Professor Pratik Choudhary, FRCP, MD, MRCP, MBBS

Professor/ Honorary Consultant in Diabetes.

CONTACT DETAILS

Diabetes Research Centre

Leicester Diabetes Centre

University of Leicester

Leicester General Hospital

Leicester, LE5 4PW

Tel: +44 116 258 4874

Email: pratik.choudhary@leicester.ac.uk

 

Biography

Professor Pratik Choudhary is Professor of Diabetes at the University of Leicester, having joined there recently after 15 years at King’s College London. He has clinical and research interests into the mechanisms and management of hypoglycemia unawareness and the use of education and technology, especially new insulin pumps and continuous glucose monitors in the management of diabetes. He is work-package lead for the Hypo-RESOLVE consortium within that is PI of a large multinational study evaluating the biological and psychosocial impacts of sensor detected hypoglycaemia.

He is chair of the Diabetes Technology Network – UK, Medical Advisor to the Department of Transport, associate editor for Diabetic Medicine and member of the EASD Post Graduate education committee.

Professor Pratik Choudhary had different leadership roles.

  • DTN-UK – Committee member (2016 )
  • Associate Editor -Diabetic Medicine (2015 )
  • Member: Novo Nordisk UK Research Foundation Committee ( 2018)
  • Organising Committee: Annual Diabetes Technology Meeting - Bethesda (2016 )
  • Co-developed #Languagematters project for India T1eUp

Research Interests

  • Epidemiology and management of hypoglycaemia
  • Technology in diabetes - Continuous glucose monitoring and insulin pump therapy
  • Intensive insulin therapy, Education and Psychology in type 1 diabetes
  • Mechanisms and management of hypoglycaemia unawareness
  • Islet cell transplantation

Publications

2021

56. Byrne J, Willis A, Dunkley A, Fitzpatrick C, Campbell S, Sidhu MS, Choudhary P, Davies MJ, Khunti K. Individual, healthcare professional and system-level barriers and facilitators to initiation and adherence to injectable therapies for type 2 diabetes: A systematic review and meta-ethnography. Diabet Med 2021 Aug 25:e14678. Doi:10.1111/dme.14678. [Online ahead of print]. PMID: 34432914

55.  Choudhary P, Bellido V, Graner M, Altpeter B, Cicchetti A, Durand-Zaleski I, Kristensen FB. The Challenge of Sustainable Access to Telemonitoring Tools for People with Diabetes in Europe : Lessons from COVID-19 and Beyond. Diabetes Ther 2021 Sep;12(9):2311-2327. doi: 10.1007/s13300-021-01132-9. [Epub 2021 Aug 14].PMID: 34390477

54.  Mahmoudi Z, Del Favero S, Jacob P, Choudhary P; Hypo-RESOLVE Consortium. Toward an Optimal Definition of Hypoglycemia with Continuous Glucose Monitoring. Comput Methods Programs Biomed 2021 Jul 27;209:106303. doi: 10.1016/j.cmpb.2021.106303.[ Online ahead of print]. PMID: 34380077

53. Danne T, Limbert C, Puig Domingo M, Del Prato S, Renard E, Choudhary P, Seibold A. Telemonitoring, Telemedicine and Time in Range during the Pandemic: Paradigm Change for Diabetes Risk Management in the Post-COVID Future. Diabetes Ther 2021 Sep;12(9):2289-2310. doi: 10.1007/s13300-021-01114-x.[ Epub 2021 Aug 2].PMID: 34338994

52. Camerlingo N, Vettoretti M, Sparacino G, Facchinetti A, Mader J, Choudhary P, Del Favero S, Hypo-RESOLVE Consortium.  Design of clinical trials to assess diabetes treatments: minimal duration of CGM data to estimate time-in-ranges with a desired precision. Diabetes Obes Metab. 2021 Jul 1. Doi: 10.1111/dom.14483. Online ahead of print. PMID: 34212483

