Laura Gray, BSc (Hons), MSc, PhD.
Lecturer of Population & Public Health Sciences
& Associate Senior Statistician at Leicester Clinical Trials Unit
Department of Health Sciences (Thurs)
Tel: 00 44 116 2525491
Diabetes Research Centre / Leicester Clinical Trials Unit (Mon-Weds, Fri)
Leicester Diabetes Centre (Broadleaf)
Leicester General Hospital
Tel: 00 44 116 2584043
- Design and analysis of randomised clinical trials
- Systematic reviews and meta analysis
- Risk score development and validation
2013-2016: Diabetes UK Innovators in Diabetes Programme member
2013-Present: Panel member East Midlands NIHR Research for Patient Benefit funding Stream
2008-2013: Editorial board member for Significance, Royal Statistical Society Journal
2008-2013: Committee member of the Young Statistician Section of the Royal Statistical Society
POSTGRADUATE SUPERVISION AND TEACHING ACTIVITIES
2012-2016: Shaun Barber – Full time PhD student, primary supervisor
2011-2013: Postgraduate tutor
2011-Present: Deputy Ethics Officer
Module Lead for the Quantitative Methods Module of the MRes Applied Health Research.
I teach and supervise dissertations on the following courses: MSc Medical Statistics, MRes Applied Health Research and MSc Diabetes
RESEARCH DEGREE SUPERVISION
I would be interested in supervising PhD study in the following areas:
- Design and analysis of clinical trials
- Development and validation of risk scores
- Evidance synthesis
To learn more see http://www2.le.ac.uk/study/research/phd/health-sciences
Gray L.J, Leigh T, Davies MJ, Patel N, Stone M, Bonar M, Badge R, Khunti K (2013) Systematic review of the development, implementation and availability of smart-phone applications for assessing Type 2 diabetes risk. Diabet Med;30(6):758-60.
Gray L.J, Barros H, Raposo L, Khunti K, Davies MJ, Santos AC (2012) The development and validation of the Portuguese risk score for detecting type 2 diabetes and impaired fasting glucose. Prim Care Diabetes. 2013 Apr;7(1):11-8.
Gray L.J, Khunti K, Edwardson C, Goldby S, Henson J, Morris DH, Sheppard D, Webb D, Williams S, Yates T, Davies MJ (2012) Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance. Diabetologia 55 (12), 3238-3244.
Gray L.J, Khunti K, William S, Goldby S, Troughton J, Yates T, Gray A, Davies MJ (2012) Let's Prevent Diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation. Cardiovascular Diabetology, 11:56.
Khunti K, Gray L.J, Skinner T, Carey M, Realf K, Dallosso H, Fisher H, Campbell M, Heller S, Davies MJ (2012) Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow up of a cluster randomized controlled trial in primary care. BMJ.344:e2333.
Gray L.J, Cooper N, Dunkley A, Warren F, Ara R, Abrams K, Davies M.J, Khunti K, Sutton A (2012) A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity. Obes Rev. 13(6):483-98.
Gray L.J, Davies MJ, Hiles S, Taub N, Webb DR, Srinivasan BT, Khunti K (2012) Detection of Impaired Glucose Regulation and/or Type 2 Diabetes Mellitus, using primary care electronic data, in a multiethnic UK community setting. Diabetologia. 55(4):959-66.
Webb DR, Khunti K, Gray L.J, Srinivasan BT, Farooqi A, Wareham N, Griffin SC, Davies MJ; for the ADDITION-Leicester study group (2012) Intensive multifactorial intervention improves modelled 5-year coronary heart disease risk in screen-detected Type 2 diabetes mellitus: a cluster randomized controlled trial. Diabet Med. (4):531-40
Gray L.J, Yates T, Davies MJ, Brady E, Webb DR, Sattar N, Khunti K (2011) Defining obesity cut-off points for migrant south Asians. PLoS One. 6(10):e26464.
Webb DR, Gray L.J, Khunti K, Srinivasan B, Taub N, Campbell S, Barnett J, Farooqi A, Echouffo-Tcheugui JB, Griffin SJ, Wareham NJ, Davies MJ (2011) Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: the ADDITION-Leicester study. Diabetologia. 54(9):2237-46.
