Dr Cordula Stover
Lecturer in Immunology
Contact Details
Lab 211, MSB
Telephone: (+44) (0)116 252 5032
E-mail: cms13@le.ac.uk
Research Interests
- Role of properdin in tumour growth and metastasis
- Properdin in diet induced vascular inflammation
- Role of properdin in instructing cell phenotypes in murine infectious disease models
- Role of properdin in septicemia and shock
- Inflammatory component of ischemic and proteinuric kidney disease
- Clinical collaborations
Selected Recent Publications
Kouser L, Abdul-Aziz M, Nayak A, Stover CM, Sim RB, Kishore U. Properdin and factor HL opposing players on the alternative complement pathway "see-saw". Front Immunol 2013;4:93
Ruseva MM, Vernon KA, Lesher AM, Schwaeble WJ, Ali YM, Botto M, Cook T, Song W, Stover CM, Pickering MC. Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency. J Am Soc Nephrol 2013;24(1):43-52
Dimitrova P, Ivanovska N, Belenska L, Milanova V, Schwaeble WJ, Stover CM. Abrogated RANKL expression in properdin-deficient mice is associated with better outcome from collagen-antibody-induced arthritis. Arthritis Res Ther 2012;14(4):R173
Ali YM, Lynch NJ, Haleem KS, Fujita T, Endo Y, Hansen S, Holmskov U, Takahashi K, Stahl GL, Dudler T, Girija UV, Wallis R, Kadioglu A, Stover CM, Andrew PW, Schwaeble WJ. The lectin pathway of complement activation is a critical component of the innate murine response to pneumococcal infection. PLoS Pathog 2012;8(7):e1002793
Schwaeble WJ, Lynch NJ, Clark JE, Marber M, Samani NJ, Ali YM, Dudler T, Parent B, Lhotta K, Wallis R, Farrar CA, Sacks S, Lee H, Zhang M, Iwaki D, Takahashi M, Fujita T, Tedford CE, Stover CM. Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury. Proc Natl Sci USA 2011;108(18):7523-8
Stover C. Dual role of complement in tumour growth and metastasis [Review]. Int J Mol Med 2010;25(3):307-13
Staley KG, Kuehni CE, Strippoli MP, McNally T, Silverman M, Stover C. Properdin in childhood and its association with wheezing and atopy. Pediatr Allergy Immunol 2010;21(4 pt 2):e787-91
Dimitrova P, Ivanovska N, Schwaeble C, Gyurkovska V, Stover C. The role of properdin in murine zymosan-induced arthritis. Mol Immunol 2010;47(7-8):1458-66
