Publications

Muñoz-Lopez M, Macia A, Garcia-Cañadas M, Badge RM, Garcia-Perez JL. An epi[c] genetic battle: LINE-1 retrotransposons and intragenomic conflict in humans. Mob Genet Elements. 2011 Jul;1(2):122-127. Epub 2011 Jul 1. PubMed PMID:22016860; PubMed Central PMCID: PMC3190314.

Macfarlane CM, Collier P, Rahbari R, Beck CR, Wagstaff JF, Igoe S, Moran JV, Badge RM
. Transduction-specific ATLAS reveals a cohort of highly active L1 retrotransposons in human populations. Hum Mutat. 2013 Jul;34(7):974-85. doi:10.1002/humu.22327. Epub 2013 Apr 23. PubMed PMID: 23553801; PubMed Central PMCID: PMC3880804.

Gray LJ, Leigh T, Davies MJ, Patel N, Stone M, Bonar M, Badge R, Khunti K. Systematic review of the development, implementation and availability of smart-phone applications for assessing type 2 diabetes risk. Diabet Med. 2013 Jun;30(6):758-60. doi: 10.1111/dme.12115. Review. PubMed PMID: 23683104.

Beck CR, Garcia-Perez JL, Badge RM, Moran JV. LINE-1 elements in structural variation and disease.  Annu Rev Genomics Hum Genet. 2011 Sep 22;12:187-215. Review. PMID: 21801021

Beck CR, Garcia-Perez JL, Badge RM, Moran JV. LINE-1 elements in structural variation and disease.  Annu Rev Genomics Hum Genet. 2011 Sep 22;12:187-215. Review. PMID: 21801021

Muñoz-Lopez M, Macia A, Garcia-Cañadas M, Badge RM, Garcia-Perez JL. An epi [c] genetic battle: LINE-1 retrotransposons and intragenomic conflict in humans.  Mob Genet Elements. 2011 Jul;1(2):122-127. Epub 2011 Jul 1. PMID: 22016860

Freeman P, Macfarlane C, Collier P, Jeffreys AJ, Badge RM. L1 hybridization enrichment: a method for directly accessing de novo L1 insertions in the human germline.  Hum Mutat. 2011 Aug;32(8):978-88. doi: 10.1002/humu.21533. Epub 2011 Jul 12. PMID: 21560187

Macia A, Muñoz-Lopez M, Cortes JL, Hastings RK, Morell S, Lucena-Aguilar G, Marchal JA, Badge RM, Garcia-Perez JL. Epigenetic control of retrotransposon expression in human embryonic stem cells.
Mol Cell Biol. 2010 Nov 1. [Epub ahead of print] PMID: 21041477

Ray A, Rahbari R, Badge RM. IAP Display: A Simple Method to Identify Mouse Strain Specific IAP Insertions.
Mol Biotechnol. 2010 Sep 26. [Epub ahead of print] PMID: 20872285

Beck CR, Collier P, Macfarlane C, Malig M, Kidd JM, Eichler EE, Badge RM, Moran JV.
LINE-1 retrotransposition activity in human genomes. Cell. 2010 Jun 25;141(7):1159-70. PubMed PMID: 20602998.

Rahbari R, Sheahan T, Modes V, Collier P, Macfarlane C, Badge RM. A novel L1 retrotransposon marker for HeLa cell line identification. Biotechniques. 2009 Apr;46(4):277-84. PubMed PMID: 19450234; PubMed Central PMCID: PMC2696096.

Zemojtel T, Penzkofer T, Schultz J, Dandekar T, Badge R, Vingron M.
Exonization of active mouse L1s: a driver of transcriptome evolution? BMC
Genomics. 2007 Oct 26;8:392. PubMed PMID: 17963496; PubMed Central PMCID: PMC2176070.

Athanikar JN, Badge RM, Moran JV. A YY1-binding site is required for accurate  human LINE-1 transcription initiation. Nucleic Acids Res. 2004 Jul 22;32(13):3846-55. Print 2004. PubMed PMID: 15272086; PubMed Central PMCID:PMC506791.

Brouha B, Schustak J, Badge RM, Lutz-Prigge S, Farley AH, Moran JV, Kazazian HH Jr. Hot L1s account for the bulk of retrotransposition in the human population. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5280-5. Epub 2003 Apr 7. PubMed PMID: 12682288; PubMed Central PMCID: PMC154336.

Badge RM, Alisch RS, Moran JV. ATLAS: a system to selectively identify
human-specific L1 insertions. Am J Hum Genet. 2003 Apr;72(4):823-38. Epub 2003 Mar 11. PubMed PMID: 12632328; PubMed Central PMCID: PMC1180347.

Cheng YC, Lee CJ, Badge RM, Orme AT, Scotting PJ. Sox8 gene expression
identifies immature glial cells in developing cerebellum and cerebellar tumours. Brain Res Mol Brain Res. 2001 Aug 15;92(1-2):193-200. PubMed PMID: 11483257.

Badge RM, Yardley J, Jeffreys AJ, Armour JA. Crossover breakpoint mapping
identifies a subtelomeric hotspot for male meiotic recombination. Hum Mol Genet. 2000 May 1;9(8):1239-44. PubMed PMID: 10767349.

Badge RM, Brookfield JF. A novel repressor of P element transposition in
Drosophila melanogaster. Genet Res. 1998 Feb;71(1):21-30. PubMed PMID: 9674380.

Badge RM, Brookfield JF. The role of host factors in the population dynamics
of selfish transposable elements. J Theor Biol. 1997 Jul 21;187(2):261-71. PubMed PMID: 9237896.

Brookfield JF, Badge RM. Population genetics models of transposable elements. Genetica. 1997;100(1-3):281-94. PubMed PMID: 9440281.

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Contact Details

Department of Genetics
University of Leicester

Adrian Building
University Road
Leicester
LE1 7RH
United Kingdom

Tel: +44 (0)116 252 3374
Fax: +44 (0)116 252 3378
E Mail: genetics@le.ac.uk

Head of Department
Professor Alison Goodall

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