Professor Andy Gescher

Emeritus Professor of Biochemical ToxicologyAndy Gescher

Contact Details

  • Tel: 0116 223 5830
  • Office: CSMM, Level 5 Offices, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX

Education

  • Pharmazeutisches Staatsexamen (BSc), Undergraduate training at the Department of Pharmacy, University of Frankfurt, West Germany.
  • PhD “Polarographic studies on pharmacologically relevant sulfoximides”, Dept. of Pharmacy, University of Würzburg, West Germany
  • D.Sc., Aston University, Birmingham. 

Research Interests

  • Utilisation of translational research in laboratory to take new agents into clinic - achieved with resveratrol, anthocyanins, curcumin, silibinin.
  • Development of methods for assessing response and predicting chemopreventive activity.
  • Preclinical and early clinical development of novel cancer chemopreventive agents.
  • Development of resveratrol, curcumin, silibinin and anthocyanins.
  • Determining optimal intervention schedules – investigation of dose-response relationships for dietary and pharmacological doses of chemopreventive agents.
  • Development of long-term in vitro models for screening agents.
  • Structure optimisation of colorectal cancer chemopreventive flavones.
  • Combining dietary chemopreventive agents with chemotherapeutic regimens for the treatment of cancer.

Publications

To view Professor Gescher's publications, please use the link below:

PubMed Publication Listing

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NEWS

Powerful pre-clinical platform for anti-cancer drug and biomarker discovery

Pre-clinical models that can accurately predict outcomes in the clinic are much sort after in the field of cancer drug discovery and development.  Read about how patient derived explants offer many advantages and are the powerful model of choice. A copy of the review, published in the British Journal of Cancer, is available by clicking this link: PDE Platform

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SEND Study Success

Congratulations to Chris Avery, who with collaborating colleagues published findings of the SEND study, a multi-centre randomised trial using two different surgical protocols for mouth cancer treatment.  A nationwide first for this type of trial, using real-world data.  The paper, published in the British Journal of Cancer, is available by clicking this link: SEND Paper

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Centre Health and Wellbeing Group
Join up for a walk on the park Friday lunchtime - details here.

More information from Jenny McNair jm65@le.ac.uk

Contact Details

Leicester Cancer Research Centre
Robert Kilpatrick Clinical Sciences Building
University of Leicester
Leicester Royal Infirmary
Leicester LE2 7LX

T: +44 (0) 116 252 3170
E: cancerstudies@le.ac.uk

(Please note this email address should not be used for clinical referrals or patient correspondence)

Maps and Directions

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LE1 5WW

Accessibility

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The University of Leicester is committed to equal access to our facilities. DisabledGo has a detailed accessibility guide for the Robert Kilpatrick Clinical Sciences Building.

Seminars

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