2012 Publications

2012

Davies MJ, Htike ZZ. Exenatide: Role in management of type 2 diabetes and associated cardiovascular risk factors. Clinical Practice. January 2012, 9;1:23-38, doi:2217/CPR.11.132.

Yates T, Khunti K, Wilmot E, Brady E, Webb D, Srinivasan BT, Henson J, Talbot D, Davies MJ. Self-reported sitting time and markers of inflammation, insulin resistance and adiposity. Am J Prev Med. 2012 Jan;42(1):1-7, doi:10.1016/j.amepre.2011.09.022. PMID 22176839

Ara R, Blake L, Gray L, Hernandez M, Crowther M, Dunkley A, Warren F, Jackson R, Rees A, Stevenson M, Abrams K, Cooper N, Davies MJ, Khunti K, Sutton A. What is the clinical effectiveness of using drugs in treating obese patients in primary care? A systematic review. Health Technology Assessment 2012;16(5):iii-xiv, 1-195, doi:10.3310/hta16050. PMID 22340890

Carey M, Khunti K, Davies M. Structured education in diabetes: A review of the evidence. Diabetes and Primary Care 14(3):154-162 2012.

Carter P, Khunti K, Davies MJ. Dietary recommendations for the prevention of T2DM? What are they based on? J Nutr Metab. 2012:847202. doi: 10.1155/2012/847202. PMID 22315675

Yates T, Davies MJ, Khunti K. Obesity and chronic disease in younger people: An unfolding crisis. Br J Gen Pract 2012;62(594):4-5, doi:10.3399/bjgp12X616201. PMID 22520657

Bluher S, Markert J, Herget S, Yates T, Davies MJ, Muller G, Waldow, Schwarz PEH. Who should we target for diabetes prevention and diabetes risk reduction? Curr Diab Rep. 2012 Apr;12(2):147-156 PMID 22298028

Schwarz PEH, Greaves C, Linstrom J, Yates T, Davies MJ. Non-pharmacological intervention for the prevention of type 2 diabetes mellitus. Nat Rev Endocrinol, 2012 Jan 17;8(6);363-73, doi:10.1038/nrendo.2011.232. PMID 22249519

Gholap N, Davies MJ, Mostafa S, Squire I, Khunti K. A simple strategy for screening for glucose intolerance, using glycated haemoglobin, in individuals admitted with acute coronary syndrome. Diabet Med. 2012 Jul;29(7):838-43, doi:10.1111/j.1464-5491.2012.03643.x. PMID 22417234

Htike ZZ, Khunti K, Davies MJ. A review of exenatide: Optimising glycaemic control and associated cardiovascular risk factors in type 2 diabetes. Diabetes Ther. 2012 Nov;3(1):1-16, doi:10.1007/s13300-012-0003-x. PMID 22422427

Eborall H, Stone M, Aujla N, Taub N, Davies MJ, Khunti K. Influences on the uptake of diabetes screening: a qualitative study in primary care. Br J Gen Pract 2012 Mar;62(596):204-11, doi:10.3399/bjgp12X630106. PMID 22429438

Gray LJ, Davies MJ, Hiles S, Taub NA, Webb DR, Srinivasan BT, Khunti K. Detection of Impaired Glucose Regulation and/or Type 2 Diabetes Mellitus, using primary care electronic data, in a multiethnic UK community setting. Diabetologia. 2012 Apr;55(4):959-66, doi:10.1007/s00125-011-2432-x. PMID 22231125

Patel N, Stone MA, Chauhan A, Davies MJ, Khunti K. Insulin initiation and management in people with type 2 diabetes in an ethnically diverse population: the healthcare provider perspective. Diabet Med. 2012 Oct;29(10):1311-6, doi:10.1111/j.1464-5491.2012.03669.x. PMID 22486745

Gray LJ, Khunti K, Williams S, Goldby S, Troughton J, Yates T, Gray A, Davies MJ. Let’s Prevent Diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multiethnic UK population with screen detected impaired glucose regulation. Cardiovasc Diabetol. 2012 May 20;11(1):56, doi:10.1186/1475-2840-11-56. PMID 22607160