51. Roversi C, Vettoretti M, Del Favero S, Facchinetti A, Choudhary P, Sparacino G.  Impact of Carbohydrate Counting Error on Glycemic Control in Open-Loop Management of Type 1 Diabetes: Quantitative Assessment Through an in silico Trial. J Diabetes Sci Technol. 2021 May 12;19322968211012392. Doi: 10.1177/19322968211012392. Online ahead of print. PMID: 33978501

50.Patel D, Dashora U, Reeve R, Choudhary P, Robbins T.  ABCD, DTN-UK, and YDEF News. British Journal of Diabetes, Vol 21, No 1 (2021), doi.org/10.15277/bjd.2021.304

49. Jeyaventhan R, Gallen G, Choudhary P, Hussain S.  A Real-World Study of User Characteristics, Safety and Efficacy of Open-Source Closed-Loop Systems and Medtronic 670G. Diabetes Obes Metab. 2021 Aug. 23(8):1889-1994. Doi: 10.1111/dom.14439. [Epub 2021 Jun 9]. PMID: 33999488

48Søholm U, Broadley M, Choudhary P, Zaremba N, Amiel S, Speight J, Pouwer F. Does nocturnal hypoglycaemia really improve quality of life? Diabetologia 2021 Aug.64(8):1893-1894. Doi: 10.1007/s00125-021-05475-7. [Epub 2021 May 20]  PMID: 34014372

47.Bornstein SR, Guan K, Brunßen C, Mueller G, Kamvissi-Lorenz V, Lechler R, Trembath R, Mayr M, Poston L, Sancho R, IRTG Study Group, Ahmed S, Alfar E, Aljani B, Alves TC, Amiel S, Andoniadou CL, Bandral M, Belavgeni A, Berger I, Birkenfield A, Bonifacio E, Chavakis T, Chawla P, Choudhary P, Cujba AM, Delgadillo Silva LF, Demcollari T, Drotar DM, Duin S, El-Agroudy NN, El-Armouche A, Eugester A, Gado M, Gavalas A, Gelinsky M, Guirgus M, Hansen S, Hanton E, Hasse M, Henneicke H, Celler C, Hempel H, Hogstrand C, Hopkins D, Jarc L, Jones PM, Kamel M, Kämmerer S, King AJF, Kurzbach A, Lambert C, Latunde-Dada Y, Lieberam I, Liers J, Li JW, Linkermann A, Locke S, Ludwig B, Manea T, Maremonti F, Marinicova Z, McGowan BM, Mickunas M, Mingrone G, Mohanraj K, Morawietz H, Ninov N, Peakman M, Persaud SJ, Pietzsch J, Cachorro E, Pullen TJ, Pyrina I, Rubino F, Santambrogio A, Schepp F, Schlinkert P, Scriba LD, Siow R, Solimena M, Spagnoli FM, Speier S, Stavridou A, Steenblock C, Strano A, Taylor P, Tiepner A, Tonnus W, Tree T, Watt F, Werdermann M, Wilson M, Yusuf N, Ziegler CG.  The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease. Horm Metab Res. 2021 Mar;53(3):204-206. Doi: 10.1055/a-1377-6583. Epub 2021 Mar 2. PMID: 33652492

46. Diouri O, Cigler M, Vettoretti M, Mader JK, Choudhary P, Renard E, HYPO-RESOLVE Consortium. Hypoglycaemia detection and prediction techniques: A systematic review on the latest developments. Diabetes Metab Res Rev. 2021 Mar 15;e3449. Doi: 10.1002/dmrr.3449. Online ahead of print. PMID: 33763974

45. Forde H, Wilmot E, Choudhary P.  Letter to the editor. Diabet Med. 2021 Feb 22;e14546. Doi: 10.1111/dme.14546. Online ahead of print. PMID: 33616262

44. Stanton-Fay SH, Hamilton K, Chadwick P, Lorencatto F, Gianfrancesco C, de Zoysa N, Coates E, Cooke D, McBain H, Heller S, Michie S, DAFNEplus study group.  The DAFNEplus programme for sustained type 1 diabetes self management: Intervention development using the Behaviour Change Wheel. Diabet Med. 2021 Feb 22;e14548. Doi: 10.1111/dme.14548. Online ahead of print. PMID: 33617669