Webb D.R, Gray L.J, Khunti K, Campbell S, Dallosso H, Davies M.J (2011) Contrasting cardiovascular risk profiles and prescribed cardio-protective therapies in newly-diagnosed type 2 diabetes identified through screening and standard practice. Diabetes Res Clin Pract. 91(3):280-5.
Gray L.J, Tringham J.R, Davies M.J, Webb D.R, Jarvis J, Skinner T.C, Farooqi A.M, Khunti K (2010) Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: a cross-sectional study. Vascular Health and Risk Management, 6:837-42.
Carter P, Gray L.J, Troughton J, Khunti K, Davies MJ (2010) Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta analysis. British Medical Journal 2010;341:c4229
Gray L.J, Taub NA, Khunti K, Gardiner E, Hiles S, Webb DR, Srinivasan BT, Davies MJ (2010) The Leicester Risk Assessment score for detecting undiagnosed Type 2 diabetes and impaired glucose regulation for use in a multiethnic UK setting. Diabetic Medicine. 27(8) 887-895.
Gray L.J, Ali M, Lyden P.D, Bath P.W.M, for the VISTA Collaboration (2009) Interconversion of the National Institute of Health Stroke Scale (NIHSS) and Scandinavian Stroke Scale (SSS) in patients with acute stroke. Journal of Stroke Cerebrovascular Diseases.18(6):466-8.
Gray L.J, Bath P.M.W, Collier T, The Optimising Analysis of Stroke Trials (OAST) Collaboration (2008) Should stroke trials adjust functional outcome for baseline prognostic factors? Stroke. 40: 888-894.
Bath P.M.W, Geeganage C, Gray L.J, Collier T, Pocock S (2008) Optimising the analysis of stroke prevention trials: converting dichotomous vascular outcomes into ordinal measures. Stroke. 39(10):2817-23.
Gray L.J, Bath P.M.W, Collier T, The Optimising Analysis of Stroke Trials (OAST) Collaboration (2008) Calculation of sample size for stroke trials assessing functional outcome: comparison of binary and ordinal approaches. International Journal of Stroke. 3:78-84.
Gibson C.L, Gray L.J, Bath P.M.W, Murphy S.P (2008) Progesterone for the treatment of experimental brain injury. Brain. 131: 318-28.
Gray L.J, Sprigg N, Bath P.M.W, Boysen G, De Deyn P, Leys D, O’Neill D, Ringelstein EB, for the TAIST Investigators (2007) Sex differences in quality of life in stroke survivors: data from the ‘Tinzaparin in Acute Ischaemic Stroke Trial’ (TAIST). Stroke. 38 (11):2960-4.
Bath P.M.W, Gray L.J, Collier T, Pocock S, Carpenter J, The Optimising Analysis of Stroke Trials (OAST) Collaboration (2007) Can we improve the statistical analysis of stroke trials? Statistical reanalysis of functional outcomes in stroke trials. Stroke. 38: 1911-1915.
Gray L.J, Sprigg N, Rashid P.A, Willmot M, Bath P.M.W (2006) Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke Journal of Stroke and Cerebrovascular Diseases. 15(6): 245-249.
Gibson C.L, Gray L.J, Murphy, S.P, Bath P.M.W (2006) Estrogen for experimental ischemic stroke; a systematic review. Journal of Cerebral Blood flow metabolism. 26(9):1103-13.
Gray L.J, Sprigg N, Bath P.M.W, Sørensen P, Lindenstrøm E, Boysen G, De Deyn P.P, Friis P, Leys D, Marttila R, Olsson J-E, O’Neill D, Ringelstein B, MD; van der Sande J-J, Turpie A.G.G, for the TAIST Investigators (2006) Significant variation in mortality and functional outcome after acute ischaemic stroke between western countries: data from the ‘Tinzaparin in Acute Ischaemic Stroke Trial’ (TAIST). Journal of Neurology, Neurosurgery and Psychiatry 77: 327-333.
Bath P.M.W, Gray L.J (2005) Hormone replacement therapy and subsequent stroke: a meta analysis. British Medical Journal, 330, 342