2019 publications


713. Khunti N, Khunti N, Khunti K. Adherence to type 2 diabetes management. British Journal of Diabetes 2019 Dec.19 (2):99-104. DOI:https://doi.org/10.15277/bjd.2019.223

712. Khunti K, Giorgino F, Mauricio D, Berard L, Harris SB. The importance of the initial period of basal insulin titration in people with diabetes. Diabetes, Obesity and Metabolism 2020 May.22 (5): 722-733.DOI:10.1111/dom.13946 [Epub 2020 Jan 19]. PMID: 31865632

711. Stanulewicz N, Knox E, Narayanasamy M, Shivji N, Khunti K, Blake H. Effectiveness of Lifestyle Health Promotion Interventions for Nurses: A systematic Review. Int J Environ Res Public Health 2019 Dec18; 17(1). pii: E17. DOI: 10.3390/ijerph17010017. PMID: 31861367

710. Iglay K, Sawhney B, Fu AZ, Fernandes G, Crutchlow MF, Rajpathak S, Khunti K. Dose distribution and up-titration patterns of metformin monotherapy in patients with type 2 diabetes. Endocrinology, Diabetes & Metabolism 2019 Dec. 17;3(1):e00107. DOI : https://doi.org/10.1002/edm2.107.Ecollection 2020 Jan PMID: 31922032

709. Darko N, Dallosso H, Hadjiconstantinou M, Hulley K, Khunti K, Davies M. Qualitative evaluation of A Safer Ramadan, a structured education programme that addresses the safer observance of Ramadan for Muslims with Type 2 diabetes. Diabetes Research and Clinical Practice 2020 Feb.160:107979. DOI: 10.1016/j.diabres.2019.107979.[Epub 2019 Dec 12]. PMID: 31838120

708. Khunti K, Seidu S. Diabetes Care in the NHS through commissioning. Clinical Commissioning Groups Association journal 2019/2020.

707. Standl E, Khunti K, Hansen TB, Schnell O. The global epidemics of diabetes in the 21st century: Current situation and perspectives. European Journal of Preventive Cardiology 2019 Dec.26 (2): 7-14. DOI: 10.1177/2047487319881021. PMID: 31766915

706. Rowlands AV, Dawkins NP, Maylor B, Edwardson CL, Fairclough SJ, Davies MJ, Harrington DM, Khunti K, Yates T. Enhancing the value of accelerometer-assessed physical activity: meaningful visual comparisons of data-driven translational accelerometer metrics. Sports Medicine Open 2019 Dec. 5(1) 47.DOI: 10.1186/s40798-019-0225-9. PMID: 31808014

705.Lawson CA, Zaccardi F, McCann GP, Davies MJ, Kadam UT, Khunti K. Trends in cause-Specific Outcomes Among Individuals with Type 2 Diabetes and Heart Failure in the United Kingdom, 1998-2017. JAMA Netw Open 2019 Dec. 2(12):e1916447. DOI: 10.1001/jamanetworkopen.2019.16447. PMID: 31790564

704. Griffin SJ, Rutten GEHM, Khunti K, Witte DR, Lauritzen T, Sharp SJ, Dalsgaard EM, Davies MJ, Irving GJ, Vos RC, Webb DR, Wareham NJ, Sandbæk A. Long-term effects of intensive multifactorial therapy in individuals with screen-detected type 2 diabetes in  primary care: 10-year follow-up of the ADDITION-Europe cluster-randomised trial. The Lancet Diabetes and Endocrinology Dec 2019.7(12):925-937. DOI: 10.1016/S2213-8587(19)30349-3.PMID:31748169

703. Maula A, Kai J, Woolley AK, Weng S, Dhalwani N, Griffiths F, Khunti K, Kendrick D. Educational weight loss interventions in obese and overweight adults with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetic Medicine 2020 Apr.37 (4):623-635.DOI: 10.1111/dme.14193.[Epub 2019 Dec 22]. PMID: 31785118

702. Reeves K, Chan S, Marsh A, Gallier S, Wigley C, Khunti K, Lilford RJ. Implementation of research evidence in orthopaedics: a tale of three trials. BMJ Quality and Safety 2020 May.29(5): 374-381. DOI: 10.1136/bmjqs-2019-010056. [Epub 2019 Nov 27]. PMID: 31776198