Davies MJ, Speight J. Patient-reported outcomes in trial of incretin-based therapies in patients with type 2 diabetes. Diabetes Obesity & Metabolism. 2012 Oct;14(10):882-92 PMID 22420869

Khunti K, Gray LJ, Skinner T, Carey ME, Dallosso H, Fisher H, Campbell M, Heller S, Davies MJ. Effectiveness of a diabetes education and self-management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care . BMJ 2012 Apr 26;344:e2333. doi: 10.1136/bmj.e2333. PMID 22539172

Khunti K, Gillies C, Taub N, Mostafa S, Hiles S, Abrams K, Davies MJ. A comparison of cost per case detected of screening strategies for Type 2 Diabetes Mellitus and Impaired Glucose Regulation: modelling study. Diabetes Res Clin Pract. 2012 Sep;97(3):505-13, doi:10.1016/j.diabres.2012.03.009. PMID 22554999

Edwardson C, Gorely T, Biddle S, Wilmot E, Khunti K, Gray LJ, Yates T, Davies MJ. Association of sedentary behaviour with metabolic syndrome: A meta-analysis. PLoS One. 2012;7(4)e34916, doi:10.1371/journal.pone.0034916. EPUB. PMID 22514690

Speight J, Khagram, Davies MJ. Generic and diabetes-specific well-being in the AT.LANTUS Follow-on study: further psychometric validation of the W-BQ28 indicates its utility in research and clinical practice in Type 2 diabetes in the UK. Diab Med. 2012 Sep;29(9):e34553, doi:10.1111/j.1464-5491.2012.03702.x. PMID 22540936

Brady EM, Davies MJ, Hall AP, Talbot DC, Dick JL, Khunti K. An investigation into the relationship between sleep-disordered breathing, the metabolic syndrome, cardiovascular risk profiles, and inflammation between South Asians and Caucasians residing in the United Kingdom. Metab Syndr Relat Disord 10(2):152-158 Apr 2012, doi:10.1089/met.2011.0073. PMID 22283669

Dunkley AJ, Charles K, Gray LJ, Camosso-Stefinovic J, Davies MJ, Khunti K. Effectiveness of interventions for reducing diabetes and cardiovascular disease risk in people with metabolic syndrome: systematic review and mixed treatment comparison meta-analysis. Diabetes Obes Metab. 2012 Jul;14(7):616-625, doi:10.1111/j.1463-1326.2012.01571.x. PMID 22284386

Origin Investigators. n-3 Fatty Acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med. 2012 Jul 26;367(4):309-18 PMID 22686415

Dallosso H, Eborall H, Daly H, Martin-Lacey L, Speight J, Realf K, Carey ME, Campbell MJ, Dixon S, Khunti K, Davies MJ, Heller S. Does self-monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol. BMC Fam Pract. 2012 Mar 14;13:18, doi:10.1186/1471-2296-13-18. PMID 22416896

Khunti K, Davies MJ. Should we screen for type 2 diabetes: Yes. BMJ. 2012 Jul 9;345:e4515. PMID 22777029

The Origin Trial Investigators. Basal insulin and Cardiovascular and Other Outcomes in Dysglycemia. N Engl J Med. 2012 Jul 26;367(4):319-28. PMID 22686416

Willis A, Davies MJ, Yates T, Khunti K. Primary prevention of cardiovascular disease using validated risk scores: A Systematic Review. J R Soc Med. 2012 Aug;105(8):348-56, doi:10.1258/jrsm.2012.110193. PMID 22907552

Gray LJ, Cooper N, Dunkley A, Warren FC, Ara R, Davies MJ, Khunti K, Sutton A. A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity. Obes Rev. 2012 Jun;13(6):483-98, doi:10.1111/j.1467-789X.2011.00981.x. PMID 22288431