43. Nagi DK, Wilmot E, Owen K, Patel DC, Mills L, Rayman G, Winocour P, Aymen G, Patel R, Hambling C, Choudhary P.  ABCD position statement on risk stratification of adult patients with diabetes during COVID-19 pandemic. British Journal of Diabetes, Volume 21. Doi.org/10.15277/bjd.2021.282

42. Coates E, Amiel S, Baird W, Benaissa M, Brennan A, Campbell M, Chadwick P, Chater T, Choudhary P, Cooke D, Cooper C, Cross E, De Zoysa N, Eissa M, Elliott J, Gianfrancesco C, Good T, Hopkins D, Hui Z, Lawton J, Lorencatto F, Michie S, Pollard D, Schutter J, Scott E, Speight J, Stanton-Fay S, Taylor C, Thompson G, Totten N, Yardley L, Zaitcev A, Heller S.  Protocol for a cluster randomised controlled trial of the DAFNEplus (Dose Adjustment for Normal Eating) intervention compared with 5x1 DAFNE: A lifelong approach to promote effective self-management in adults with type 1 diabetes. BMJ Open. 2021 Jan 18;11(1):e040438. Doi: 10.1136/bmjopen-2020-040438. PMID: 33462097

41. Wilmot EG, Lumb A, Hammond P, Murphy HR, Scott E, Gibb FW, Platts J, Choudhary P. Time in range : A best practice guide for UK diabetes healthcare professionals in the context of the COVID-19 global pandemic. Diabetic Medicine 2021 Jan;38(1):e14433. Doi: 10.1111/dme.14433. Epub 2020 Nov 16.PMID: 33073388

2020

40. Leelarathna L, Choudhary P, Wilmot EG, Lumb A, Street T, Kar P, Ng SM. Hybrid closed-loop therapy: where are we in 2021? Diabetes Obes Metab 2020 Dec 2.Doi: 10.1111/dom.14273. [Online ahead of print]. PMID: 33269551

39. Nwokolo M, Amiel S, O’Daly O, Macdonald IA, Zelaya FO, Choudhary P.  Restoration of Hypoglycemia Awareness Alters Brain Activity in Type 1 Diabetes. Diabetes Care. 2020 Dec 16;dc201250. doi: 10.2337/dc20-1250. Online ahead of print. PMID: 33328282

38.Leelarathna L, Choudhary P, Wilmot E, Lumb A, Street T, Kar P, Ng SM.  Hybrid Closed-loop therapy: Where are we in 2021? Diabetes Obes Metab. 2020 Dec 2. doi: 10.1111/dom.14273. Online ahead of print. PMID: 33269551

37.Choudhary P, Wilmot E, Owen K, Patel D, Mills L, Rayman G, Winocour P, Ayman G, Patel R, Hambling C, Nagi D.  A roadmap to recovery: ABCD recommendations on risk stratification of adult patients with diabetes in the post-COVID-19 era. Diabet Med. 2020 Nov 23;e14462. doi: 10.1111/dme.14462. Online ahead of print. PMID: 33230813

36.Chandran SR, Zaremba N, Harrison A, Choudhary P, Cheah Y, Allan J, Debong F, Reid F, Treasure J, Hopkins D, Ismail K, Stadler M. Disordered eating in women with type 1 diabetes: Continuous glucose monitoring reveals the complex interactions of glycaemia, self-care behaviour and emotion. Diabet Med. 2020 Nov 3;e14446. doi: 10.1111/dme.14446. Online ahead of print. PMID: 33141942

35.Wilmot E, Lumb A, Hammond P, Murphy HR, Scott E, Gibb FW, PlattsJ, Choudhary P.  Time in range: a best practice guide for UK diabetes healthcare professionals in the context of the COVID-19 global pandemic. Diabet Med. 2020 Oct 19;e14433. doi: 10.1111/dme.14433. Online ahead of print. PMID: 33073388

