Dr Sara Busacca

Research Fellow

Room 411, Hodgkin Building,Dr Busacca
Leicester LE1 9HN
Tel: +44 (0) 116 252 5591
Email: sb580@le.ac.uk

Personal details

  • 2006: Master Degree in Chemistry and Pharmaceutical Technologies. University of Piemonte Orientale Amedeo Avogadro, Italy
  • 2006: Pharmacist qualification
  •  2007- 2009: PhD in Food and Pharmaceutical Biotechnology, University of Piemonte Orientale Amedeo Avogadro, Italy
  • 2009-2010 Research fellow, University of Piemonte Orientale, Italy
  • 2010-March 2012: Post-Doctoral research fellow, Queen’s University of Belfast, Northern Ireland
  • 2012- Present: Research associate, University of Leicester, UK

List of publications:



I have a particular interest in in understanding the molecular mechanisms that determine response to therapy in relapsed mesothelioma.

My current projects are focused on:

  • Genomic instability and markers of immune escape
  • BRCA1 as biomarker of response to spindle poisons
  • Synthetic lethal targeting of MTAP

In these studies, we use a combination of standard molecular biology technologies, patient samples, ex vivo models (explants), 3D cultures isolated from pleural fluids and next-generation sequencing.

External relationships:

  • 2016: Member of the local organizing committee for IMIG (International Mesothelioma Interest Group)
  • 2017: Member of the ECMC JING (junior investigators network group) steering committee

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SEND Study Success

Congratulations to Chris Avery, Honorary Associate Professor and Consultant Maxillofacial Surgeon, who with collaborating colleagues published the findings of the significant SEND study, a multi-centre randomised trial using two different surgical protocols for  mouth cancer treatment.  A nationwide first for this type of trial, using real-world data.  The paper, published in the British Journal of Cancer, is available by clicking this link: SEND Paper


Congratulations from the LCRC to Bethan Rogoyski and Aleksandra Bzura.

Bethan won best oral presentation at the AMS Midlands Academy of Medical Sciences Festival held on 27th March 2019 for her presentation on "Redeployment: The potential of repurposed drugs in preventing mesothelioma".

Aleks won the University PGR poster fair competition on 18th March 2019 for her poster entitled "New hope for treating mesothelioma cancer using PARP inhibitors".

Also, a huge well done to Grandezza Aburido who was in the semi-finals of the PGR poster fair.


New: Wellcome Trust Institutional Strategic Support Fund



Centre Health and Wellbeing Group
Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

Contact Details

Leicester Cancer Research Centre
Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
Leicester LE2 7LX

T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

(Please note this email address should not be used for clinical referrals or patient correspondence)

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