701. Almulhem M, Susarla R, Alabdulaali L, Khunti K, Karamat MA, Rasiah T, Tahrani AA, Hanif W, Nirantharakumar K. The effect of Ramadan fasting on cardiovascular events and risk factors in patients with type 2 diabetes: A systematic review. Diabetes Research and Clinical Practice 2020 Jan.159:107918. DOI: 10.1016/j.diabres.2019.107918. [Epub 2019 Nov 9]. PMID: 31711857

700. Chetan MR, Miksza JK, Lawrence I, Anjana RM, Unnikrishnan R, Amutha A, Shanthi Rani CS, Jebarani S, Mohan V, Khunti K, Narendran P. The increased risk of microvascular complications in South Asians with type 1 diabetes is influenced by migration: results from the UK-India multi-ethnic migration study. Diabetic Medicine 2019 Nov13. DOI:10.1111/dme.14184. [Epub ahead of print]. PMID: 31721280

699. Zaccardi F, Franks PW, Dudbridge F, Davies MJ, Khunti K, Yates T. Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study. European Journal of Preventive Cardiology 2019 Nov12.DOI: 10.1177/2047487319885041. [Epub ahead of print]. PMID: 31711304

698. Brady EM, Hall AP, Baldry E, Chatterjee S, Daniels LJ, Edwardson C, Khunti K, Patel MI, Henson JJ, Rowlands A, Smith AC, Yates T, Davies MJ. Rationale and design of a cross-sectional study to investigate and describe the chronotype of patients with type 2 diabetes and the effect on glycaemic control: the CODEC study”. BMJ Open 2019 Nov 11.9(11) e027773. DOI: 10.1136/bmjopen-2018-027773. PMID: 31719069

697. Davies MJ, Kristunas CA, Alshreef A, Dixon S, Eborall H, Glab A, Huddlestone L, Hudson N, Khunti K, Martin G, Northern A, Patterson M, Pritchard R, Schreder S, Stribling B, Turner J, Gray LJ. The impact of an intervention to increase uptake to structured self-management education for people with type 2 diabetes mellitus in primary care (the embedding package), compared to usual care, on glycaemic control: study protocol for a mixed methods study incorporating a wait-list cluster randomised controlled trial. BMC Family Practice 2019 Nov 7.20(1):152. DOI: 10.1186/s12875-019-1038-0. PMID: 31699046

696. Argyridou S, Zaccardi F, Davies MJ, Khunti K, Yates T. Walking pace improves  all-cause and cardiovascular mortality risk prediction: A UK Biobank prognostic study. European Journal of Preventive Cardiology 2020 Jul. 27(10) :1036-1044 .DOI: 10.1177/2047487319887281. [Epub 2019 Nov 7]. PMID: 31698963

695. Rowlands AV, Fairclough SJ, Yates T, Edwardson CL, Davies M, Munir F, Khunti  K, Stiles VH. Activity Intensity, Volume, and Norms: Utility and Interpretation of    Accelerometer Metrics. Medicine and Science in Sports and Exercise 2019 Nov.51 (11):2410-2422 .DOI: 10.1249/MSS.0000000000002047. PMID: 31318713

694. Cheng A, Harris S, Giorgino F, Seufert J, Ritzel R, Khunti K, Lauand F, Melas-Melt L, Westerbacka J, Bosnyak Z, Rosenstock J. Similar glycaemic control and less hypoglycaemia during active titration after insulin initiation with glargine 300 units/mL and degludec 100 units/mL: A subanalysis of the BRIGHT study. Diabetes, Obesity and Metabolism 2020 Mar.22 (3):346-354. DOI: 10.1111/dom.13901. [Epub 2019 Dec 20] PMID: 31646724

693. Chakranon P, Lai YK, Tang YW, Choudhary P, Khunti K, Lee SWH. Distal technology  interventions in people with diabetes: an umbrella review of multiple health outcomes. Diabetic Medicine 2020 Dec.37 (12):1966-1976. DOI: 10.1111/dme.14156.[Epub 2019 Nov 12] PMID: 31631398