34.Camerlingo N, Vettoretti M, Facchinetti A, Sparacino G, Mader JK, Choudhary P, Del Favero S.  An analytical approach to determine the optimal duration of continuous glucose monitoring data required to reliably estimate time in hypoglycaemia. Sci Rep. 2020 Oct 23;10(1):18180. doi: 10.1038/s41598-020-75079-5. PMID: 33097760

33.Forst T, Choudhary P, Schneider D, Linetzky B, Pozzilli P.  A practical approach to the clinical challenges in initiation of basal insulin therapy in people with type 2 diabetes.  Diabetes Metab Res Rev. 2020 Oct 23;e3418. doi: 10.1002/dmrr.3418. Online ahead of print.  PMID: 33098260

32.Sabbah S, Liew A, Brooks AM, Kundu R, Reading JL, Flat A, Counter C, Choudhary P, Forbes S, Rosenthal MJ, Rutter MK, Cairns S, Johnson P, Casey J, Peakman M, Shaw JA, Tree T.  Autoreactive T cell profiles are altered following allogeneic islet transplantation with alemtuzumab induction and re-emerging phenotype is associated with graft function. Am J Transplant. 2020 Aug 31. Online ahead of print. PMID: 32865886

31. YI Liew A, Holmes-Truscott E, Flatt AJ, Bennett D, Crookston R, Pimkova M, Casey J, Pernet A, Wood R, Chouhdary P, Forbes S, Rutter M, Rosenthal M, Johnson P, Shaw JA, Speight J.  Characterization of pre-transplant psychosocial burden in an integrated national islet transplant program. Islets. 2020 Aug 20;21-31. doi: 10.1080/19382014.2020.1736740. Online ahead of print. PMID: 32815765

30. Hussain S, Choudhary P, Hopkins D.  Type 1 diabetes and fasting in Ramadan: time to rethink classification of risk?  Lancet Diabetes Endocrinol. 2020 Aug;8(8):656-658. doi: 10.1016/S2213-8587(20)30219-9. PMID: 32707105

29. Nagi D, Choudhary P, Wilmot E, Winocour P.  Supporting people with diabetes during the COVID-19 pandemic without face-to-face appointments. Br J Diabetes 2020;20:1-4. doi.org/10.15277/bjd.2020.246.

28. Dowling L, Wilmot EG, Choudhary P.  Do-it-yourself closed-loop systems for people living with type 1 diabetes.  Diabet Med. 2020 May 18. doi: 10.1111/dme.14321. Online ahead of print. PMID: 32420640

27. Habteab A, Castaneda J, de Valk HW, Choudhary P, Bosi E, Lablanche S, de Portu S, Da Silva J, Vorrink L, Shin J, Cohen O.  Predicting factors associated with hypoglycemia reduction with automated predictive insulin suspension in patients at high risk of severe hypoglycemia: an analysis from the SMILE randomized trial.  Diabetes Technol Ther. 2020 Sep;22(9):681-685. doi: 10.1089/dia.2019.0495. PMID: 32412858

26. Shapey I, Summers A, Yiannoullou P, Khambalia H, Fullwood C, Hanley N, Casey J, Forbes S, Rosenthal M, Johnson P, Choudhary P, Bushnell J, Shaw J, Augustine T, Rutter M, van dellen D.  Donor insulin use predicts beta-cell function after islet transplantation.  Diabetes Obes Metab. 2020 May 25. Online ahead of print. PMID: 32452110

25. Sepulveda E, Poinhos R, Nata G, Carvalho D, Neves JS, Seixas D, Choudhary P, Vicente S, Amiel S.  Differentiating hypoglycemia awareness status from hypoglycemia experience in tools for measuring impaired awareness of hypoglycemia.  Diabetes Technol Ther. 2020 Mar 16;22(7):541-545. doi: 10.1089/dia.2020.0034. Online ahead of print.  PMID: 32175769

