Keith Abrams

Professor of Medical Statistics and   
Head of Unit, Studies of Health Populations and Society

CONTACT DETAILS

• The development and application of Bayesian methods in healthcare evaluation.
• Systematic reviews and meta-analysis.
• The joint modeling of longitudinal and time-to-event data.

He has considerable experience of undertaking pragmatic RCTs and systematic reviews in a variety of settings, including cardiology, gastroenterology, oncology and reproductive medicine.

SELECTED PUBLICATIONS

Draper ES, Rankin J, Tonks AM, Abrams KR, Field DJ, Clarke M, Kurinczuk JJ. Recreational drug use: a major risk factor for gastroschisis? Am J Epidemiol. 2008;167(4):485-91

Riley RD, Thompson JR, Abrams KR. An alternative model for bivariate random-effects meta-analysis when the within-study correlations are unknown. Biostatistics. 2008;9(1):172-86

Lambert PC, Billingham LJ, Cooper NJ, Sutton AJ, Abrams KR. Estimating the cost-effectiveness of an intervention in a clinical trial when partial cost information is available: a Bayesian approach. Health Econ. 2008;17(1):67-81

Cooper NJ, Lambert PC, Abrams KR, Sutton AJ. Predicting costs over time using Bayesian Markov chain Monte Carlo methods: an application to early inflammatory polyarthritis. Health Econ. 2007;16(1):37-56

Riley RD, Abrams KR, Lambert PC, Sutton AJ, Thompson JR. An evaluation of bivariate random-effects meta-analysis for the joint synthesis of two correlated outcomes. Stat Med. 2007;26(1):78-97

Bravo Vergel Y, Palmer S, Asseburg C, Fenwick E, de Belder MA, Abrams K, Sculpher MJ. Is primary angioplasty cost-effective in the UK? Results of a comprehensive decision analysis. Heart. 2007;93(10):1238-1243.

Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L.Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry. J Clin Epidemiol. 2008;61(10):991-6

Williams KS, Assassa RP, Gillies CL, Abrams KR, Turner DA, Shaw C, Haslam J, Mayne C, McGrother CW. A randomized controlled trial of the effectiveness of pelvic floor therapies for urodynamic stress and mixed incontinence. BJU Int. 2006;98(5):1043-50

Fenwick E, Palmer S, Claxton K, Sculpher M, Abrams K, Sutton A. An iterative Bayesian approach to health technology assessment: application to a policy of preoperative optimization for patients undergoing major elective surgery. Med Decis Making. 2006;26(5):480-96.

Peters JL, Sutton AJ, Jones DR, Rushton L, Abrams KR. A systematic review of systematic reviews and meta-analyses of animal experiments with guidelines for reporting. J Environ Sci Health B. 2006;41(7):1245-58.

Wailoo AJ, Sutton AJ, Cooper NJ, Turner DA, Abrams KR, Brennan A, Nicholson KG. Cost-effectiveness and value of information analyses of neuraminidase inhibitors for the treatment of influenza. Value Health. 2008;11(2):160-71.

Gillies CL, Lambert PC, Abrams KR, Sutton AJ, Cooper NJ, Hsu RT, Davies MJ, Khunti K.Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis. BMJ. 2008;336:1180-5

Asseburg C, Bravo Vergel Y, Palmer SJ, Fenwick E, de Belder MA, Abrams KR, Sculpher MJ. Assessing the effectiveness of primary angioplasty compared to thrombolysis and its relationship to time delay: a Bayesian evidence synthesis. Heart. 2007;93(10):1244-50

Toff WD, Jones CI, Ford I, Pearse RJ, Watson HG, Watt SJ, Ross JA, Gradwell DP, Batchelor AJ, Abrams KR, Meijers JC, Goodall AH, Greaves M. Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activation. JAMA. 2006;295(19):2251-61.

Alder N, Fenty J, Warren F, Sutton AJ, Rushton L, Jones DR, Abrams KR. Meta-Analysis of Mortality and Cancer Incidence among Workers in the Synthetic Rubber-Producing Industry. Am J Epidemiol. 2006;164(5):405-20

Sutton AJ, Cooper NJ, Jones DR, Lambert PC, Thompson JR, Abrams KR. Evidence-based sample size calculations based upon updated meta-analysis. Stat Med. 2007;26(12):2479-500.

Ades AE, Sculpher M, Sutton A, Abrams K, Cooper N, Welton N, Lu G. Bayesian methods for evidence synthesis in cost-effectiveness analysis. Pharmacoeconomics. 2006;24(1):1-19

Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Comparison of two methods to detect publication bias in meta-analysis. JAMA. 2006;295(6):676-80  

Turner DA, Wailoo AJ, Cooper NJ, Sutton AJ, Abrams KR, Nicholson KG. The cost-effectiveness of influenza vaccination of healthy adults 50-64 years of age. Vaccine. 2006;24(7):1035-43.

Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu RT, Khunti K. Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis. BMJ. 2007;334:299-302.