692. Miksza J, Zaccardi F, Kunutsor S, Seidu S, Davies MJ, Khunti K. Statins and risk of thromboembolism: A meta-regression to disentangle the efficacy-to effectiveness gap using observational and trial evidence. Nutrition, Metabolism and Cardiovascular Diseases 2019 Oct. 29 (10): 1023-1029. DOI: 10.1016/j.numecd.2019.06.022. PMID: 31383500

691. Selvarajah D, Kar D, Khunti K, Davies MJ, Scott AR, Walker J, Tesfaye S. Diabetic  peripheral neuropathy: advances in diagnosis and strategies for screening and early Intervention. The Lancet Diabetes & Endocrinology 2019 Dec.7 (12):938-948.DOI: 10.1016/S2213-8587(19)30081-6. [Epub 2019 Oct 14]. PMID: 31624024

690. Hart  HE, Ditzel K, Rutten GE, De Groot E, Seidu S, Khunti K, Vos RC. De-Intensification Of Blood Glucose Lowering Medication in People Identified As Being Over-Treated: A Mixed Methods Study. Patient Preference Adherence 2019 Oct.18(13):1775-1783.DOI: 10.2147/PPA.S208947. PMID: 31695339

689. Jones P, Mirkes EM, Yates T, Edwardson CL, Catt M, Davies MJ, Khunti K, Rowlands AV. Towards a Portable Model to Discriminate Activity Clusters from Accelerometer Data. Sensors Oct 2019 17.19(20).pii.E4504. DOI:10.3390/s19204504. PMID: 31627310

688. Chudasama YV, Zaccardi F, Gillies CL, Dhalwani NN, Yates T, Rowlands AV, Davies MJ, Khunti K. Leisure-time physical activity and life expectancy in people with cardiometabolic multimorbidity and depression. Journal of Internal Medicine 2020 Jan. 287(1):87-99.DOI: 10.1111/joim.12987. [Epub 2019 Nov 6]. PMID: 31602698

687. Jones P, Bibb R, Davies M, Khunti K, McCarthy M, Webb D, Zaccardi Prediction of Diabetic Foot Ulceration: The Value of Using Microclimate Sensor Arrays. Journal of Diabetes, Science and Technology 2020 Jan.14 (1):55-64.DOI: 10.1177/1932296819877194 [Epub 2019 Oct 9]. PMID: 31596145

686. Sargeant JA, Henson J, King JA, Yates T, Khunti K, Davies MJ. A Review of the Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Lean Body mass in Humans. Endocrinology and Metabolism 2019 Sep.34 (3):247-262. DOI: 10.3803/EnM.2019.34.3.247. PMID: 31565876

685. Crasto W, Morrison AE, Gray LJ, John E, Jarvis J, Brela J, Khunti K, Troughton J, Lawrence IG, McNally PG, Davies MJ. The Microalbuminuria Education Medication and Optimisation (MEMO) study: 4 years follow-up of multifactorial intervention in high-risk individuals with type 2 diabetes. Diabetic Medicine 2020 Feb.37(2):286-287 . DOI:10.1111/dme.14134 . [Epub 2019 Sep 23]. PMID: 31505051

684. Rowlands AV, Plekhanova T, Yates T, Mirkes EM, Davies M, Khunti K, Edwardson CL. Providing a Basis for Harmonization of Accelerometer-Assessed Physical activity Outcomes Across Epidemiological Datasets. Journal for the Measurement of Physical Behaviour 2019 Sep. 2(3):131-142.DOI: https://doi.org/10.1123/jmpb.2018-0073 .

