Professor G Don Jones

Professor of Cancer Radiation Research

Deputy Director, Leicester Cancer Research Centre

Fellow of the Higher Education Academy

Contact Details

Office: Room 1.26A, Robert Kilpatrick Clinical Sciences Building, University of Leicester, Leicester Royal Infirmary, Leicester LE2 7LX

Tel: +44 (0)116 223 1841

Email: gdj2@le.ac.uk

Research

The interests of my research team (the Radiation and Oxidative Stress group) may be summarised as: ‘Mechanisms, Measurement, Enhancement and Consequences of Radiogenic, Oxidative and Drug-Induced Damage to DNA’.

Radiotherapy and chemotherapy used either singly or in combination, are two of the principal modalities for the treatment of cancer. For radiation and many chemotherapeutic drugs, genomic DNA is the primary cellular target for the biological effects of these agents; indeed it is the DNA damage induced which is thought to be responsible for killing the of the cancer cells.

To better understand, judge and improve treatment efficacy, the purpose of our research is to explore the mechanisms to enhance these damaging interactions and to develop methods and biomarkers for the accurate measurement of DNA damage in vitro and in vivo; Importantly, we consider that assessing a biologically significant end-point (DNA damage formation and repair), which takes into account many of the governing molecular and genetic factors, offers the best chance of assessing, predicting and enhancing a patient's response to treatment. Emphasis is placed on studying clinically relevant doses (avoiding the uncertainty of extrapolation from higher doses) and on translational research themes with anticipated patient benefit.

Publications

You can view my publications on PubMed Publication Listing.

Career

  • BSc (Hons), Chemistry with Biochemistry, University of Leicester (1982)
  • MSc (Carbohydrate Chemistry - by research), University of Birmingham (1984)
  • PhD (Radiation Chemistry), University of Leicester (1987)
  • Postdoctoral Research Scientist, MRC Radiobiology Unit, Chilton, Didcot, Oxon (1987‐1991)
  • Postdoctoral Research Scientist, Division of Radiation Biology, Department of Radiology, University of California San Diego, La Jolla, California USA (1991-1994)
  • Visiting Research Scientist, Radiobiology Program, Cross Cancer Institute, Edmonton, Alberta Canada (1994-1995)
  • Centre Research Fellow, Centre for Mechanisms of Human Toxicity & Honorary Lecturer, Department of Chemistry, University of Leicester (1995-2000)
  • Lecturer, Department of Oncology, University of Leicester (2000-2002)
  • Senior Lecturer, Department of Oncology, University of Leicester (2002-2007)
  • Reader in Radiation Research, Department of Cancer Studies, University of Leicester (2007-2016)
  • Professor of Cancer Radiation Research, Department of Cancer Studies, University of Leicester (2016-to date)

CURRENT PROFESSIONAL ACTIVITY

  • Deputy Head of Department, Department of Cancer Studies, University of Leicester (2010 to date)
  • MSc Course Convenor, Molecular Pathology & Therapeutics of Cancer (MPTC) MSc, Department of Cancer Studies, University of Leicester (2014 to date)
  • Module Co-Lead, Biology of Cancer Special Study Module (BoC/SSM) (MB ChB Phase 1), Leicester Medical School, University of Leicester (2013 to date)
  • Radiation Research Lead, Cancer Research Leicester Centre & Chair, Radiation Research at Leicester Group (RR@Le), University of Leicester (2014 to date)

 ACADEMIC DISTINCTIONS 

  • Vice-President, President & Past-President, European Radiation Research Society (2011-2012, 2013-2014 & 2015-2016)
  • Vice-President & President, Association for Radiation Research (2006-2008 & 2008-2010)
  • Council Member, International Association for Radiation - serving consecutive terms of office (2011-2015 & 2015-2019)
  • Network Lead, NCRI CTRad UK Biomarker Network (2013 to date)
  • Committee Member, NCRI Clinical & Translational Radiotherapy Research Working Group (CTRad), (Basic Science - Workstream 1), serving 3 successive terms (2009-2011, 2012-2014, 2015-2017)
  • Finance Committee Lead & Nominations Committee Member, International Association for Radiation Research (2015)
  • Honorary Member, awarded by the Royal College of Radiologists for ‘Notable contributions made to Clinical Oncology in the United Kingdom’ (2012)
  • Examiner, Royal College of Radiologists, Faculty of Clinical Oncology, for the First Examination of the Fellowship in Clinical Oncology  (2005-2011)
  • Committee Member & Trustee, LH Gray Memorial Trust (2008 to date)
  • Treasurer & Membership Secretary, Association for Radiation Research (2005-2010)
  • Editorial Board Member, the journal Mutagenesis (2006 to 2016)
  • Editorial Board Member, the journal Clinical Oncology (2006-2012) and twice Guest Editor of the Special Editions ‘Advances in Clinical Radiobiology’ Parts 1 (2013) and 2 (2014)
     

Share this page:

NEWS

Inaugural Lecture

Prof DJL Jones

6.00pm 9/10/17

Details

---------------------------------

“Congratulations to Dr Ni Ni Moe Myint for successfully defending her PhD thesis on the 25th August 2017. Well done from all the students and staff of the Leicester Cancer Research Centre.”

---------------------------------

“All the staff in the Department of Cancer Studies, wish to send their congratulations to Dr Mehdi Masood who passed his MD on 30th June 2017.  Well done!”

--------------------------------

Congratulations to Dr Hussein Abbas on passing his PhD on 21st June 2017.  Well done from all the staff in the Department of Cancer Studies

--------------------------------

New: Wellcome Trust Institutional Strategic Support Fund

Details

---------------------------------

Centre Health and Wellbeing Group
Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

Contact Details

Leicester Cancer Research Centre
Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
Leicester LE2 7LX

T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

Maps and Directions

Sat Nav users: 
LE1 5WW 

Accessibility

DisabledGo logo

The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Robert Kilpatrick Clinical Sciences Building.