustable workstations in contact centre call agents: a pilot randomised trial. Journal of Occupational and Environmental Medicine. 2021 Jan 1;63(1):44-56.

7. Sargeant JA, Jelleyman C, Coull NA, Edwardson CL, Henson J, King JA, Khunti K, McCarthy M, Rowlands AV, Stensel DJ, Waller HL, Webb DR, Davies MJ, Yates T. Improvements in glycaemic control after acute moderate-intensity continuous or high-intensity interval exercise are greater in South Asians than white Europeans with nondiabetic hyperglycaemia: a randomised crossover study. Diabetes Care. 2021 Jan;44(1):201-209.

8. Ulf Ekelund, Jakob Tarp, Morten W Fagerland, Jostein Steene-Johannessen, Bjørge H Hansen, Barbara J. Jefferis, Peter Whincup, Keith M Diaz, Steven P Hooker, Virginia J Howard, Ariel Chernofsky, Martin G Larson, Nicole L Spartano, Vasan S Ramachandran, Ing-Mari Dohrn, Maria Hagströmer, Charlotte L Edwardson, Thomas Yates, Eric J Shiroma, Paddy C Dempsey, Katrien Wijndaele, Sigmund A Anderssen, I-Min Lee. Joint associations of accelerometer measured physical activity and sedentary time with all-cause mortality: A harmonized meta-analysis in more than 44,000 middle-aged and older individuals. BJSM. 2020 Dec;54(24):1499-1506.

9. Rowlands AV, Davies MJ, Dempsey PC, Edwardson CL, Razieh C, Yates T. Wrist-worn accelerometers: what is the minimum clinically important difference (MCID) in daily average acceleration for inactive adults? BJSM. 2020 Sep 14;bjsports-2020-102293.

10.  Dawkins NP ,Yates T, Edwardson CL, Maylor B, Davies MJ, Dunstan D, Highton PJ, Herring LY, Khunti K, Rowlands AV. Comparing 24h physical activity profiles :office workers, women with a history of gestational diabetes and people with chronic disease condition(s). Journal of Sports Sciences. 2021 Jan.39 (2):219-226.

11.Mickute M, Henson J, Rowlands AV, Sargeant JA, Webb D, Hall AP, Edwardson CL, Baldry E, Brady EM, Khunti K, Davies MJ, Yates T. Device-measured physical activity and its association with physical function in adults with type 2 diabetes mellitus. Diabetic Medicine. 2020 Aug 26. DOI: 10.1111/dme.14393. [Online ahead of print].PMID: 32844472

12. Sean P Cumming, Deirdre M Harrington, Melanie J Davis, Charlotte L Edwardson, Trish Gorely, Kamlesh Khunti, Alex V Rowlands, Thomas Yates & Lauren B SherarMaturational timing, physical self-perceptions and physical activity in UK adolescent females: investigation of a mediated effects model, Annals of Human Biology. 2020 47:4, 384-390.

13.Plekhanova T, Rowlands AV, Yates T, Hall A, Brady E, Davies M, Khunti K, Edwardson CL. Equivalency of sleep estimates from three research-grade accelerometers worn on the non-dominant and dominant wrist with and without use of a sleep log. Journal of the Measurement of Physical Behaviours. 2020, 3, 294-303.

14.Henson J, Rowlands A, Baldry A, Brady E, Davies M, Edwardson C, Yates T, Andrew Hall. Physical behaviour and chronotype in people with type 2 diabetes. BMJ Open Diabetes Research and Care. 2020; 8(1): e001375.

15.Clemes SA, Bingham DD, Pearson N, Chen Y, Edwardson CL, McEachan RRC, Tolfrey K, Cale L, Richardson G, Fray M, Altunkaya J, Bandelow S, Bhupendra Jaicim N, Salmon J, Dunstan DW, Barber SE. Stand Out in Class: Restructuring the classroom environment to reduce sitting time – findings from a pilot cluster randomised controlled trial. IJBNPA. 2020 Apr 29;17(1):55.

16.Rowlands AV, Edwardson CL, Dawkins NP, Maylor BD, Metcalf KM, Janz KF. Physical activity for bone health: How much and/or how hard? Medicine and Science in Sports and Exercise. 2020 Nov;52(11):2331-2341.

17. Biddle SJH, O’Connell S, Davies M, Dunstan D, Edwardson CL, Esliger DW, Gray LJ, T, Munir F. Reducing sitting at work: process evaluation of the SMArT Work (Stand More AT Work) cluster randomised controlled trial. Trials. 2020 May 13;21(1):403.

18.Munir F*, Miller P, Biddle SJH, O’Connell S, Davies M, Dunstan D, Esliger DW, Gray LJ, Yates T, Edwardson CL*. Cost-benefit analysis of the SMArT Work (Stand More AT Work) intervention to reduce sitting time. The International Journal of Environmental Research and Public Health. 2020 Feb 13;17(4):1214. * Joint first author

19. Henson J, Edwardson CL, Gill J, Zaccardi F, Khunti K, Davies M, Yates T. Physical activity and lipidomics in a population at high risk of type 2 diabetes. Journal of Sports Sciences. 2020 May;38(10):1150-1160.

20. Henson J, Edwardson CL, Davies MJ, Khunti K, King J, Stensel D, Zaccardi F, Yates T. Predictors of the acute post-prandial response to breaking up prolonged sitting. Medicine and Science in Sports and Exercise. 2020 Jun;52(6):1385-1393.

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