683. Razieh C, Khunti K, Davies MJ, Edwardson CL, Henson J, Darko N, Comber A, Jones A, Yates T. Association of depression and anxiety with clinical, sociodemographic, lifestyle and environmental factors in South Asian and White European individuals at high risk of diabetes. Diabetic Medicine 2019 Sep.36 (9):1158-1167.DOI: 10.1111/dme.13986.[Epub 2019 Jun 30] PMID: 31081286

682. Lawson CA, Zaccardi F, Squire I, Ling S, Davies MJ, Lam CSP, Mamas MA, Khunti K, Kadam UT. 20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study. The Lancet Public Health 2019 Aug.4 (8):e406-e420. DOI: 10.1016/S2468-2667(19)30108-2. PMID: 31376859

681. Seidu S, Kunutsor SK, Khunti K. Association of circulating osteocalcin with cardiovascular disease and intermediate cardiovascular phenotypes: systematic review and meta-analysis. Scandinavian Cardiovascular Journal 2019 Dec.53 (6):286-295. DOI:10.1080/14017431.2019.1655166. [Epub 2019 Aug 22]. PMID: 31397589

680. Khunti K, Chen H, Cid-Ruzafa J, Fenici P, Gomes MB, Hammar N, Ji L, Kosiborod M, Pocock S, Shestakova MV, Shimomura I, Tang F, Watada H, Nicolucci A. Glycaemic control in patients with type 2 diabetes initiating second-line therapy: Results from the global DISCOVER study programme. Diabetes Obesity and Metabolism 2020 Jan.22(1):66-78. DOI: 10.1111/dom.13866. [Epub 2019 Oct 1 ] PMID: 31468637

679 Webb DR, Davies MJ, Jarvis J, Seidu S, Khunti K. The right place for Sulphonylureas today. Part of ‘Review the series: Implications of recent CVOTs in Type 2 diabetes Mellitus’. Diabetes Research and clinical practice 2019 Nov. DOI:10.1016/j.diabres.2019.107836. [Epub 2019 Aug 31]. PMID: 31479704

678. Gorely T, Harrington DM,  Bodicoat DH, Davies MJ,  Khunti K, Sherar LB, Tudor-Edwards R, Yates T, Edwardson CL. Process evaluation of the school-based Girls Active programme. BMC Public Health 2019 Aug 29.19 (1):1187. DOI: 10.1186/s12889-019-7493- 7.PMID: 31464592

677. Boels AM, Koning E, Vos RC, Khunti K, Rutten GEHM. Individualised targets for insulin initiation in type 2 diabetes mellitus-the influence of physician and practice: a cross sectional study in eight European countries. BMJ Open 2019 Aug 26. 9(8):e032040.DOI: 10.1136/bmjopen-2019-032040. PMID: 31455718

676. Edwardson CL, Henson J, Biddle SJH, Davies MJ, Khunti K, Maylor B, Yates T. activPAL and ActiGraph Assessed Sedentary Behaviour and Cardiometabolic Health Markers. Medicine and Science in Sports & Exercise 2020 Feb.52 (2):391-397. DOI: 10.1249/ MSS.0000000000002138. [Epub 2019 Aug]. PMID: 31479008

675. Farooqi A, Khunti K, Abner S, Gillies C, Morriss R, Seidu S. Comorbid depression and risk of cardiac events and cardiac mortality in people with diabetes: A systematic review and meta-analysis. Diabetes Research and Clinical Pract 2019 Aug 14:156. DOI: 10.1016/j.diabres.2019.107816. PMID: 31421139

674Gray L, Brady E, Albania O, Edwardson C, Harrington D, Khunti K, Miksza J, Raposo J,  Smith E, Vazeou A, Vergara I, Weihrauch-Blüher S, Davies M. Evaluation and refinement of the PRESTARt tool for identifying 12-14 year olds at high lifetime risk of developing type 2 diabetes compared to a clinicians assessment of risk: a cross-sectional study. BMC Endocr Disord 2019 Jul. 19(1):79. DOI: 10.1186/s12902-019-0410-3. PMID: 31345191

673. Nicolucci A, Charbonnel B, Gomes MB, Khunti K, Kosiborod M, Shestakova MV, Shimomura L,Watada H, Chen H, Cid-Ruzufa J, Fenici P, Hammar N, Surmont F, Tang F, Pocock S. Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: Results from the global DISCOVER study programme. Diabetes Obes Metab 2019 Jul. DOI: 10.1111/dom.13830. PMID: 31297947

672. Gulsin G, Kanagala P, Chan DCS, Cheng ASH, Athithan L, Graham-Brown MPM, Singh A, Yang J, LI Z, Khunti K, et al. Differential left ventricular and left atrial remodelling in heart failure with preserved ejection fraction patients with and without diabetes. Ther Adv Endocrinol Metab 2019 July. 10:2042018819861593. DOI: 10.1177/2042018819861593. PMID: 31308926

