Our translational research is underpinned by the purpose-built Hope Clinical Trials Facility directed by Professor Anne Thomas. This Facility was established in 2012 with substantial investment being provided by our local cancer charity Hope Against Cancer and additional financial support from the University of Hospitals Leicester NHS Trust

Hope Clinical Trials FacilityThe Trials Facility has 8 beds and is fully equipped to deliver all phases of studies from complex first in man to phase III trials. The facility incorporates a small laboratory with appropriate built-in monitoring and pharmacy preparation area.

The clinical trials team focuses on a number of cancers, including: thoracic, colorectal, hepatobiliary, pancreatic and upper gastro-intestinal cancers as well as haematological malignancies. The team supports all phases of clinical trial, but have specific expertise in early phase trials of novel anticancer agents, running first in man trials and pharmacokinetic studies.

We have invested in a responsive staffing infrastructure to ensure we can deliver our clinical trials programmes across multiple tumour types and now have in excess of 100 clinical studies open at any one time. Since the opening of the facility we have seen a ~47% increase in recruitment of patients to NRCN and commercial studies and have strong partnerships with multiple industrial partners, Cancer Research UK and other organisations.

ECMC LogoThe clinical trials team also benefits from close interactions with the Leicester’s Experimental Cancer Medicine Centre (ECMC), whose staff help consent relevant patients and collect samples as required by the clinical protocol, and offer IT support on the development of databases that are crucial for the successful management of clinical trials and tissue collection.


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