Brad Manktelow

Senior Research Fellow

CONTACT DETAILS

Department of Health Sciences
22-28 Princess Road West
University of Leicester
Leicester LE1 6TP

Tel: 00 44 116 2525496

RESEARCH INTERESTS:

I am currently the statistician for The Infant Mortality and Morbidity Studies.

My particular research interests centre on the statistical issues arising from research in neonatal and paediatric medicine.

RESEARCH PROJECTS

Co-investigator

Current

HQIP: £2,145,000. Maternal, Newborn and Infant Clinical Outcome Review Programme (MBRRACE-UK). Kurinczuk JJ, Knight M, Gray R, Redshaw M, Draper ES, Field DJ, Manktelow BN, Smith LK, Bevan C, Scott J, Brocklehurst P, Neilson J, Kenyon S, Shakespeare J, Modi N.
NIHR Programme Grant: £1,906,572. Towards reducing variations in infant mortality and morbidity: a population approach. Field D, Draper E, Manktelow B, Smith L, Boyle E, Taylor D, Marlow N, Petrou S, Maubach P.
NIHR Research Method Fellowship and Internship (Round 2): £91,000. Manktelow B, Baker R.
NIHR Research Method Fellowship and Internship (Round 3): £91,000. Manktelow B, Baker R.
NIHR Research for Patient Benefit: £245,125. The hidden risks of preterm birth: How should we follow-up vulnerable babies? Boyle E, Johnson S, Armstrong N, Petrou S, Manktelow B, Field D, Wolke D.
NIHR SDO: £133,468. The right cot, at the right time, at the right place. Use of Neonatal Survey data and computer simulation technology to improve design and organisation of neonatal care networks. Pitt MA, Gibson A, Allen M, Manktelow BN, Allwood ACL, Spencer A, Prosser S.
Neonatal and Paediatric Pharmacists Group: £26,251. Intermittent intravenous vancomycin dosage in children aged over 1 month: What dose should we start with and how should we adjust dosage to get optimum trough levels? Nash C, Gooding N, Mulla H, Manktelow B.

Previous

NIHR Research Method Fellowship and Internship (Round 1): £135,422. Manktelow B, Field D. (2009-2012)
NIHR Research for Patient Benefit: £51,774. Assessing the bioequivalence of unlicensed liquid Captopril formulations used in the treatment of children with heart failure: a randomised, open-label, single-centre, crossover study in healthy adults. Mulla H, Pandya H, Tofeig M, Samani N, Tanna S, Tuleau C, Manktelow B. (2007-2009)
Yorkshire & The Humber SCG: £23,959. Confidential Enquiry for North Neonatal Network. Draper ES, Field DJ, Manktelow BN. (2008-2010)
NHS Executive West Midlands (via North Staffs HA): £265,058. Follow‑up of children treated with neonatal CNEP in Stoke on Trent. Marlow N, Vyas H, Draper ES, Manktelow B. (2002-2004)
University Hospitals of Leicester NHS Trust and Leicester Primary Care Research Alliance: £17,801. Neonatal intensive care outcomes and resource utilisation in Trent: 2001-2003 compared with 1991-1993. Dorling J, Lamming C, Draper E, Manktelow B, Bohin S, Field D.

TEACHING ACTIVITIES

I contribute to the teaching of the MSc in Medical Statistics and to the Health and Disease in Populations module of the MBChB

SELECTED PUBLICATIONS

Evans TA, Seaton SE, Manktelow BN. Quantifying the potential bias when directly comparing Standardised Mortality Ratios for in-unit neonatal mortality. PLoS ONE 2013;8(4):e61237.

Hinchliffe SR, Seaton SE, Lambert PC, Draper ES, Field DJ, Manktelow BN. Modelling time to death or discharge in neonatal care: an application of competing risks. Paediatric and Perinatal Epidemiology 2013;27(4):426-433.

Manktelow BN, Seaton SE, Field DJ, Draper ES. Population based estimates of in-unit survival for very preterm babies. Pediatrics 2013;131:e425-e432.

Seaton SE, King S, Manktelow BN, Draper ES, Field DJ. Babies born at the threshold of viability: changes in survival and workload over 20 years. Archives of Disease in Childhood Fetal & Neonatal Edition 2013;98(1):F15-F20.