671. Kloecker DE, Zaccardi F, Baldry E, Davies MJ, Khunti K, Webb DR. Efficacy of Low- and Very-Low-Energy Diets in people with Type 2 Diabetes Mellitus: A systematic review and meta-analysis of interventional studies. Diabetes Obes Metab 2019 Jul. 21(7): 1695-1705. DOI: 10.1111/dom.13727. PMID: 30924575

670. Seidu S, Kunutsor SK, Topsever P, Hambling CE, Cos FX, Khunti K. Deintensification in older patients with type 2 diabetes: a systematic review of approaches, rates and outcomes. Diabetes Obes Metab 2019 Jul. 21(7): 1668-1679. DOI: 10.1111/dom.13724. PMID: 30938038

669. Jones P, Harrison M, Davies M, Khunti K, McCarthy M, Webb D, Berrington R. The biometric shoe: could 3D printed footwear and machine learning theoretically reduce complications from diabetes? The Diabetic Foot Journal 2019 Jun. 22(2); 28-31.

668. Morrison AE, Zaccardi F, Chatterjee S, Brady E, Doherty Y, Robertson N, Hadjiconstantinou M, Daniels L, Hall A, Khunti K, Davies MJ. Self-compassion, Metabolic Control and Health Status in Individuals with Type 2 Diabetes: A UK Observational Study. Expn Clin Endrocrinol Diabetes 2019 Jun. DOI: 10.1055/a-0897-3772. PMID: 31158896

667. Khunti K, Ji L, Medina J, Surmont F, Kosiborod M. Type 2 diabetes treatment and outcomes worldwide: A short review of the DISCOVER study programme. Diabetes Obes Metab 2019 Jun. DOI: 10.1111/dom.13817. PMID: 31215715

666. Seidu S, Kunutsor SK, Sesso HD, Gaziano JM, Buring JE, Roncaglioni MC, Khunti K. Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analysis of randomized controlled trials. Cardiovascular Diabetology 2019 June. 18 (1): 70. DOI: 0.1186/s12933-019-0875-4. PMID: 31159806

665. Chudasama YV, Khunti K, Zaccardi F, Rowlands A, Yates T, Gillies C, Davies M, Dhalwani N. Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study. BMC Med 2019 Jun. 17(1):108. DOI: 10.1186/s12916-019-1339-0. PMID: 31186007

664. Canivell S, Mata-Cases M, Real J, Franch-Nadal J, Viacho B, Khunti K, Gratacos M, Mauricio D. Glycaemic control after treatment intensification in patients with type 2 diabetes uncontrolled on two or more non-insulin antidiabetic drugs in a real-world setting. Diabetes Obes Metab 2019 Jun.21 (6): 1373-1380. DOI: 0.1111/dom.13663. Epub 2019 Mar 19. PMID: 30756446

663. Jones PJ, Bibb RJ, Davies MJ, Khunti K, McCarthy M, Fong DTP, Erbb D. A Fitting Problem: Standardising Shoe Fit Standards to Reduce Related Diabetic Foot Ulcers. Diabetes Res Clin Pract 2019 May. pii: S0168-8227(19)30624-2. DOI: 10.1016/j.diabres.2019.05.017. PMID: 31128134

662. Khunti S, Khunti K, Seidu S. Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia. Therapeutic Advances in Endocrinology and  Metabolism 2019 May. 10:2042018819844694. DOI: 10.1177/2042018819844694. PMID: 31105931

661. Tyrer F, Seidu S, Khunti K. Real-world evidence: improving quality in cardiometabolic medicine. Diabetes & Primary Care 2019 May. 21: 47–8. DOI: 10.1016/j.pcd.2018.10.002. PMID: 30446359

660. Seidu S, Kunutsor SK, Sesso HD, Gaziano JM, Buring JE, Roncaglioni MC, Khunti K. Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analysis of randomized controlled trials. Cardiovascular Diabetology. 2019 June:18:70. DOI: 0.1186/s12933-019-0875-4.