Kela R, Davies MJ. Treatment evaluation of liraglutide in type 2 diabetes. Expert Opin Biol Ther. 2012 Nov;12(11):1551-6, doi:10.1517/14712598.2012.716823. PMID 22897447

Ramachandran A, Riddle Carey ME, Kabali C, Gerstein HC, Origin Investigators. Relationship between A1c and fasting plasma glucose in dysglycemia or type 2 diabetes: an analysis of baseline data from the ORIGIN trial. Diabetes Care. 2012 Apr;35(4):749-53. PMID 22323416

Bharakhada N, Yates T, Davies MJ, Wilmot EG, Edwardson C, Henson J, Webb D, Khunti K. Association of sitting time and physical activity with CKD: A cross sectional study in family practices. Am J Kidney Dis. 2012 Oct;60(4):583-90. PMID 22717340

Hirsch IB, Bode B, Courreges JP, Dykiel P, Franek E, Hermansen K, King A, Mersebach H, Davies MJ. Insulin degludec/insulin aspart administered once daily at any meal, with insulin aspart at other meals versus a standard basal-bolus regimen in patients with type 1 diabetes: A 26 week, phase 3, randomized, open-label, treat-to-target trial. Diabetes Care. 2012 Nov;35(11):2174-2181, doi:10.2337/dc11-2503. PMID 22933438

Webb DR, Khunti K, Lacy P, Gray LJ, Mostafa S, Talbot D, Williams B, Davies MJ. Conduit vessel stiffness in British South Asians of Indian descent relates to 25-hydroxyvitam D status. J Hypertens. 2012 Aug;30(8):1588-96, doi:10.1097/HJH.0b013e328325f385. PMID 22688263

Armstrong N, Baines D, Baker R, Crossman R, Davies MJ, Hardy A, Khunti K, Humar S, O'Hare J, Raymond NT, Saravanan P, Stallard N, Szczepura A, Wilson A. A cluster randomised controlled trial of the effectiveness and cost-effectiveness of Intermediate Care Clinics for Diabetes (ICCD): Study protocol. Trials. 2012 Sep 12;13:164. PMID 22971356

Brady E, Webb D, Morris DH, Khunti K, Talbot DSC, Sattar N, Davies MJ. Investigating endothelial activation and oxidative stress in relation to glycaemic control in a multiethnic population. Exp Diabetes Res. 2012;2012:386041. doi: 10.1155/2012/386041. Epub 2012 Dec 6 PMID 23304116

Mostafa SA, Davies MJ, Morris DH, Yates T, Srinivasan BT, Webb D, Brady E, Khunti K. The association of the triglyceride-to-HDL cholesterol ratio with insulin resistance in White European and South Asian men and women. PLoS One. 2012;7(12):e50931. doi: 10.1371/journal.pone.0050931 PMID 23251403

Nisal K, Kela R, Khunti K, Davies MJ. Comparison of efficacy between incretin based therapies for type 2 diabetes mellitus. BMC Med. 2012 Nov 30;10(1):152, doi:10.1186/1741-7015-10-152. PMID 23198896

Mostafa S, Khunti K, Webb D, Srinivasan B, Grey L, Davies MJ. Independent effect of ethnicity on glycaemia in South Asians and White Europeans. Diabetes Care. 2012 Aug;35(8):1746-8, doi:10.2337/dc11-2079. PMID 22699291

Yates T, Davies MJ, Henson J, Troughton J, Edwardson C, Gray LJ, Khunti K. Walking away from type 2 diabetes: trial protocol of a cluster randomised controlled trial evaluating a structured education programme in those at high risk of developing type 2 diabetes. BMC Fam Pract. 2012 May 29;13:46, doi:10.1186/1471-2296-13-46. PMID 22642610

Pratley RE, Nauck MA, Bailey T, Montanya E, Filetti S, Garber AJ, Thomsen AB, Furber S, Davies MJ. Efficacy and Safety of Switching from the DPP-4 inhibitor Sitagliptin to the Human GLP-1 Analog Liraglutide After 52 Weeks in Metformin-treated Patients with Type 2 Diabetes: A Randomized, Open-label Trial. Diabetes Care. 2012 Oct;35(10):1986-93, doi:10.2337/dc11-2113. PMID 22851600

