Recombinant DNA and genetic techniques resources

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The recombinant DNA debate

An online tutorial about the recombinant DNA debate from Phillip McClean's Intermediate Genetics site.

Resource: North Dakota State University: recombinant DNA

Approach: Topic material

 

Problem set on recombinant DNA technology

A set of MCQs on recombinant DNA technology, including brief explanations and linked tutorials, from the Biology Project at the University of Arizona.

Resource: The Biology Project: recombinant DNA

Approach: Games and quizzes

 

Recombinant DNA technology (animation)

A 3-D animation on YouTube illustrating the process of gene cloning.

Resource: YouTube: recombinant DNA

Approach: Animation

 

GENIE Gene Cloning Tutorial

An activity that allows students to design a strategy to produce a medically important protein using recombinant DNA technology. Available as a card-based exercise for groups, or in a PowerPoint version for individuals.

Resource: GENIE gene cloning

Approach: Interactive tutorial

 

GENIE DNA Sequencing Tutorial

A GENIE tutorial allowing students to revise the process of DNA replication and the components required to perform the dideoxy (Sanger) method for DNA sequencing.

Resource: GENIE DNA sequencing

Approach: Interactive tutorial

 

Using a Micropipette (video)

An award-winning GENIE video introduction to the use of micropipettes in the laboratory for undergraduates and postgraduates. Total running time: 9 minutes.

Resource: GENIE Using a Micropipette

Watch the whole video

Part 1: Introduction

Part 2: Setting the Volume

Part 3: Pipette Tips

Part 4: Pipetting Volumes

Part 5: Common Things to Avoid

Approach: Video

 

Making and Running an Agarose Gel (video)

A GENIE video guide for postgraduate students illustrating the processes involved in making and running agarose gels in the laboratory. Total running time: 13 minutes.

Resource: GENIE Running an Agarose Gel

Watch the whole video

Part 1: Introduction

Part 2: Preparing the Gel

Part 3: Pouring the Gel

Part 4: Putting the Gel into the Gel Tank

Part 5: Loading the Samples

Part 6: Running the Gel

Part 7: Visualising the Nucleic Acids

Part 8: Common Things to Avoid

Approach: Video

 

Alec Jeffreys 'Eureka Moments'

As part of the biochemical society's centenary celebrations, a number of the Society’s Honorary Members were asked to talk about the important moments in their careers and the future of the discipline. The third to be released is that of Alec Jeffreys who spoke to John Armour about the 'Golden Age of Genetics'.

Resource: Golden Age of Genetics

Age range: 14-16/16-18

Approach: Video

 

Running an Agarose Gel (video)

A video guide for students illustrating the processes involved in running agarose gels in the laboratory. This is a shorter version of the GENIE video 'Making and Running an Agarose Gel'. Total running time: 6 minutes.

Resource: GENIE Running an Agarose Gel

Watch the whole video

Part 1: Introduction

Part 2: Loading the Samples

Part 3: Running the Gel

Part 4: Visualising the Nucleic Acids

Part 5: Common Things to Avoid

Approach: Video

 

Animated tutorials in molecular biology

Animated tutorials in molecular biology, including plasmid cloning, PCR and other genetic techniques, from Sumanas Inc. Can be viewed a step-through animations or as narrated, continuous animations.

Resource: Sumanas Inc: molecular biology 

Approach: Animation

 

Animated tutorial on gel electrophoresis

Animated tutorials on gel electrophoresis from Sumanas, Inc. Can be viewed as a step-through animation or as a narrated, continuous animation.

Resource: Sumanas Inc: gel electrophoresis

Approach: Animation

 

GENIE Restriction Enzyme Mapping of the lambda Phage Genome

This is a paper-based tutorial where students work out the complete map of the lambda phage genome from images of gel fragments.

Resource: GENIE Restriction Enzyme Mapping

Approach: Tutorial

 

How to set up a Southern Blot

This is a video produced by Robert Slater and shows the main steps involved in setting up a Southern Blot

Resource: Southern Blot

Approach: Video

 

The GENE Project

Teachers and research scientists adapting research organisms and laboratory techniques for use in the classroom to teach a wide variety of concepts and questions, Kansas State University, USA.

Resource: The GENE Project

Approach: Topic material

 

DNA Structure and Its Role in Forensic Science

A set of resources explaining how DNA is used in forensic science.

Resource: DNA Structure and Its Role in Forensic Science

Approach: Topic material

 

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