659. Meneghini LF, Mauricio D, Orsi E, Lalic NM, Cali AMG, Westerbacka J, Stella P, Candelas Dea C, Pilorget V, Perfetti R, Khunti K, DUNE Investigators. The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real-world setting. Diabetes Obes Metab. 2019 Jun: 21(6): 1429 – 1436. DOI: 10.1111/dom.13673. Epub 2019 Mar 28. PMID: 30768845

658Tyrer F, Seidu S, Khunti K. Real-world evidence: improving quality in cardiometabolic medicine. Diabetes & Primary Care 2019 May. 21: 47–8.

657. Zaccardi F, Nystrup Husemoen LL, Thorsted BL, Webb DR, Paul SK, Davies MJ, Khunti K. Selectivity of beta-blockers, cardiovascular and all-cause mortality in people with hypoglycaemia: An observational study. Nutr Metab Cardiovasc Dis. 2019 May: 29(5): 481-488. DOI: 10.1016/j.numecd.2019.01.006. PMID: 30940488

656Zaccardi F, Davies MJ, Khunti K, Yates T. Comparative relevance of physical fitness and adiposity on life expectancy: A UK Biobank observational study. 2019 May. DOI: 10.1016/j.mayocp.2018.10.029. Mayo Clin Proc. 2019 May: pii: S0025-6196(19)30063-1. DOI: 10.1016/j.mayocp.2018.10.029. PMID: 31079962

655. Chudasama YV, Khunti K, Zaccardi F, Rowlands A, Yates T, Gillies C, Davies M, Dhalwani N. Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study. BMC Med. 2019 Jun. 17(1):108. DOI:10.1186/s12916-019-1339-0. PMID: 31886007

654. Perrin N, Bodicoat DH, Davies MJ, Robertson N, Snoek FJ, Khunti K. Effectiveness of psychoeducational interventions for the treatment of diabetes-specific emotional distress and glycaemic control in people with type2 diabetes: A systematic review and meta-analysis. Prim Care Diabetes. 2019 Apr: pii: S1751- 9918(19)30145-7. DOI: 10.1016/j.pcd.2019.04.001. PMID: 31040069

653. Chatterjee S,  Khunti K,  Davies MJ. Authors’ Reply to Gough: “Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes”. Drugs. 2019 Apr: 79(6): 683-684. DOI: 10.1007/s40265-019-01093. PMID: 30919304

652. Spanopoulos D,Okhai H, Zaccardi F, Tebboth A, Barrett B, Busse M, Webb J, Khunti K.Temporal variation of renal function in people with type 2 diabetes mellitus: A retrospective UK clinical practice research datalink cohort study. Diabetes Obes Metab 2019 Aug. 21(8):1817-1823. DOI: 10.1111/dom.13734. [Epub 2019 May 6]. PMID: 30941882

651. Dhalwani NN, Zaccardi F, Waheed H, Papamargaritis D, Webb DR, Evison F, Lilford R, Davies MJ, Khunti K. Cardiovascular, cancer and mortality events after bariatric surgery in people with and without pre-existing diabetes: A nationwide study. Journal of Diabetes. 2019 Apr: 11(4): 265-272. DOI:10.1111/1753-0407.12851. PMID: 30191659

650. Coles B, Tyrer F, Khunti K. Letter to the Editor: Improving quality in cardiometabolic medicine real-world evidence. Primary Care Diabetes. 2019 Apr: 13(2); 188. DOI: 10.1016/j.pcd.2018.10.002. PMID: 30446359

649. Hussein H, Zaccardi F, Khunti K, Seidu S, Davies MJ, Gray LJ. Cardiovascular efficacy and safety of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: a systematic review and network meta-analysis. Diabet Med. 2019 Apr: 36(4): 444-452. DOI: 10.1111/dme.13898. [Epub ahead of print] PMID: 30653708

648. Khunti K, Jung H, Dans A, Held C, Dagenais GR, Yusuf S, Lonn E. Statin Use in Primary Prevention; a Simple Trial Based Approach Compared to Guideline Recommended Risk Algorithms for Selection of Eligible Patients. Canadian Journal of Cardiology Mar 2019. SO828-282X(19); 30188-6. DOI: 10.1016/j.cjca.2019.03.002