24. Chandran SR, Jacob P, Choudhary P. Baseline glucose variability and inter-week variability affects time to stability of continuous glucose monitoring (CGM) derived indices. Diabetes Technol Ther. 2020 Dec;22(12):937-942. doi: 10.1089/dia.2020.0011. Epub 2020 May 14. PMID: 32223562

23.  Chandran SR, Jacob P, Choudhary P. A systematic review of the effect of prior hypoglycaemia on cognitive function in type 1 diabetes.   Ther Adv Endocrinol Metab. 2020 Feb 14;11:2042018820906017. doi: 10.1177/2042018820906017. eCollection 2020. PMID: 32110374

22. Battelino T, Bosnyak Z, Danne T, Mukherjee B, Edelman S, Pilorget V, Choudhary P, Renard E, Bergenstal R. InRange: Comparison of the Second-Generation Basal Insulin Analogues Glargine 300 U/mL and Degludec 100 U/mL in Persons with Type 1 Diabetes Using Continuous Glucose Monitoring-Study Design.  Diabetes Ther. 2020 Apr;11(4):1017-1027. doi: 10.1007/s13300-020-00781-6. Epub 2020 Feb 25. PMID: 32100192.  Erratum in Diabetes Ther. 2020 Jul;11(7):1607-1608. doi: 10.1007/s13300-020-00820-2. PMID: 32361833 and Diabetes Ther. 2020 Aug;11(8):1907-1908. doi: 10.1007/s13300-020-00853-7. PMID: 32578133

21. Crabtree TSJ, Choudhary P, Hammond P, Lumb A, McLay A, Wilmot EG.  Health-care professional opinions of DIY artificial pancreas systems in the UK.   Lancet Diabetes Endocrinol. 2020 Mar;8(3):186-187. doi: 10.1016/S2213-8587(19)30417-6. PMID: 32085825

20. de Galan BE, McCrimmon RJ, Ibberson M, Heller SR, Choudhary P, Pouwer F, Speight J, Carlton J, Pieber TR, Rosilio M, Tack CJ, Müllenborn M; Hypo-RESOLVE Consortium. Reducing the burden of hypoglycaemia in people with diabetes through increased understanding: design of the Hypoglycaemia REdefining SOLutions for better liVEs (Hypo-RESOLVE) project.  Diabet Med. 2020 Jun;37(6):1066-1073. doi: 10.1111/dme.14240. Epub 2020 Feb 5. PMID: 31970814

19. Ruz-Maldonado I, Liu B, Atanes P, Pingitore A, Huang GC, Choudhary P, Persaud SJ.  The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling.  Cell Mol Life Sci. 2020 Jan 10. doi: 10.1007/s00018-019-03433-6. Online ahead of print. PMID: 31925452

18. Sayers SR, Beavil RL, Fine NHF, Huang GC, Choudhary P, Pacholarz KJ, Barran PE, Butterworth S, Mills CE, Cruickshank JK, Silvestre MP, Poppitt SD, McGill AT, Lavery GG, Hodson DJ, Caton PW.  Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes.  Diabetologia. 2020 Feb;63(2):313-323. doi: 10.1007/s00125-019-05029-y. Epub 2019 Nov 15. PMID: 31732790

2019

17. Chakranon P, Lai YK, Tang YW, Choudhary P, Khunti K, Lee SWH.  Distal technology interventions in people with diabetes: an umbrella review of multiple health outcomes.  Diabet Med. 2019 Oct 20. doi: 10.1111/dme.14156. Online ahead of print. PMID: 31631398

16. Nwokolo M, Amiel SA, O'Daly O, Byrne ML, Wilson BM, Pernet A, Cordon SM, Macdonald IA, Zelaya FO, Choudhary P.  Impaired Awareness of Hypoglycemia Disrupts Blood Flow to Brain Regions Involved in Arousal and Decision Making in Type 1 Diabetes. Diabetes Care. 2019 Nov;42(11):2127-2135. doi: 10.2337/dc19-0337. Epub 2019 Aug 27. PMID: 31455689