Seaton SE, Lingsma HF, Steyerberg EW, Manktelow BN. The statistical power to detect outlying performance using funnel plots. BMJ Quality and Safety. [In press]

Smith LK, Draper ES, Manktelow BN, Pritchard C, Field DJ. Comparing regional infant death rates: the influence of preterm births <24 weeks of gestation. Archives of Disease in Childhood Fetal & Neonatal Edition 2013;98(2):F103-F107.

Manktelow BN, Seaton SE. Specifying the probability characteristics of funnel plot control limits: an investigation of three approaches. PLoS ONE 2012;7(9):e45723. doi:10.1371/journal.pone.0045723

McGrother CW, Donaldson MMK, Thompson J, Wagg A, Tincello DG, Manktelow BN. Etiology of overactive bladder: A diet and lifestyle model for diabetes and obesity in older women. Neurourology and Urodynamics 2012;31(4):487-495. doi: 10.1002/nau.21200.

Mohammed MA, Manktelow BN, Hofer TP. Comparison of four methods for deriving hospital standardised mortality ratios from a single hierarchical logistic regression model. Statistical Methods in Medical Research. Published Online First: 6 November 2012 doi: 10.1177/0962280212465165.

Schuit E, Hukkelhoven CWPM, Manktelow BN, Papatsonis DNM, de Kleine MJK, Draper ES, Steyerberg EW, Vergouwe Y. Prognostic models for stillbirth and neonatal death in very preterm birth: a validation study. Pediatrics 2012;129(1):1-8.

Schuit E, Hukkelhoven CWPM, Manktelow BN, Papatsonis DNM, de Kleine MJK, Draper ES, Steyerberg EW, Vergouwe Y. Voorspellen van sterfte bij zeer premature kinderen. Nederlands Tijdschrift voor Geneeskunde 2012;156:A4846.

Seaton SE, Field DJ, Draper ES, Manktelow BN, Smith GCS, Springett A, Smith LK. Socioeconomic inequalities in the rate of stillbirths by cause: a population based study. BMJ Open 2012;2:e001100 doi:10.1136/bmjopen-2012-001100

Seaton SE, Manktelow BN. The probability of being identified as an outlier with commonly used funnel plot control limits for the Standardised Mortality Ratio. BMC Medical Research Methodology 2012;12:98.

Mulla H, Hussain N, Tanna S, Lawson G, Manktelow BN, Tuleu C, Samani NJ, Pandya HC. Assessment of liquid captopril formulations used in children. Archives of Disease in Childhood 2011;96(3):293-296.

Rattihalli RR, Lamming CR, Dorling J, Manktelow BN, Bohin S, Field DJ, Draper ES. Neonatal intensive care outcomes and resource utilisation in the former Trent region: 2001-2003 compared with 1991-1993. Archives of Disease in Childhood Fetal & Neonatal Edition 2011:96(5);F329-F334.

Seaton SE, Yadav KD, Field DJ, Khunti K, Manktelow BN. Birthweight centile charts for UK born babies of South Asian ethnic origin. Neonatology 2011;100(4):398-403.

Manktelow B, Draper ES, Field C, Field DJ. Estimates of length of neonatal stay for very premature babies in the UK. Archives of Disease in Childhood Fetal & Neonatal Edition 2010;95(4):F288-F292.

Manktelow BN, Draper ES, Field DJ. Predicting neonatal mortality among very preterm infants: a comparison of three versions of the CRIB score. Archives of Disease in Childhood Fetal & Neonatal Edition 2010;95(1):F9-F13.

ManktelowBN, LalMK, FieldDJ, Sinha SK. Antenatal corticosteroids and neonatal outcomes according to gestational age: a cohort study. Archives of Disease in Childhood Fetal & Neonatal Edition 2010;95(2):F95-F98.

Smith LK, Manktelow BN, Draper ES, Springett A, Field DJ. Nature of socioeconomic inequalities in neonatal mortality: a population based study. BMJ 2010;341:c6654

Manktelow B, Potter JF. Interventions in the management of serum lipids for preventing stroke recurrence [review update]. Cochrane Database of Systematic Reviews 2009; Issue 3.

Manktelow BN, Potter JF. Interventions in the management of serum lipids for preventing stroke recurrence. Stroke 2009; 40(11):e622-e623.

Smith LK, Draper ES, Manktelow BN, Field DJ. Socioeconomic inequalities in survival and provision of care: a population based study of very preterm infants. BMJ 2009;339:b4702.