Wilmot EG, Edwardson CL, Achana FA, Davies MJ, Gorely T, Gray LJ, Khunti K, Yates T, Biddle SJ. Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia. 2012 Nov;55(11):2895-905 PMID 22890825

Simmons RK, Sharp SJ, Sandbaek A, Borch-Johnsen K, Davies MJ, Khunti K, Lauritzen T, Rutten GEHM, Van Den Donk M, Wareham NJ, Griffin S. Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomised trial. Diabet Med. 2012 Nov;29(11):e409-16, doi:10.1111/j.1464-5491-2012.03759.x. PMID 22823477

Gray LJ, Khunti K, Edwardson C, Goldby S, Henson J, Morris DH, Sheppard D, Webb D, Williams S, Yates T, Davies MJ. Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance. Diabetologia. 2012 Dec;55(12):3238-44, doi:10.1007/s00125-012-2725-8. PMID 23001376

Gholap N, Mehta RL, Ng L, Davies MJ, Khunti K, Squire IB. Is admission blood glucose concentration a more powerful predictor of mortality after myocardial infarction than diabetes diagnosis? A retrospective cohort study. BMJ Open. 2012 Sep 25;2(5), doi:10.1136/bmjopen-2012-001596. PMID 23015602

Davies MJ, Chubb BD, Smith IC. Cost-utility analysis of liraglutide compared with sulphonylurea or sitagliptin, all as add-on to Metformin monotherapy in Type 2 diabetes mellitus. Diabet Med. 2012 Mar;29(3):313-20, doi:10.1111/j.1464-5491.2011.03429.x. PMID 21883438

Webb D, Khunti K, Gray LJ, Srinivasan BT, Farooqi A, Wareham N, Griffin SC, Davies MJ. Intensive multifactorial intervention improves modelled coronary heart disease risk in screen detected Type 2 Diabetes Mellitus: a cluster randomised controlled trial. Diabet Med. 2012 Apr;29(4):531-40 PMID 21913966

Burton JO, Gray LJ, Davies MJ, Khunti K, Castro W, Carr SJ, Brunskill NJ. Association of anthropometric obesity measures with chronic kidney disease risk in a non-diabetic patient population. Nephrol Dial Transplant. 2012 May;27(5):1860-6 PMID 21965589

Nisal K, Gholap N, Davies MJ. Type 2 diabetes: tips and pitfalls in diagnosis and management. Prescriber 2012; 23(20):21-31

Griffin SJ, Davies MJ, Rutten GEHM, Lauritzen T. ADDITION-Europe and the case for diabetes screening. Author’s reply. The Lancet 379 (9813), 313 – 314, doi:10.1016/S0140-6736(12)60143-3.

Seidu S, Davies MJ, Roshan M, Daly H, Farooqi A, Khunti K. An evidence-based approach to quality` improvement in diabetes care. A review of the evidence on the quality improvement strategies relevant to the reconfiguration of diabetes services. Diabetes and Primary Care 2012; 14(6);334

Davies M, Khunti K, Webb D, Mostafa S, Gholap N, Crasto W, Gray L, Yates T, Brady E, Carter P, Sutton S, Bonar M, Fisher H. Updated. The Handbook for Vascular Risk Assessment, Risk Reduction and Risk Management; A report prepared for the UK National Screening Committee by the University of Leicester.

Chauhan A, Hiles S, Patel N, Stone MA, Davies MJ, Khunti K. Pharmacy based health checks – acceptable and feasible. Primary Care Cardiovascular Journal, 5, 74-76. 2012

Khunti K, Webb D, Srinivasan B, Stockman J, Griffin S, Simmons R, Davies MJ. Validity of self-assessed waist circumference in a multi-ethnic UK population. Diabet Med. 2012 Mar;29(3):404-9, doi:10.1111/j.1464-5491.2011.03478.x. PMID 21988535

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