Professor Anne Thomas

Contact Details

Oncology Management Offices, Level 2
Osborne Building, Leicester Royal Infirmary
Leicester LE1 5WW

Tel: +44(0)116 258 7601
Email: at107@le.ac.uk

Personal assistant: Linda Willis, Email: LW59@le.ac.uk, Tel: 0116 258 7597

Personal details

  • BM (Southampton) July 1991
  • MRCP (UK) March 1994
  • PhD (Nottingham) May 1999
  • FRCP (London) May 2005

My clinical interests include the management of patients with upper and lower gastrointestinal malignancies including GIST.

I'm the Director of the Hope Against Cancer Clinical Trials Facility at the Leicester Royal Infirmary. This unit opened in 2012 and further expanded in 2020, houses the research teams and provides the clinical environment where all patients receiving unlicensed drugs are treated. More than 100 clinical studies are currently being run in a wide range of cancer types. I am Director of the Leicester Cancer Research and Experimental Cancer Medicine Centres.

Current Position(s) held

Professor of Cancer Therapeutics
Director, Hope Clinical Trials Facility, Leicester Royal Infirmary
Director, Leicester Experimental Cancer Medicine Centre

Awards/Positions of Esteem

  • Member of the Board of Examiners of the Speciality Certificate Exam in Medical Oncology, since 2009
  • Member of the Oesophago-gastric Sub-Group of the Upper GI Clinical Study Group of the NCRI, since 2009
  • Member of the Advanced Disease Sub-Group of the Colorectal Clinical Study Group of the NCRI, since 2009 (Past Chair 2014-2018)
  • Member of the Upper GI Clinical Study Group of the NCRI, since 2012
  • Member of the Colorectal Clinical Study Group of the NCRI, since 2014
  • Clinical specialist  to NICE on behalf of the RCP/NCRI/RCR/ACP/JCCO on four single technology appraisals
  • Member of the CRUK Experimental Medicine Expert Review Panel, since 2018
  • Member of the CRUK New Agents Committee, since 2019
  • Principal assessor for the TP Gunton grant for the British Medical Association, since 2012.

Research Interests

I have two major research interests:

  • The design and delivery of early phase clinical studies including chemoprevention strategies
  • Improving information exchange in oncology consultations

I am Chief Investigator for two national platform studies: Mesothelioma Stratified Therapy (MiST). A stratified multi-arm phase IIa clinical trial to enable accelerated evaluation of targeted therapies for relapsed malignant mesothelioma and COLO-PREVENT: A platform for developing colorectal cancer prevention strategies.  I am independent Chair of numerous independent Data Monitoring Committees for national studies and member of the MRC Trials Unit Steering Committee.  I work collaboratively with the scientists in the LCRC to facilitate translational research in a range of clinical areas, for example - exploring the role of ctDNA in the diagnosis of minimal residual disease.

Publications

My PubMed publications profile can be viewed here.

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Pre-clinical models that can accurately predict outcomes in the clinic are much sort after in the field of cancer drug discovery and development.  Read about how patient derived explants offer many advantages and are the powerful model of choice. A copy of the review, published in the British Journal of Cancer, is available by clicking this link: PDE Platform

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SEND Study Success

Congratulations to Chris Avery, who with collaborating colleagues published findings of the SEND study, a multi-centre randomised trial using two different surgical protocols for mouth cancer treatment.  A nationwide first for this type of trial, using real-world data.  The paper, published in the British Journal of Cancer, is available by clicking this link: SEND Paper

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Centre Health and Wellbeing Group
Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

Contact Details

Leicester Cancer Research Centre
Robert Kilpatrick Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
Leicester LE2 7LX

T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

(Please note this email address should not be used for clinical referrals or patient correspondence)

Maps and Directions

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LE1 5WW

Accessibility

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The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Robert Kilpatrick Clinical Sciences Building.

Seminars

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