647. Rowe C, Sitch AJ, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Pellatt-Higgins T, Kalra PA, Khunti K et al. Biological variation of measured and estimated glomerular filtration rate in patients with chronic kidney disease. Kidney Int. 2019 Mar:  pii: S0085-2538(19)30274-1. DOI: 10.1016/j.kint.2019.02.021. PMID: 31084924

646. Patel P, Gupta P, Burns A, Mohamed AA, Cole R, Lane D, Seidu S, Khunti K. Biochemical Urine Testing of Adherence to Cardiovascular Medications Reveals High Rates of Nonadherence in People Attending Their Annual Review for Type 2 Diabetes. Diabetes Care 2019 Mar. pii: dc181453. DOI: 10.2337/dc18-1453. PMID: 30885952

645. Mohan V, Cooper ME, Matthews DR, Khunti K. The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm. Diabetes Ther. 2019 Mar: 10(Suppl 1):1-13. DOI: 10.1007/s13300-019-0573-y. Epub 2019 Feb 13. PMID: 30758834

644. Pintat S, Fenici P, Hammar N, Ji L, Khunti K et al. Eligibility of patients with type 2 diabetes for sodium–glucose cotransporter 2 inhibitor cardiovascular outcomes trials: a global perspective from the DISCOVER study. BMJ Open Diabetes Research and Care. Mar 2019: 7:e000627. DOI: 10.1136/bmjdrc-2018-000627.

643. Gomes MB, Rathmann W, Charbonnel B, Khunti K, Kosiborod M, Nicolucci A, Pocock SJ, Shestakova MV, Shimomura I, Tang F, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Ji L; DISCOVER investigators .Treatment of type 2 diabetes mellitus worldwide: Baseline patient characteristics in the global DISCOVER study. Diabetes Res Clin Pract 2019 Mar. 151:20-32. DOI: 10.1016/j.diabres.2019.03.024. PMID: 30904743

642. Dunkley AJ, Fitzpatrick C, Gray LJ, Waheed G, Heller SR, Frier BM, Davies MJ, Khunti K, Primary Care Diabetes Society. Incidence and severity of hypoglycaemia in type 2 diabetes by treatment regimen: A UK multi-site 12-month prospective observational study. Diabetes, Obes and Metab 2019 Mar. DOI: 10.1111/dom.13690. PMID: 30843327

641. Gulsin GS, Brady EM, Swarbrick DJ, Athithan L, Henson J, Baldry E, Mc Adam J, Marsh AM, Parke KS, Wormleighton JV, Levelt E, Yates T, Bodicoat D, Khunti K, Davies MJ, Mcann GP. Rationale, design and study protocol of the randomised controlled trial: Diabetes Interventional Assessment of Slimming or Training tO Lessen Inconspicuous Cardiovascular Dysfunction (the DIASTOLIC study). BMJ Open. 2019 Mar: 9(3): e023207. DOI: 10.1136/bmjopen-2018-023207 PMID: 30928925

640. Morrison A, Zaccardi F, Khunti K, Davies MJ. Causality between non–alcoholic fatty liver disease and risk of cardiovascular disease and type 2 diabetes: A meta-analysis with bias analysis. Liver International. 2019 Mar: 39(3): 557-567. DOI: 10.1111/liv.13994. PMID: 30358050

639. Bosch J, O'Donnell MJ, Swaminathan B, Lonn E, Sharma M, Dagenais GR, Diaz R, Khunti K, Lewis B, Avezum A, Held C, Keltai M, Reid C, Toff WD, Dans A, Leiter LA, Sliwa K, Lee SF, Janice M. Pogue, Hart RG, and Yusuf S. Effects of blood pressure and lipid lowering on cognition: Results from the HOPE-3 study. Neurology. 2019 Mar: 92(13): e1435-e1446. DOI: 10.1212/WNL.0000000000007174. PMID: 30814321

638. Khunti K, Seidu S. Therapeutic Inertia and the Legacy of Dysglycemia on the Microvascular and Macrovascular of Diabetes. Diabetes Care. 2019 Mar: 42(3):349-351. DOI: 10.2337/dci18-0030. PMID: 30787057.