15. Choudhary P, de Portu S, Arrieta A, Castañeda J, Campbell FM.  Use of sensor-integrated pump therapy to reduce hypoglycaemia in people with Type 1 diabetes: a real-world study in the UK.  Diabet Med. 2019 Sep;36(9):1100-1108. doi: 10.1111/dme.14043. Epub 2019 Jun 30. PMID: 31134668

14.  Bosi E, Choudhary P, de Valk HW, Lablanche S, Castañeda J, de Portu S, Da Silva J, Ré R, Vorrink-de Groot L, Shin J, Kaufman FR, Cohen O; SMILE Study Group. Efficacy and safety of suspend-before-low insulin pump technology in hypoglycaemia-prone adults with type 1 diabetes (SMILE): an open-label randomised controlled trial.  Lancet Diabetes Endocrinol. 2019 Jun;7(6):462-472. doi: 10.1016/S2213-8587(19)30150-0. Epub 2019 Apr 29. PMID: 31047902

13. Nwokolo M, Amiel SA, O'Daly O, Byrne ML, Wilson BM, Pernet A, Cordon SM, Macdonald IA, Zelaya FO, Choudhary P.  Hypoglycemic thalamic activation in type 1 diabetes is associated with preserved symptoms despite reduced epinephrine.  J Cereb Blood Flow Metab. 2020 Apr;40(4):787-798. doi: 10.1177/0271678X19842680. Epub 2019 Apr 20.  PMID: 31006309

12.   Choudhary P, Campbell F, Joule N, Kar P; Diabetes UK.  A Type 1 diabetes technology pathway: consensus statement for the use of technology in Type 1 diabetes. Diabet Med. 2019 May;36(5):531-538. doi: 10.1111/dme.13933. Epub 2019 Apr 3. PMID: 30773681

2018-2015

11. Khan A, Choudhary P.  Investigating the Association Between Diabetes Distress and Self-Management Behaviors.  J Diabetes Sci Technol. 2018 Nov;12(6):1116-1124. doi: 10.1177/1932296818789721. Epub 2018 Aug 12.  PMID: 30101610

10. Dunn JT, Choudhary P , Teh MM, Macdonald I, Hunt KF, Marsden PK, Amiel SA.  The impact of hypoglycaemia awareness status on regional brain responses to acute hypoglycaemia in men with type 1 diabetes.  Diabetologia. 2018 Jul;61(7):1676-1687. doi: 10.1007/s00125-018-4622-2. Epub 2018 May 12. PMID: 29754288

9. Choudhary P, Amiel SA.  Hypoglycaemia in type 1 diabetes: technological treatments, their limitations and the place of psychology. Diabetologia. 2018 Apr;61(4):761-769. doi: 10.1007/s00125-018-4566-6. Epub 2018 Feb 8. PMID: 29423581

8. Todd P, Edwards F, Spratling L, Patel NH, Amiel SA, Sturt J, Choudhary P.  Evaluating the relationships of hypoglycaemia and HbA1c with screening-detected diabetes distress in type 1 diabetes.  Endocrinol Diabetes Metab. 2017 Dec 23;1(1):e00003. doi: 10.1002/edm2.3. eCollection 2018 Jan. PMID: 30815540

7. Slattery D, Amiel SA, Choudhary P.  Optimal prandial timing of bolus insulin in diabetes management: a review.  Diabet Med. 2018 Mar;35(3):306-316. doi: 10.1111/dme.13525. Epub 2017 Nov 6. PMID: 29044708

6. Sivasubramaniyam S, Amiel SA, Choudhary P. Proportion of daily capillary blood glucose readings required in the target range for target glycaemic control: shift of focus from target range to proportion in range.  Diabet Med. 2017 Oct;34(10):1456-1460. doi: 10.1111/dme.13438. Epub 2017 Aug 15. PMID: 28763121