Kamoji VM, Dorling JS, Manktelow B, Draper ES, Field DJ. Antenatal umbilical Doppler abnormalities: an independent risk factor for early onset neonatal necrotizing enterocolitis in premature infants. Acta Paediatrica 2008;97(3):327-331

Field D, Bajuk B, Manktelow BN, Vincent T, Dorling J, Tarnow-Mordi W, Draper ES, Henderson Smart D. Geographically based investigation of the influence of very-preterm births on routine mortality statistics from the UK and Australia. Archives of Disease in Childhood Fetal & Neonatal Edition 2008; 93(3):F212-F216

Field DJ, Dorling JS, Manktelow BN, Draper ES. Survival of extremely premature babies in a geographically defined population: prospective cohort study of 1994-1999 compared with 2000-2005. BMJ 2008; 336:1221-1223

Milligan DWA, Carruthers P, Mackley B, Ward Platt MP, Collingwood Y, Wooler L, Gibbons J, Draper E, Manktelow BN. Nursing workload in UK tertiary neonatal units. Archives of Disease in Childhood 2008;93(12):1059-1064

Tiruvoipati R, Bangash M, Manktelow B, Peek GJ. Efficacy of prone ventilation in adult patients with acute respiratory failure: A meta-analysis. Journal of Critical Care 2008; 23(1):101-110

Tiruvoipati R, Pandya H, Manktelow B, Smith J, Dodkins I, Elbourne D, Field D. Referral pattern of neonates with severe respiratory failure for extracorporeal membrane oxygenation. Archives of Disease in Childhood Fetal & Neonatal Edition 2008;93(2):F104-F107

Cusack JM, Manktelow BN, Field DJ. Impact of service changes on neonatal transfer patterns over 10 years. Archives of Disease in Childhood Fetal & Neonatal Edition 2007;92(3):F181-184

Draper ES, Zeitlin J, Field DJ, Manktelow BN, Truffert P. Mortality patterns among very preterm babies: a comparative analysis of two European regions in France and England. Archives of Disease in Childhood Fetal & Neonatal Edition 2007;92(5):F356-F360

Sabri K, Manktelow B, Anwar S, Field DJ, Woodruff G. Ethnic variations in the incidence and outcome of severe ROP. Canadian Journal of Ophthalmology 2007;42(5):727-730

Smith LK, Draper ES, Manktelow BN, Dorling JS, Field DJ. Socio-economic inequalities in very pre term birth rates. Archives of Disease in Childhood Fetal & Neonatal Edition 2007;92(1):F11-F14

Smith LK, Draper ES, Manktelow BN, Field DJ. Deprivation and infection among spontaneous very preterm births. Obstetrics & Gynecology 2007;110:325-329

Telford K, Waters L, Vyas H, Manktelow BN, Draper ES, Marlow N. Respiratory outcome in late childhood following neonatal continuous negative pressure ventilation. Archives of Disease in Childhood Fetal & Neonatal Edition 2007;92(1):F19-F24

Kamoji VM, Dorling JS, Manktelow B, Draper ES, Field DJ. Extremely growth retarded babies: is there a viable centile? Pediatrics 2006;118(2):758-763

Telford K, Waters L, Vyas H, Manktelow BN, Draper ES, Marlow N. Outcome after neonatal continuous negative-pressure ventilation: follow-up assessment. Lancet 2006;367:1080-1085

Dorling JS, Field DJ, Manktelow B. Neonatal disease severity scoring systems. Archives of Disease in Childhood Fetal & Neonatal Edition 2005;90(1):F11-F16

Davis PJ, Firmin RK, Manktelow B, Goldman AP, Davis C, Smith J, Cassidy J, Shekerdemian LS. Long-term outcome following extracorporeal membrane oxygenation for congenital diaphragmatic hernia? The UK experience. Journal of Pediatrics 2004;144(3):309-315

Draper ES, Manktelow BN, McCabe C, Field DJ The potential impact on costs and staffing of introducing clinical networks and British Association of Perinatal Medicine standards to the delivery of neonatal care. Archives of Disease in Childhood Fetal and Neonatal Edition 2004;89(3):F236-F240

Hameed B, Shyamanur K, Kotecha S, Manktelow BN, Woodruff G, Draper ES, Field D. Trends in the incidence of severe retinopathy of prematurity in a geographically defined population over a 10 year period. Pediatrics 2004;113(6):1653-1657

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