Publications 2013

2013

Ahearne, M. J., Willimott, S., Pinon, L., Kennedy, B., Miall, F., Dyer, M. J. S., Wagner, S. (2013). Increased numbers of circulating cells resembling T follicular helper (Tfh) cells in chronic lymphocytic leukaemia and enhancement of CD154/IL-4 proliferation by the Tfh cytokine, IL-21. BRITISH JOURNAL OF HAEMATOLOGY, 161, 46.

Willimott, S., Beck, D., Ahearne, M. J., Adams, V. C., & Wagner, S. D. (2013). Cap-translation inhibitor, 4EGI-1 restores sensitivity to ABT-737 apoptosis through cap-dependent and independent mechanisms in chronic lymphocytic leukaemia.. Clin Cancer Res. doi:10.1158/1078-0432.CCR-12-2185

Dyer, M. J. S., Vogler, M., Wagner, S., Samuel, J., Pritchard, C., Macip, S., Jayne, S. (2013). Precision medicines for B-cell leukaemias and lymphomas; progress and potential pitfalls. British Journal of Haematology, 160(6), 725-733. doi:10.1111/bjh.12219

 

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Powerful pre-clinical platform for anti-cancer drug and biomarker discovery

Pre-clinical models that can accurately predict outcomes in the clinic are much sort after in the field of cancer drug discovery and development.  Read about how patient derived explants offer many advantages and are the powerful model of choice. A copy of the review, published in the British Journal of Cancer, is available by clicking this link: PDE Platform

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SEND Study Success

Congratulations to Chris Avery, who with collaborating colleagues published findings of the SEND study, a multi-centre randomised trial using two different surgical protocols for mouth cancer treatment.  A nationwide first for this type of trial, using real-world data.  The paper, published in the British Journal of Cancer, is available by clicking this link: SEND Paper

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Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

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Leicester Cancer Research Centre
Robert Kilpatrick Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
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T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

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