Publications

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Publications for last 10 years only 

2011  2010   2009   2008   2007   2001-2006  

2011

Baines RJ, Brunskill NJ. Tubular toxicity of proteinuria. Nat Rev Nephrol 2011;7(3):177-80

2010

Hills C, Brunskill NJ, Squires PE. C-peptide as a therapeutic tool in diabetic nephropathy. Am J Nephrol 2010;31(5):389-97

Hills C, Willars GB, Brunskill NJ. Proinsulin C-peptide antagonizes the profibrotic effects of TGF-beta 1 via up-regulation of retionoic acid and HGF-related signaling pathways. Mol Endocrinol 2010;24(4):822-31

2009

Hills CE, Brunskill NJ. C-peptide and its intracellular signalling. Rev Diabet Stud 2009;6(3):138-47

Hills CE, Brunskill NJ. Cellular and physiological effects of C-peptide. Clin Sci (Lond) 2009;116(7):565-74

Hills CE, Al-Rasheed N, Willars GB, Brunskill NJ. C-peptide reverses TGF-beta1-induced changes in renal proximal tubular cells: implications for treatment of diabetic nephropathy. Am J Physiol Renal Physiol 2009;296(3):F614-21

Baker R, Robertson N, Rogers S, Davies M, Brunskill N, Khunti K, Steiner M, Williams M, Sinfield P. The National Institute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLARHC) for Leicestershire, Northamptonshire and Rutland (LNR): a programme protocol. Implement Sci 2009;12;4:72 

2008

Baines R, Brunskill NJ. The molecular interactions between filtered proteins and proximal tubular cells in proteinuria. Nephron Exp Nephrol 2008;110(2):e67-71

Chana RS, Sidaway JE, Brunskill NJ. Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. Am J Nephrol 2008;28(5):823-30

Hills CE, Brunskill NJ. Intracellular signalling by c-peptide. Exp Diabetes Res 2008;2008:635158

2007

Eyre J, Ioannou K, Grubb BD, Saleem MA, Mathieson PW, Brunskill NJ, Christensen EI, Topham PS. Statin-sensitive endocytosis of albumin by glomerular podocytes. Am J Physio Renal Physiol 2007;292(2):F674-81

2001-2006

Al-Rasheed NM, Willars GB, Brunskill NJ. C-peptide signals via galpha i to protect against TNF-alpha-mediated apoptosis of opossum kidney proximal tubular cells. J Am Soc Nephrol 2006;17(4):986-95

Brunskill NJ. Albumin signals the coming of age of proteinuric nephropathy. J Am Soc Nephrol 2004;15:504-505.

Chana RS, Lewington AJ, Brunskill NJ. Differential effects of peroxisome proliferator activated receptor-gamma (PPARgamma) ligands in proximal tubular cells: thiazolidineodiones are partial PPARgamma agonists. Kidney Int 2004;65(6):2081-90

Sidaway JE, Davidson RG, McTaggart F, Orton TC, Scott RC, Smith GJ, Brunskill NJ. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells. J Am Soc Nephrol 2004;15(9):2258-65

Al-Rasheed NM Chana RS, Baines RJ, Willars GB, Brunskill NJ. Ligand-independent activation of peroxisome prooliferator-activated receptor-gamma by insulin and c-peptide in kidney proximal tubular cells-dependent on phosphatidylinositol 3-kinase activity. J Biol Chem 2004;279(48):49747-54

Van Der Helm-Van Mil AH, Smith AC, Pouria S, Tarelli E, Brunskill NJ, Eikenboom HC. Immunoglobulin A multiple myeloma presenting with Henoch-Schonlein purpura associated with reduced sialylation of IgA1. Br J Haematol 2003; 122:915-917.

Arici M, Chana R, Lewington A, Brown J, Brunskill NJ. Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. J Am Soc Nephrol 2003;14:17-27.

Arici M, Brown J, Williams M, Harris KP, Walls J, Brunskill NJ. Fatty acids carried on albumin modulate proximal tubular cell fibronectin production: a role for protein kinase C. Nephrol Dial Transplant 2002;17:1751-1757.

Thomas ME, Harris KP, Walls J, Furness PN, Brunskill NJ. Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria. Am J Physiol Renal Physiol 2002;283:F640-F647.

West SD, Brunskill NJ. Complications associated with influenza infection. Postgrad Med J 2002;78(100):107-8.

Lewington AJ, Arici M, Harris KP, Brunskill NJ, Walls J. Modulation of the renin-angiotensin system in proteinuric renal disease: are there added benefits? Nephrol Dial Transplant 2002;16:885-888. [Review]

Brunskill NJ. Albumin handling by proximal tubular cells: mechanisms and mediators. Nephrol. Dial. Transplant. 15 Suppl 6, 39-40. [Review]

Brunskill NJ. Albumin and proximal tubular cells--beyond endocytosis. Nephrol Dial Transplant 2000;15:1732-1734. [Review]

Zickerman AM, Allen AC, Talwar V, Olczak SA, Brownlee A, Holland M, Furness PN, Brunskill NJ, Feehally J. IgA myeloma presenting as Henoch-Schonlein purpura with nephritis. Am J Kidney Dis 2000;36:E19.

Dixon R, Brunskill NJ. Albumin stimulates p44/p42 extracellular-signal-regulated mitogen-activated protein kinase in opossum kidney proximal tubular cells. Clin. Sci. (Lond) 2000;98;295-301.

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Contact Details

Department of Infection, Immunity and Inflammation,
Maurice Shock Medical Sciences Building,
University Road,
Leicester, LE1 9HN, UK 

General enquiries to:
Alison Brown

T:+44 (0)116 252 2951
F:+44 (0)116 252 5030

Postgraduate enquiries to: 
Susan Kapadia (PhD)

Frances Tarte (MSc)

Erasmus and Study Abroad Co-ordinator:

Professor Peter Andrew

T: +44 (0)116 252 2951

Other contact details can be found in People

Head of Department: Professor Peter Andrew