Dr Sara Busacca

Research Fellow

Room 411, Hodgkin Building,Dr Busacca
Leicester LE1 9HN
Tel: +44 (0) 116 252 5591
Email: sb580@le.ac.uk

Personal details

  • 2006: Master Degree in Chemistry and Pharmaceutical Technologies. University of Piemonte Orientale Amedeo Avogadro, Italy
  • 2006: Pharmacist qualification
  •  2007- 2009: PhD in Food and Pharmaceutical Biotechnology, University of Piemonte Orientale Amedeo Avogadro, Italy
  • 2009-2010 Research fellow, University of Piemonte Orientale, Italy
  • 2010-March 2012: Post-Doctoral research fellow, Queen’s University of Belfast, Northern Ireland
  • 2012- Present: Research associate, University of Leicester, UK

List of publications:



I have a particular interest in in understanding the molecular mechanisms that determine response to therapy in relapsed mesothelioma.

My current projects are focused on:

  • Genomic instability and markers of immune escape
  • BRCA1 as biomarker of response to spindle poisons
  • Synthetic lethal targeting of MTAP

In these studies, we use a combination of standard molecular biology technologies, patient samples, ex vivo models (explants), 3D cultures isolated from pleural fluids and next-generation sequencing.

External relationships:

  • 2016: Member of the local organizing committee for IMIG (International Mesothelioma Interest Group)
  • 2017: Member of the ECMC JING (junior investigators network group) steering committee

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Congratulations from the LCRC to the following postgraduate student(s) who successfully defended their PhD Viva's recently:

Sam Khan
Rebecca Allchin
Constantinos Alexandrou
Nabil Jaunbocus


Well done to Rachel Norman who was awarded a travel grant whilst at the Human Proteome Organization Conference in Florida, US.


In a recent exercise undertaken by the NCRI’s Clinical and Translational Radiotherapy Research Working Group (CTRad) Leicester was rated as internationally competitive/leading in the Radiation Biology Research domain, one of just four centres in the UK to achieve this rating in that domain.


New: Wellcome Trust Institutional Strategic Support Fund



Centre Health and Wellbeing Group
Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

Contact Details

Leicester Cancer Research Centre
Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
Leicester LE2 7LX

T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

(Please note this email address should not be used for clinical referrals or patient correspondence)

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