5. James ML, Green L, Amiel SA, Choudhary P.  Evaluation of the Effect of Carbohydrate Intake on Postprandial Glucose in Patients With Type 1 Diabetes Treated With Insulin Pumps.  J Diabetes Sci Technol. 2016 Nov 1;10(6):1287-1293. Print 2016 Nov. PMID: 27137456

4. Choudhary P, Olsen BS, Conget I, Welsh JB, Vorrink L, Shin JJ.  Hypoglycemia Prevention and User Acceptance of an Insulin Pump System with Predictive Low Glucose Management.  Diabetes Technol Ther. 2016 May;18(5):288-91. doi: 10.1089/dia.2015.0324. Epub 2016 Feb 23. PMID: 26907513

3 Beato-Víbora P, Yeoh E, Rogers H, Hopkins D, Amiel SA, Choudhary P. Sustained benefit of continuous subcutaneous insulin infusion on glycaemic control and hypoglycaemia in adults with Type 1 diabetes.  Diabet Med. 2015 Nov;32(11):1453-9. doi: 10.1111/dme.12869. Epub 2015 Aug 19. PMID: 26213236

2. Yeoh E, Choudhary P, Nwokolo M, Ayis S, Amiel SA.  Interventions That Restore Awareness of Hypoglycemia in Adults With Type 1 Diabetes: A Systematic Review and Meta-analysis.  Diabetes Care. 2015 Aug;38(8):1592-609. doi: 10.2337/dc15-0102. PMID: 26207053

1 .Choudhary P, Rickels MR, Senior PA, Vantyghem MC, Maffi P, Kay TW, Keymeulen B, Inagaki N, Saudek F, Lehmann R, Hering BJ.  Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia.  Diabetes Care. 2015 Jun;38(6):1016-29. doi: 10.2337/dc15-0090. PMID:25998294

Research Grants

Current research grants:

1. 2017; 2018 – HYPORESOLVE [ HYPOglycemia : REdefining SOLutions for better liVEs– H2020 IMI 2 grant from EU [ Co-Investigator] – value €26.8 million [ KCL€1.2million]

2. 2017; JDRF Project grant: Using neuroimaging to understand the role of cognitions in restoring hypoglycemia awareness in adults with type 1 diabetes and impaired awareness of hypoglycemia;$653,199.41[ Principal investigator]

3. 2016; Immunological and Cellular Strategies in Metabolic Disease; IRTG grant from €5m [Co-Applicant]

4.     Beyond Education: A hypoglycemia awareness restoration program for people with type 1 diabetes and problematic hypoglycemia persisting despite optimised self-care (HARPdoc) JDRF Project grant $2.2 m [Co-Applicant].

5. Developing and trialling the DAFNE (Dose for Adjustment for Normal Eating) intervention. A lifelong approach to promote effective self-management in adults with type 1 diabetes. NIHR [Co-Applicant]

Previous grants:

1. 2014 Diabetes UK Project Grant: Pilot study for the evaluation of the safety of a novel immune isolating device for immunosuppression free islet transplantation £93231 [PI]

2.     2013 Diabetes UK Project Grant: Understanding cerebral responses to hypoglycaemia: a pathway to effective strategies to treat hypoglycaemia unawareness in Type 1 diabetes £410,922 [PI]

3.     Enhanced conversion of expanded criteria donor pancreases into successful clinical islet transplants [DRWF £37,000; Co-Applicant]

4.     Establishment of optimised biomedical and psychological measures to determine overall outcomes in islet transplantation recipients [£30,563 Co applicant]

5.     ANGELA03 STUDY – Closed loop insulin pump study in adults [co-PI]

6.     REPOSE study – investigating whether insulin pumps are more effective in treatment of type 1 diabetes than multiple insulin injections with combined with diabetes education

7.     2011 DRN collaborative grant for neuroimaging in diabetes £5000

8.     2007 JDRF Innovative Grant: Do sulphonylureas preserve cortical function during hypoglycaemia? $110,000

9.     2006: Diabetes UK Project grant: Can the use of Real Time Glucose Monitoring reverse hypoglycaemia unawareness? £123,900

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