637. Kunutsor SK, Seidu S, Khunti K. Response to commentary by Rhew and colleagues on: Depression, antidepressant use, and risk of venous thromboembolism: systematic review and meta-analysis of published observational evidence. Annals of Medicine. 2019 Feb: 51(1): 99-100. DOI: 10.1080/07853890 .2019.1581942. PMID: 30931634

636. Harrington DM, Davies MJ, Bodicoat D, Charles JM, Chudasama YV, Gorely T, Khunti K, Rowlands AV, Sherar LB, Tudor-Edwards R, Yates T, Edwardson CL. A school-based intervention ('Girls Active') to increase physical activity levels among 11- to 14-year-old girls: cluster RCT. Public Health Res. 2019 Feb: 7(5). DOI: 10.3310/phr07050.

635. Hambling CE, Khunti K, Cos X, Wens J, Martinez L, Topsever P, Del Prato S, Sinclair A, Schernthaner G, Rutten G, Seidy S. Factors influencing safe glucose-lowering in older adults with type 2 diabetes: A Person-centred Approach To Individualised (PROACTIVE) Glycemic Goals for older people A position statement of Primary Care Diabetes Europe. Prim Care Diabetes. 2019 Feb: pii: S1751-9918(18)30300. DOI: 10.1016/j.pcd.2018.12.005. PMID: 30792156

634. Roman M, Monaghan A, Serraino GF, Miller D, Pathak S, Lai F, Zaccardi F, Ghanchi A, Khunti K, Davies MJ, Murphy GJ. Meta-analysis of lifestyle changes for preoperative weight loss on surgical outcomes. British Journal of Surgery. 2019 Feb: 106(3): 181-189. DOI: 10.1002/bjs.11001. PMID: 30328098

633. Khunti K, Seidu S, Davies MJ. Should sodium glucose co-transporter-2 inhibitors be considered as first line oral therapy for people with type 2 diabetes?  Diabetes, Obesity and Metabolism. 2019 Feb: 21(2); 207-209. DOI: 10.1111/dom.13518. PMID: 30178516

632. Holt R, Gossage-Worrall R, Hind D, Bradburn M, McCrone P, Morris T, Edwardson C, Barnard K, Carey M, Davies MJ, Dickens C, Doherty Y, Etherington A, French P, Greenwood K, Kalidindi S, Khunti K, Laugharne R, Pendlebury J, Rathod S, Saxon D, Shiers D, Siddiqi N, Swaby L, Waller G, Wright S.  STEPWISE: Structured lifestyle education for people with schizophrenia, schizoaffective disorder and first episode psychosis: randomised controlled trial. The British Journal of Psychiatry. 2019 Feb: 214(2):63-73. DOI: 10.1192/bjp.2018.167. PMID: 30251622

631. Chatterjee S, Khunti K, Davies MJ. Correction to: Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes. Drugs. 2019 Feb: 79(2): 187. DOI: 10.1007/s40265-019-1063-2. PMID: 30706424

630. Chatterjee S, Khunti K, Davies MJ. Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes. Drugs. 2019 Feb: 79(2): 173-186. DOI: 10.1007/s40265-018-1048-6. PMID: 30623349

629. Thuraisingham S, Chondros P, Catchpool M, Dalziel K, Manski-Nankervis J-A, Speight J, Holmes-Truscott E, Audehm R, Chaing J, Blackberry I, O’Neal D, Khunti K et al. Update on the General Practice Optimising Structured Monitoring to Improve Clinical Outcomes in Type 2 Diabetes (GP-OSMOTIC) trial: statistical analysis plan for a multi-centre randomised controlled trial. Trials. 2019 Jan: 20(1):93. DOI: 10.1186/s13063-018-3126-1. PMID: 30700324

628. Biddle GJH, Edwardson CL, Rowlands AV, Davies MJ, Bodicoat DH, Hardeman W, Eborall H, Sutton S, Griffin S, Khunti K, Yates T. Differences in objectively measured physical activity and sedentary behaviour between white Europeans and south Asians recruited from primary care: cross-sectional analysis of the PROPELS trial. BMC Public Health. 2019 Jan:19(1): 95. DOI: 10.1186/s12889-018-6341-5.PMID: 30665392

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