Sex, genomes, history: molecular, evolutionary and cultural effects on human genetic diversity (Wellcome Trust Senior Research Fellowship)

This project is building upon progress made in the previous two Fellowship terms by addressing two major questions:
• How has residence on the sex chromosomes affected the long- and short-term evolution of genic and non-genic sequences in primates? 
• How do the molecular evolutionary forces acting on these sequences interact with general and sex-specific population processes, and how can knowledge of molecular and population-level influences illuminate the histories of human populations themselves? 
 • To do this, we are exploiting the recent quantum leap in DNA sequencing and typing technology to provide a relatively unbiased and large-scale picture of diversity.

What’s in a name? Applying patrilineal surnames in forensics, population history and genetic epidemiology (Wellcome Trust Project Grant)

Family Tree

• In forensics: Given a suitable surname/Y-chromosome database, how confidently can we predict surname from Y-DNA profiles?
• In population genetics: Can we exploit historical surname lists to excavate past population structures (focus on Viking migrations)?
• In genetic epidemiology: Can we use the coancestry signalled by surname and haplotype sharing to improve the efficiency of searches for shared genome segments harbouring disease susceptibility alleles?

The Impact of Diasporas on the making of Britain

NRG YHG Distribution

This multidisciplinary collaboration draws on the world-class expertise of academics based in the University of Leicester in the Department of Genetics, the School of Archaeology and Ancient History, the School of Historical Studies and the School of English. We aim to reappraise key questions and evidence concerning the population history of Britain and the roots of the identities of the historical nations of the island, focusing especially on the methodological interfaces between academic disciplines. Funding comes from the Leverhulme Trust as a programme grant (PI: Prof Joanna Story, School of Historical Studies).

HALOGEN (History, Archaeology, Linguistics, Onomastics, GENetics): throwing light on the past through cross-disciplinary databasing (JISC project grant)

This project, run by colleagues in IT Services, aimed to build a cross-disciplinary database to support our other interdisciplinary projects.

Research Links

Search PubMed at the US National Library of Medicine for this author: Prof M. Jobling
Search Leicester Research Archive: Prof M. Jobling
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